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Cancer: Glioma

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Total 625 results found since Jan 2013.

MiR-489 inhibits proliferation and apoptosis of glioblastoma multiforme cells via regulating TWIST1 expression.
CONCLUSIONS: MiR-489 can repress the proliferation and promote the apoptosis of glioma cells by targeting TWIST1. PMID: 33455101 [PubMed - in process]
Source: Journal of B.U.ON. - January 20, 2021 Category: Cancer & Oncology Tags: J BUON Source Type: research

RNA Interference-Mediated Aurora Kinase A Gene Silencing Inhibits Human Glioma Cells Proliferation and Tumor Growth in Mice
Conclusion: Aurora A can be used as a candidate targeting gene and inhibition of Aurora A is a potentially promising therapy for glioblastoma.
Source: Journal of Cancer - April 19, 2021 Category: Cancer & Oncology Authors: Ge Zhang, Guanghui Ren, Xin Zhao, Haibo Wang Tags: Research Paper Source Type: research

Insulin receptor substrate 1 gene expression is strongly up-regulated by HSPB8 silencing in U87 glioma cells
Conclusions. Results of this investigation demonstrated that silencing of HSPB8 mRNA affected the expression of IRS1 gene as well as many other genes encoding tumor growth related proteins. It is possible that the dysregulation of most of the studied genes in glioma cells after silencing of HSPB8 is reflected by a complex of intergenic interactions and that this polyfunctional chaperone is an important factor for the stability of genome function and regulatory mechanisms contributing to the tumorigenesis control.PMID:33885248 | DOI:10.2478/enr-2020-0026
Source: Endocrine Regulations - April 22, 2021 Category: Endocrinology Authors: Oksana S Hnatiuk Dariia O Tsymbal Dmytro O Minchenko Olena O Khita Yulia M Viletska Olha V Rundytska Halyna E Kozynkevych Hanna S Maslak Oleksandr H Minchenko Source Type: research