Filtered By:
Cancer: Prostate Cancer
Drug: Docetaxel
This page shows you your search results in order of date.
Order by Relevance | Date
Total 100 results found since Jan 2013.
Androgen receptor knockdown enhances prostate cancer chemosensitivity by down ‐regulating FEN1 through the ERK/ELK1 signalling pathway
ConclusionCollectively, our studies demonstrate that AR knockdown improves the DTX sensitivity of prostate cancer cells by downregulating FEN1 through the ERK/ELK1 signalling pathway.
Source: Cancer Medicine - June 16, 2023 Category: Cancer & Oncology Authors: Weijie Xie,
Shulin Li,
Huan Guo,
Jiawei Zhang,
Menjiang Tu,
Rui Wang,
Bingling Lin,
Yuqi Wu,
Xiangwei Wang Tags: RESEARCH ARTICLE Source Type: research
The CCL2-CCR2 Axis Contributes to Migration of Cabazitaxel-resistant Prostate Cancer Cells
CONCLUSION: The CCL2-CCR2 axis is a key contributor to resistance to the antimigration effect of cabazitaxel in prostate cancer cells. CCL2-CCR2 axis inhibition may be a potential therapeutic target against chemoresistant CRPC in combination with cabazitaxel.PMID:37247914 | DOI:10.21873/anticanres.16423
Source: Cell Research - May 29, 2023 Category: Cytology Authors: Ariunbold Natsagdorj Kouji Izumi Kaoru Hiratsuka Renato Naito Suguru Kadomoto Hiroaki Iwamoto Hiroshi Yaegashi Kazuyoshi Shigehara Hiroki Nakata Atsushi Mizokami Source Type: research
Knockdown of USP8 inhibits prostate cancer cell growth, proliferation, and metastasis and promotes docetaxel ’s activity by suppressing the NF-kB signaling pathway
Ubiquitin-specific protease 8 (USP8) has been recently reported to be involved in tumorigenesis. Prostate cancer (PCa) is the most diagnosed malignancy among men, but USP8’s role in PCa is not yet investigated comprehensively. Therefore, the PCa cell lines DU145 and PC3 were transfected with USP8 siRNA or overexpressing vector together with or without docetaxel. The silencing USP8 and docetaxel treatment reduced cell viability and migration and promoted apoptosis. In contrast, USP8 knockdown was found to enhance docetaxel antitumor activity. In contrast, increased cell viability and migration were noticed upon USP8 overe...
Source: Frontiers in Oncology - October 20, 2022 Category: Cancer & Oncology Source Type: research
Decreased Expression of HN1 Sensitizes Prostate Cancer Cells to Apoptosis Induced by Docetaxel and 2-Methoxyestradiol
CONCLUSION: HN1 is an anti-apoptotic molecule and inhibits Docetaxel and 2-Methoxyestradiol induced apoptosis by targeting Cyclin B1.PMID:35414498
Source: Annals of Clinical and Laboratory Science - April 13, 2022 Category: Laboratory Medicine Authors: Lokman Varisli Source Type: research
