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Source: Journal of Cellular Biochemistry
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Total 134 results found since Jan 2013.
Long noncoding RNA GAS5 suppresses cell growth and epithelial ‐mesenchymal transition in osteosarcoma by regulating the miR‐221/ARHI pathway
This study explored the potential functions and mechanisms of GAS5 in the tumorigenesis of osteosarcoma. Here, the expression of GAS5, miR‐221 and aplasia Ras homologue member I (ARHI) was determined in osteosarcoma tissues and cells by Real‐time PCR (RT‐qPCR). The underlying mechanism of GAS5 in osteosarcoma growth was analyzed via MTT, Transwell, RT‐qPCR, Western blot, dual‐luciferase reporter assay, RNA immunoprecipitation, and xenograft models after GAS5 overexpression. GAS5 and ARHI levels were significantly reduced, while miR‐221 increased, both in osteosarcoma tissues and cells. Overexpression of GAS5 su...
Source: Journal of Cellular Biochemistry - May 18, 2017 Category: Biochemistry Authors: Kaishan Ye, Shuanke Wang, Haihong Zhang, Hua Han, Bing Ma, Wei Nan Tags: Article Source Type: research
Activation of the Nrf2 ‐ARE Signaling Pathway Prevents Hyperphosphatemia‐Induced Vascular Calcification by Inducing Autophagy in Renal Vascular Smooth Muscle Cells
This study investigates the effect of nuclear factor erythroid 2‐related factor 2‐antioxidant response element (Nrf2‐ARE) signaling pathway in vascular calcification (VC) via inducing Autophagy in renal vascular smooth muscle cells (VSMCs). VSMCs were assigned into six experimental groups: the normal control, high phosphorus, si‐negative control (si‐NC), Nrf2‐siRNA, over‐expressed Nrf2 and negative control (NC) groups. RT‐PCR was applied to detect the mRNA expressions of the desired Nrf2‐ARE signaling pathway‐related genes (Nrf2, NQO‐1, HO‐1, γ‐GCS). The protein products of these genes: apoptosis...
Source: Journal of Cellular Biochemistry - May 17, 2017 Category: Biochemistry Authors: Li Yao, Jian Wang, Bin ‐Yao Tian, Tian‐Hua Xu, Zi‐Tong Sheng Tags: Resaearch Article Source Type: research
Licochalcone A Suppresses Specificity Protein 1 as a Novel Target in Human Breast Cancer Cells
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Source: Journal of Cellular Biochemistry - May 12, 2017 Category: Biochemistry Authors: Tae ‐Ho Kang, Ji‐Hye Seo, Hana Oh, Goo Yoon, Jung‐Il Chae, Jung‐Hyun Shim Tags: Article Source Type: research
SNX10 plays a critical role in MMP9 secretion via JNK ‐p38‐ERK signaling pathway
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Source: Journal of Cellular Biochemistry - May 12, 2017 Category: Biochemistry Authors: Chun Zhou, Ying Wang, Jin Peng, Cuixian Li, Peiqing Liu, Xiaoyan Shen Tags: Article Source Type: research
Role of Small Interfering RNA Silencing Protein Kinase C ‐α Gene on the Occurrence of Ultrafiltration Failure in Peritoneal Dialysis Rats
This study aims to explore the effect of PKC‐α gene silencing on the occurrence of ultrafiltration failure (UFF) in peritoneal dialysis (PD) rats. Forty‐eight male SD rats were collected to establish 5/6 renal resection uremic and uremic PD rats models. Rats were assigned into control, sham operation, uremia, PD‐2 W (peritoneal dialysis for 2 weeks), PD‐4 W (peritoneal dialysis for 4 weeks), negative control (NC) (peritoneal dialysis for 4 weeks, and injected 0.1 mg/kg blank plasmid into abdominal cavity) and PKC‐α siRNA (peritoneal dialysis for 4 weeks, and injected 0.1 mg/kg PKC‐α siRNA into abdomi...
