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Total 182491 results found since Jan 2013.

Cryotherapy following total knee replacement
CONCLUSIONS: The certainty of evidence was low for blood loss, pain and range of motion, and very low for transfusion rate, function, total adverse events and withdrawals from adverse events. We are uncertain whether cryotherapy improves transfusion rate, function, total adverse events or withdrawals from adverse events. We downgraded evidence for bias, indirectness, imprecision and inconsistency. Hence, the potential benefits of cryotherapy on blood loss, pain and range of motion may be too small to justify its use. More well-designed randomised controlled trials focusing especially on clinically meaningful outcomes, such...
Source: Cochrane Database of Systematic Reviews - September 14, 2023 Category: General Medicine Authors: Ashwin Aggarwal Sam Adie Ian A Harris Justine Naylor Source Type: research

Endoscopic Necrosectomy
Gastrointest Endosc Clin N Am. 2023 Oct;33(4):709-724. doi: 10.1016/j.giec.2023.04.010. Epub 2023 Jun 1.ABSTRACTThe management of walled-off necrosis has evolved substantially over the past 23 years since its first description. In this article, we review its history and the evidence supporting modern treatment, which is still subject to heterogeneity across centers and among endoscopists. This allows for creativity and customization of what can be an endoscopic marathon. Our typical practice is discussed with image and video guides aimed at improving procedure success.PMID:37709406 | DOI:10.1016/j.giec.2023.04.010
Source: The Medical Clinics of North America - September 14, 2023 Category: General Medicine Authors: Andrew J Gilman Todd H Baron Source Type: research

Hernia Prevention: The Role of Technique and Prophylactic Mesh to Prevent Incisional Hernias
This article aims to critically summarize the use of surgical technique and prophylactic mesh augmentation during fascial closure to inform decision-making and reduce incisional hernia formation.PMID:37709391 | DOI:10.1016/j.suc.2023.04.021
Source: The Medical Clinics of North America - September 14, 2023 Category: General Medicine Authors: Noah DeAngelo Arielle J Perez Source Type: research

Endoscopic Necrosectomy
Gastrointest Endosc Clin N Am. 2023 Oct;33(4):709-724. doi: 10.1016/j.giec.2023.04.010. Epub 2023 Jun 1.ABSTRACTThe management of walled-off necrosis has evolved substantially over the past 23 years since its first description. In this article, we review its history and the evidence supporting modern treatment, which is still subject to heterogeneity across centers and among endoscopists. This allows for creativity and customization of what can be an endoscopic marathon. Our typical practice is discussed with image and video guides aimed at improving procedure success.PMID:37709406 | DOI:10.1016/j.giec.2023.04.010
Source: The Medical Clinics of North America - September 14, 2023 Category: General Medicine Authors: Andrew J Gilman Todd H Baron Source Type: research

Hernia Prevention: The Role of Technique and Prophylactic Mesh to Prevent Incisional Hernias
This article aims to critically summarize the use of surgical technique and prophylactic mesh augmentation during fascial closure to inform decision-making and reduce incisional hernia formation.PMID:37709391 | DOI:10.1016/j.suc.2023.04.021
Source: The Medical Clinics of North America - September 14, 2023 Category: General Medicine Authors: Noah DeAngelo Arielle J Perez Source Type: research

Endoscopic Necrosectomy
Gastrointest Endosc Clin N Am. 2023 Oct;33(4):709-724. doi: 10.1016/j.giec.2023.04.010. Epub 2023 Jun 1.ABSTRACTThe management of walled-off necrosis has evolved substantially over the past 23 years since its first description. In this article, we review its history and the evidence supporting modern treatment, which is still subject to heterogeneity across centers and among endoscopists. This allows for creativity and customization of what can be an endoscopic marathon. Our typical practice is discussed with image and video guides aimed at improving procedure success.PMID:37709406 | DOI:10.1016/j.giec.2023.04.010
Source: The Medical Clinics of North America - September 14, 2023 Category: General Medicine Authors: Andrew J Gilman Todd H Baron Source Type: research

Hernia Prevention: The Role of Technique and Prophylactic Mesh to Prevent Incisional Hernias
This article aims to critically summarize the use of surgical technique and prophylactic mesh augmentation during fascial closure to inform decision-making and reduce incisional hernia formation.PMID:37709391 | DOI:10.1016/j.suc.2023.04.021
Source: The Medical Clinics of North America - September 14, 2023 Category: General Medicine Authors: Noah DeAngelo Arielle J Perez Source Type: research

Diabetes and non-alcoholic fatty liver disease: a bittersweet symphony
Med J Aust. 2023 Sep 12. doi: 10.5694/mja2.52106. Online ahead of print.NO ABSTRACTPMID:37700569 | DOI:10.5694/mja2.52106
Source: Med J Aust - September 13, 2023 Category: General Medicine Authors: Daniel Clayton-Chubb Stuart K Roberts Source Type: research

