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Total 2131 results found since Jan 2013.

ZNF746 promotes M2 macrophage polarisation and favours tumour progression in breast cancer via the Jagged1/Notch pathway
In conclusion, this study uncovers the role of ZNF746 in promoting M2 macrophage polarisation and suggests that ZNF746 may be a promising therapeutic target for limiting BC progression.PMID:37730102 | DOI:10.1016/j.cellsig.2023.110892
Source: Cellular Signalling - September 20, 2023 Category: Cytology Authors: Lu Liu Wen-Yue Zhao Xin-Yu Zheng Source Type: research

Acetyl-cinobufagin suppresses triple-negative breast cancer progression by inhibiting the STAT3 pathway
CONCLUSIONS: The findings of this study support the potential clinical use of acetyl-cinobufagin as a STAT3 inhibitor in TNBC adjuvant therapy.PMID:37651362 | DOI:10.18632/aging.204967
Source: Aging - August 31, 2023 Category: Biomedical Science Authors: Yufeng Qi Haodong Wu Tianru Zhu Zitian Liu Conghui Liu Congzhi Yan Zhixuan Wu Yiying Xu Ying Bai Lehe Yang Dezhi Cheng Xiaohua Zhang Haiyang Zhao Chengguang Zhao Xuanxuan Dai Source Type: research

Exosomes are involved in the intercellular transfer of rapamycin resistance in the breast cancer cells
CONCLUSION: We propose that DNA demethylation followed by increased expression of key genes may be one of the factors responsible for the progression and maintenance of the resistant cell phenotype that includes exosome-induced resistance.PMID:37645026 | PMC:PMC10460766 | DOI:10.34172/bi.2023.27490
Source: BioImpacts - August 30, 2023 Category: Research Authors: Yuri Yu Shchegolev Danila V Sorokin Alexander M Scherbakov Olga E Andreeva Diana I Salnikova Ekaterina I Mikhaevich Margarita V Gudkova Mikhail A Krasil'nikov Source Type: research