Source: Journal of Cellular Biochemistry - May 9, 2017 Category: Biochemistry Authors: Zhi ‐Wei Sun, Jian Wang, Min Weng, Jian‐Zhong Tang, Jun‐Feng Wang, Jian Xu, Ling Lin, Hong‐Ling Yuan Tags: Article Source Type: research
Activition Of TLR7 Inhibition Of Mycobacterium Tuberculosis Survival By Autophagy In RAW 264.7 Macrophages
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Source: Journal of Cellular Biochemistry - April 17, 2017 Category: Biochemistry Authors: Meng Bao, Zhengjun Yi, Yurong Fu Tags: Article Source Type: research
Runt ‐related transcription factor 2 (Runx2) is responsible for galectin‐3 overexpression in human thyroid carcinoma
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Source: Journal of Cellular Biochemistry - April 11, 2017 Category: Biochemistry Authors: Engin Kaptan, Serap Sancar Bas, Aylin Sancakli, Hatice Gumushan Aktas, Bertan Boran Bayrak, Refiye Yanardag, Sehnaz Bolkent Tags: Article Source Type: research
Oncophosphosignaling Favors a Glycolytic Phenotype in Human Drug Resistant Leukemia
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Source: Journal of Cellular Biochemistry - April 7, 2017 Category: Biochemistry Authors: Alessandra V. S. Faria, Tha ís F. Tornatore, Renato Milani, Karla C. S. Queiroz, Igor H. Sampaio, Emanuella M. B. Fonseca, Karin J. P. Rocha‐Brito, Tamira Oliveira Santos, Leonardo R. Silveira, Maikel P. Peppelenbosch, Carmen Veríssima Ferreira‐Hald Tags: Article Source Type: research
Wnt/ β‐catenin Signaling Activates Expression of the Bone‐related Transcription Factor RUNX2 in Select Human Osteosarcoma Cell Types
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Source: Journal of Cellular Biochemistry - March 28, 2017 Category: Biochemistry Authors: Oscar A. Vega, Claudia M.J. Lucero, Hector F. Araya, Sofia Jerez, Julio C. Tapia, Marcelo Antonelli, Flavio Salazar ‐Onfray, Facundo Las Heras, Roman Thaler, Scott M. Riester, Gary S. Stein, Andre J. van Wijnen, Mario A. Galindo Tags: Article Source Type: research
Angiopoietin ‐2 Enhances Osteogenic Differentiation of Bone Marrow Stem Cells
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Source: Journal of Cellular Biochemistry - February 17, 2017 Category: Biochemistry Authors: Mi ‐Lan Kang, Eun‐Ah Kim, Se‐Young Jeong, Gun‐Il Im Tags: Article Source Type: research
Human Th17 Migration in Three ‐dimensional Collagen Involves p38 MAPK
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Source: Journal of Cellular Biochemistry - February 15, 2017 Category: Biochemistry Authors: Maleck Kadiri, Mohamed ‐Amine El Azreq, Sofiane Berrazouane, Marc Boisvert, Fawzi Aoudjit Tags: Article Source Type: research
Calcium Uptake via Mitochondrial Uniporter Contributes to Palmitic Acid ‐induced Apoptosis in Mouse Podocytes
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Source: Journal of Cellular Biochemistry - February 9, 2017 Category: Biochemistry Authors: Zeting Yuan, Aili Cao, Hua Liu, Henjiang Guo, Yingjun Zang, Yi Wang, Yunman Wang, Hao Wang, Peihao Yin, Wen Peng Tags: Article Source Type: research
Upregulation of SRF Is Associated with Hypoxic Pulmonary Hypertension by Promoting Viability of Smooth Muscle Cells via Increasing Expression of Bcl ‐2
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Source: Journal of Cellular Biochemistry - February 7, 2017 Category: Biochemistry Authors: Xing Ding, Sijing Zhou, Min Li, Chao Cao, Peipei Wu, Li Sun, Guanghe Fei, Ran Wang Tags: Article Source Type: research
Enhanced Aerobic Glycolysis by S ‐nitrosoglutathione via HIF‐1α Associated GLUT1/Aldolase A Axis in Human Endothelial Cells
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Source: Journal of Cellular Biochemistry - January 24, 2017 Category: Biochemistry Authors: Jieping Yan, Xin Huang, Danyan Zhu, Yijia Lou Tags: Article Source Type: research
Inhibition of Inositol 1, 4, 5 ‐trisphosphate Receptor Induce Breast Cancer Cell Death through Deregulated Autophagy and Cellular Bioenergetics
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Source: Journal of Cellular Biochemistry - January 19, 2017 Category: Biochemistry Authors: Aru Singh, Megha Chagtoo, Swasti Tiwari, Nelson George, Bandana Chakravarti, Sajid Khan, Sripada Lakshmi, Madan M Godbole Tags: Article Source Type: research
