Filtered By:
Specialty: Cardiology
This page shows you your search results in order of date. This is page number 12.
Order by Relevance | Date
Total 109613 results found since Jan 2013.
From the inside out: understanding the gut-heart connection
Future Cardiol. 2023 Sep 18. doi: 10.2217/fca-2023-0068. Online ahead of print.ABSTRACTThe gut microbiome was first termed as 'Animalcules' by Antonie van Leeuwenhoek in the 17th century. The diverse composition and complex interactions of gut microbes are essential for good human health. They play a crucial role in inflammation, which by itself leads to the development of cardiovascular diseases. Although the mechanisms are not fully understood, it has been studied that the gut microbiota produce several bioactive metabolites impacting cardiovascular health mainly through TMAO pathway, SCFA pathway and bile acid pathway. ...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Akanksha Mahajan Deepthi Bandaru Kinna Parikh Vasu Gupta Meet Patel Source Type: research
Atherosclerosis as a Risk Factor for IBD: A Population-Based Case-Control Study
CONCLUSIONS: A history of an atherosclerotic-related condition is associated with increased odds of developing IBD, particularly among older adults. Future studies should investigate whether drugs targeting atherosclerotic-related inflammation may prevent IBD in higher-risk individuals.PMID:37721310 | DOI:10.14309/ajg.0000000000002502
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Adam S Faye Jordan Axelrad Jiangwei Sun Jonas Halfvarson Jonas S öderling Ola Ol én Jonas F Ludvigsson Source Type: research
Integrating Chemical Profiling, In Vivo Study, and Network Pharmacology to Explore the Anti-inflammatory Effect of < em > Pterocarpus dalbergioides < /em > Fruits and Its Correlation with the Major Phytoconstituents
ACS Omega. 2023 Aug 29;8(36):32544-32554. doi: 10.1021/acsomega.3c02940. eCollection 2023 Sep 12.ABSTRACTThe purpose of this study is to explore the anti-inflammatory activity of Pterocarpus dalbergioides fruit extract (PFE) and the underlying mechanism. Chemical profiling using ultraperformance liquid chromatography/mass spectrometry identified 28 compounds in PFE (12 flavonoids, 5 fatty acids, 4 phenolic compounds, 3 alkaloids, 2 sesquiterpenes, and 2 xanthophylls). PFE (2 g/kg) significantly inhibited carrageenan-induced rat paw edema after 4 h of administration (42% inhibition). A network-based strategy and molecular d...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Taghreed S Alnusaire Ibrahim Lahbib Sabouni Hanan Khojah Sumera Qasim Mohammad M Al-Sanea Sadaf Siddique Fatma Alzahraa Mokhtar Shaimaa R Ahmed Source Type: research
Effectiveness of Device-Guided Breathing in Chronic Coronary Syndrome: A Randomized Controlled Study
CONCLUSIONS: An 8-week long program of short-term respiratory muscle training provided positive gains in exercise capacity and angina severity in CCS patients with angina. The effects of long-term training programs on CCS patients should be investigated clinically because of the possibility of helping to decrease the need for invasive treatments.PMID:37720408 | PMC:PMC10499964 | DOI:10.6515/ACS.202309_39(5).20230306E
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Oguz Akkus Irem Huzmeli Taner Seker Ozkan Bekler Fatih Sen Onur Kaypakli Aysel Yildiz Ozer Fatih Yalcin Source Type: research
Erratum: "Microfluidic-to-macrofluidic: A simple < em > in vitro < /em > model of atherosclerosis induced by fluidic stimulation" Biomicrofluidics 17, 044106 (2023)
Biomicrofluidics. 2023 Sep 13;17(5):059901. doi: 10.1063/5.0174489. eCollection 2023 Sep.ABSTRACT[This corrects the article DOI: 10.1063/5.0155267.].PMID:37720303 | PMC:PMC10501804 | DOI:10.1063/5.0174489
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Jingang Cui Wei Jiang Jilei Su Jiazhen Zhang Yongliang Yu Yongsheng Ding Source Type: research
Lipoprotein(a), Interleukin-6 inhibitors, and atherosclerotic cardiovascular disease: Is there an association?