Chronic illness and psychopathology in emerging adults: Moderation by parent-child relationship quality
DISCUSSION: The emerging adults who reported the most psychological problems also reported having a health condition, low physical quality of life, and low maternal relationship quality, highlighting that the combination of these variables predicted the highest rate of psychological problems. A low maternal relationship quality contributes to poor psychological adjustment while a high maternal relationship quality contributes to good psychological adjustment.PMID:37700608 | DOI:10.1177/17423953231200681
Source: Chronic Illness - September 13, 2023 Category: General Medicine Authors: Abigail Kukay Cliff McKinney Source Type: research

Urban-rural disparities in suicide-related mortality trends among young adults (aged 25 to 44) in the United States, 1999-2020
Am J Med Sci. 2023 Sep 11:S0002-9629(23)01331-9. doi: 10.1016/j.amjms.2023.09.006. Online ahead of print.NO ABSTRACTPMID:37704168 | DOI:10.1016/j.amjms.2023.09.006
Source: The American Journal of the Medical Sciences - September 13, 2023 Category: General Medicine Authors: Muhammad Ali Tariq Aeman Asrar Minhail Khalid Malik Hamza Amin Source Type: research

Chronic illness and psychopathology in emerging adults: Moderation by parent-child relationship quality
DISCUSSION: The emerging adults who reported the most psychological problems also reported having a health condition, low physical quality of life, and low maternal relationship quality, highlighting that the combination of these variables predicted the highest rate of psychological problems. A low maternal relationship quality contributes to poor psychological adjustment while a high maternal relationship quality contributes to good psychological adjustment.PMID:37700608 | DOI:10.1177/17423953231200681
Source: Chronic Illness - September 13, 2023 Category: General Medicine Authors: Abigail Kukay Cliff McKinney Source Type: research

Higher versus lower fractions of inspired oxygen or targets of arterial oxygenation for adults admitted to the intensive care unit
CONCLUSIONS: In adult ICU patients, it is still not possible to draw clear conclusions about the effects of higher versus lower oxygenation strategies on all-cause mortality, SAEs, quality of life, lung injuries, myocardial infarction, stroke, and sepsis at maximum follow-up. This is due to low or very low-certainty evidence.PMID:37700687 | DOI:10.1002/14651858.CD012631.pub3
Source: Cochrane Database of Systematic Reviews - September 13, 2023 Category: General Medicine Authors: Thomas L Klitgaard Olav L Schj ørring Frederik M Nielsen Christian S Meyhoff Anders Perner J ørn Wetterslev Bodil S Rasmussen Marija Barbateskovic Source Type: research

Antioxidant vitamin and mineral supplements for slowing the progression of age-related macular degeneration
CONCLUSIONS: Moderate-certainty evidence suggests that antioxidant vitamin and mineral supplementation (AREDS: vitamin C, E, beta-carotene, and zinc) probably slows down progression to late AMD. People with intermediate AMD have a higher chance of benefiting from antioxidant supplements because their risk of progression is higher than people with early AMD. Although low-certainty evidence suggested little effect with lutein/zeaxanthin alone compared with placebo, exploratory subgroup analyses from one large American study support the view that lutein/zeaxanthin may be a suitable replacement for the beta-carotene used in th...
Source: Cochrane Database of Systematic Reviews - September 13, 2023 Category: General Medicine Authors: Jennifer R Evans John G Lawrenson Source Type: research

Higher versus lower fractions of inspired oxygen or targets of arterial oxygenation for adults admitted to the intensive care unit
CONCLUSIONS: In adult ICU patients, it is still not possible to draw clear conclusions about the effects of higher versus lower oxygenation strategies on all-cause mortality, SAEs, quality of life, lung injuries, myocardial infarction, stroke, and sepsis at maximum follow-up. This is due to low or very low-certainty evidence.PMID:37700687 | PMC:PMC10498149 | DOI:10.1002/14651858.CD012631.pub3
Source: Cochrane Database of Systematic Reviews - September 13, 2023 Category: General Medicine Authors: Thomas L Klitgaard Olav L Schj ørring Frederik M Nielsen Christian S Meyhoff Anders Perner J ørn Wetterslev Bodil S Rasmussen Marija Barbateskovic Source Type: research

Fibroblast growth factor 5 expression predicts the progression of oral squamous cell carcinoma
CONCLUSION: FGF5 can be induced by cellular stress and risk factors of OSCC, where high expression levels of FGF5 is potentially a useful parameter for predicting OSCC progression and patient survival.PMID:37704482 | DOI:10.1016/j.jfma.2023.08.020
Source: J Formos Med Assoc - September 13, 2023 Category: General Medicine Authors: Wan-Yi Shie Shih-Jung Cheng Kuan-Chi Chen Ching-Chun Tang Hsin-Hui Peng Hui-Hsin Ko Hsin-Han Hou Han-Yi Elizabeth Chou Source Type: research