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Condition: Reflex Sympathetic Dystrophy
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Total 132 results found since Jan 2013.
K < sub > V < /sub > 4 channels in isolectin B4 muscle dorsal root ganglion neurons of rats with experimental peripheral artery disease: Effects of bradykinin B1 and B2 receptors
In conclusion, our data suggest that limb ischemia and/or ischemia induced-BK inhibit activity of KV4 channels in a subpopulation of the thin fiber muscle afferent neurons depending on GDNF, which is likely a part of signaling pathways involved in the exaggerated blood pressure response during activation of muscle afferent nerves in PAD.PMID:36094447 | DOI:10.1152/ajpregu.00117.2022
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - September 12, 2022 Category: Physiology Authors: Qin Li Lu Qin Jianhua Li Source Type: research
NanoSPECT imaging reveals the uptake of 123I-labeled oxidized low-density lipoprotein in the brown adipose tissue of mice via CD36
CONCLUSION: We show novel evidence for the CD36-mediated accumulation of oxLDL in BAT, suggesting that BAT may exert its anti-atherogenic effects by removing atherogenic LDL from the circulation.PMID:36266737 | DOI:10.1093/cvr/cvac167
Source: Cell Research - October 21, 2022 Category: Cytology Authors: Kento Hosomi Hidekazu Kawashima Atsushi Nakano Akemi Kakino Yuko Okamatsu-Ogura Yuki Yamashita Mai Sasaoka Daisaku Masuda Shizuya Yamashita Chu-Huang Chen Shunsuke Yuzuriha Hiroshi Hosoda Hidehiro Iida Tatsuya Sawamura Source Type: research
Gamma secretase activity modulates BMP-7-induced dendritic growth in primary rat sympathetic neurons
In this study, we examined whether the γ-secretase pathway also influences dendritic growth in primary sympathetic neurons. Using immunoblotting and immunocytochemistry, molecules of the γ-secretase complex, PSEN1, PSEN2, PEN2, nicastrin and APH1a, were detected in sympathetic neurons dissociated from embryonic (E20/21) rat sympathetic ganglia. Addition of bone morphogenetic protein-7 (BMP-7), which induces dendrites in these neurons, did not alter expression or localization of γ-secretase complex proteins. BMP-7-induced dendritic growth was inhibited by siRNA knockdown of PSEN1 and by three γ-secretase inhibitors, γ-...
Source: Autonomic Neuroscience - April 9, 2023 Category: Neuroscience Authors: Krystal Karunungan Rachel H Garza Ana Cristina Grodzki Megan Holt Pamela J Lein Vidya Chandrasekaran Source Type: research