CONCLUSIONS: Although the effect of IL-6(R)i on Lp(a) levels is inferior to that of available Lp(a)-lowering therapies, the dual effect of the former on both inflammation and apolipoprotein (a) synthesis may prove of equal or even greater significance when it comes ASCVD outcomes. More trials are required to establish IL-6(R)i in ASCVD prevention and elucidate their interplay with Lp(a) as well as its clinical significance.PMID:37720252 | PMC:PMC10500445 | DOI:10.1016/j.athplu.2023.09.001
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Anastasios Makris Fotios Barkas Petros P Sfikakis Evangelos Liberopoulos Theodosios D Filippatos Kausik K Ray Aris P Agouridis Source Type: research
3,3-dimethyl-1-butanol and its metabolite 3,3-dimethylbutyrate ameliorate collagen-induced arthritis independent of choline trimethylamine lyase activity
Res Sq. 2023 Sep 5:rs.3.rs-3297018. doi: 10.21203/rs.3.rs-3297018/v1. Preprint.ABSTRACTPrevious studies have identified significant alterations in intestinal carnitine metabolism in mice with collagen-induced arthritis (CIA), potentially linking bacterial dysbiosis with autoimmunity. Bacterial trimethylamine (TMA) lyases metabolize dietary carnitine to TMA, which is oxidized in the liver to trimethylamine-N-oxide (TMAO). TMAO is associated with inflammatory diseases, such as atherosclerosis, whose immunologic processes mirror that of rheumatoid arthritis (RA). Therefore, we investigated the possibility of ameliorating CIA ...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Sabrina Fechtner Brendan E Allen Meagan E Chriswell Widian K Jubair Charles E Robertson Jennifer N Kofonow Daniel N Frank V Michael Holers Kristine A Kuhn Source Type: research
Non-coding RNAs are key players and promising therapeutic targets in atherosclerosis
Front Cell Dev Biol. 2023 Sep 1;11:1237941. doi: 10.3389/fcell.2023.1237941. eCollection 2023.ABSTRACTCardiovascular disease (CVD) is the primary cause of death in humans. Atherosclerosis (AS) is the most common CVD and a major cause of many CVD-related fatalities. AS has numerous risk factors and complex pathogenesis, and while it has long been a research focus, most mechanisms underlying its progression remain unknown. Noncoding RNAs (ncRNAs) represent an important focus in epigenetics studies and are critical biological regulators that form a complex network of gene regulation. Abnormal ncRNA expression disrupts the nor...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Zhun Yu JinZhu Yin ZhiTong Tang Ting Hu ZhuoEr Wang Ying Chen Tianjia Liu Wei Zhang Source Type: research
Targeting gut microbiota and immune crosstalk: potential mechanisms of natural products in the treatment of atherosclerosis
Front Pharmacol. 2023 Sep 1;14:1252907. doi: 10.3389/fphar.2023.1252907. eCollection 2023.ABSTRACTAtherosclerosis (AS) is a chronic inflammatory reaction that primarily affects large and medium-sized arteries. It is a major cause of cardiovascular disease and peripheral arterial occlusive disease. The pathogenesis of AS involves specific structural and functional alterations in various populations of vascular cells at different stages of the disease. The immune response is involved throughout the entire developmental stage of AS, and targeting immune cells presents a promising avenue for its treatment. Over the past 2 deca...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Jinpeng Jing Jing Guo Rui Dai Chaojun Zhu Zhaohui Zhang Source Type: research
Comparison of seven surrogate insulin resistance indexes for predicting the prevalence of carotid atherosclerosis in normal-weight individuals
CONCLUSION: CVAI, TyG-WC, TyG-WHtR and LAP were independently associated with the prevalence of CA. Specifically, CVAI may be the most appropriate predictor of CA in normal-weight individuals.PMID:37719743 | PMC:PMC10501451 | DOI:10.3389/fpubh.2023.1241523
