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Cancer: Endometrial Cancer
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Total 190 results found since Jan 2013.
Targeting CDK9: A novel biomarker in the treatment of endometrial cancer.
In conclusion, our results provide evidence that CDK9 may be a potential prognostic biomarker and a promising therapeutic target for the treatment of endometrial cancer in the future.
PMID: 32901849 [PubMed - as supplied by publisher]
Source: Oncology Reports - September 10, 2020 Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
PGC-1 α and ERRα in patients with endometrial cancer: a translational study for predicting myometrial invasion.
CONCLUSIONS: PGC-1α and ERRα induce the epithelial-mesenchymal-transition therefore invasion and migration in endometrial cancer, and may be novel biomarkers to predict the risk of advanced myometrial invasion.
METHODS: PGC-1α, ERRα, and vimentin expression was analyzed in tissue microarrays using immunohistochemistry. PGC-1α and ERRα expression in endometrial cancer cell lines was investigated using quantitative PCR and western blotting analyses after infection with lentivirus-mediated small interfering RNA (siRNA) targeting PGC-1α (siRNA-PGC-1α) or overexpressing ERRα. E-cadherin and vimentin levels were de...
Source: Aging - September 12, 2020 Category: Biomedical Science Authors: Chen L, Mao X, Huang M, Lei H, Xue L, Sun P Tags: Aging (Albany NY) Source Type: research
Role of miR-139-5p in ectopic endometrial stromal cells and the underlying molecular mechanism
In conclusion, the results of the present study suggested that miR-139-5p may play a key role in the progression of endometriosis by regulating the viability of ESCs and directly targeting BBC3.PMID:34539847 | PMC:PMC8438670 | DOI:10.3892/etm.2021.10686
Source: Experimental and Therapeutic Medicine - September 20, 2021 Category: General Medicine Authors: Lixia Feng Xu Chen Shenghua Zhang Yunxia Chen Yanling Yu Source Type: research
Apolipoprotein E enhances migration of endometrial cancer cells byactivating the ERK/MMP9 signaling pathway
CONCLUSION: APOE is highly expressed in endometrial cancer tissues to promote cancer cell migration by enhancing ERK phosphorylation and MMP9 expression.PMID:36946043 | DOI:10.12122/j.issn.1673-4254.2023.02.11
Source: Cancer Control - March 22, 2023 Category: Cancer & Oncology Authors: C Wu W Cheng Source Type: research