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Zeyu Liu Bi Deng Qin Huang Ruxin Tu Fang Yu Jian Xia Jie Feng Source Type: research
Understanding the Link Between Adult Asthma and Coronary Artery Disease: A Narrative Review
Cureus. 2023 Aug 17;15(8):e43621. doi: 10.7759/cureus.43621. eCollection 2023 Aug.ABSTRACTAsthma is a common pathology worldwide that occurs due to chronic inflammation of the respiratory airways. Persistent pulmonary inflammation leads to low-grade systemic inflammation, influencing blood vessels and triggering coronary artery disease (CAD) events. This review's objectives include discussing the susceptible population for CAD, the mechanism underlying CAD creation in asthma patients, the characteristics of asthma, and the influence of anti-asthmatic medications on CAD development. Adult-onset asthma is strongly linked to ...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Vasudha S Garg Mihir H Sojitra Tyagi J Ubhadiya Nidhi Dubey Karan Shah Siddharth Kamal Gandhi Priyansh Patel Source Type: research
A 96-wells fluidic system for high-throughput screenings under laminar high wall shear stress conditions
Microsyst Nanoeng. 2023 Sep 15;9:114. doi: 10.1038/s41378-023-00589-x. eCollection 2023.ABSTRACTThe ability of endothelial cells to respond to blood flow is fundamental for the correct formation and maintenance of a functional and hierarchically organized vascular network. Defective flow responses, in particular related to high flow conditions, have been associated with atherosclerosis, stroke, arteriovenous malformations, and neurodegenerative diseases. Yet, the molecular mechanisms involved in high flow response are still poorly understood. Here, we described the development and validation of a 96-wells fluidic system, w...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Catarina Gon çalves Fonseca V ânia Silvério David Barata Wolfgang Giese Holger Gerhardt Susana Cardoso Claudio Areias Franco Source Type: research
LPS adsorption and inflammation alleviation by polymyxin B-modified liposomes for atherosclerosis treatment
Acta Pharm Sin B. 2023 Sep;13(9):3817-3833. doi: 10.1016/j.apsb.2023.06.005. Epub 2023 Jun 13.ABSTRACTChronic inflammation is critical in the onset and progression of atherosclerosis (AS). The lipopolysaccharide (LPS) level in the circulation system is elevated in AS patients and animal models, which is correlated with the severity of AS. Inspired by the underlying mechanism that LPS could drive the polarization of macrophages toward the M1 phenotype, aggravate inflammation, and ultimately contribute to the exacerbation of AS, LPS in the circulation system was supposed to be the therapeutic target for AS treatment. In the ...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Huiwen Liu Honglan Wang Qiyu Li Yiwei Wang Ying He Xuejing Li Chunyan Sun Onder Ergonul F üsun Can Zhiqing Pang Bo Zhang Yu Hu Source Type: research
The mechanism of Plantaginis Semen in the treatment of diabetic nephropathy based on network pharmacology and molecular docking technology
CONCLUSION: PS can have the treatment on DN through CASP3. Quercetin, as one of the nine active ingredients, can be bounded to CASP3 to inhibit apoptosis in DN. PS can also take action on DN probably through many pathways. The role of PS on DN through other pathways still needs to be further elaborated.PMID:37718520 | DOI:10.2174/1871530323666230915100355
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Linlin He Kai Shen Lei He Yuqing Chen Zhiyuan Tang Source Type: research
The Role of Ablation-Based Rhythm Control in the Tangled Web of Atrial Fibrillation and Heart Failure
Circulation. 2023 Sep 19;148(12):933-935. doi: 10.1161/CIRCULATIONAHA.123.065329. Epub 2023 Sep 18.NO ABSTRACTPMID:37721977 | DOI:10.1161/CIRCULATIONAHA.123.065329
Source: Circulation - September 18, 2023 Category: Cardiology Authors: Ratika Parkash Eileen O'Meara Anthony S L Tang Source Type: research
