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Total 416 results found since Jan 2013.
High-degree and broad-spectrum resistance mediated by a combination of NIb siRNA and miRNA suppresses replication of necrotic and common strains of potato virus Y
In this study, we designed specific siRNAs and miRNAs to target two regions of the PVYO replicase gene (NIb). Eight plant expression vectors containing one or two sRNAs were constructed. Luciferase activity assays showed that the designed sRNAs successfully cleaved theNIb gene of PVYO and PVYN, and the vector carrying a combined siRNA- and miRNA-based short hairpin RNA (shRNA) demonstrated the strongest inhibitory effect. These effects were confirmed through the acquisition of PVYO and PVYN resistance in transgenic sRNA-expressingNicotiana tabacum plants. This phenomenon could be related to a plant defense mechanism in whi...
Source: Archives of Virology - August 10, 2018 Category: Virology Source Type: research
GSE100589 Gene expression profiling of SAS cell line transfected with siRNA targeting CYLD
Contributors : Satoru Shinriki ; Hirofumi JonoSeries Type : Expression profiling by arrayOrganism : Homo sapiensOral squamous cell carcinoma (OSCC) has a very poor prognosis due to its highly invasive nature, and 5-year survival rate has not changed apparently for the past 30 years. Although cylindromatosis (CYLD) is thought as a potent tumor suppressor, its biological and clinical significances in OSCC are largely unknown. The aim of this study was to clarify roles of CYLD in OSCC progression. Our immunohistochemical analyses revealed that CYLD expression was significantly reduced at invasive lesions in OSCC tissues where...
Source: GEO: Gene Expression Omnibus - June 29, 2017 Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research
itrac, LLC Completes Multiple Acquisitions, Creating Leading Outsourced Dental Marketing, MarTech, and Recruiting Platform
NEWS PROVIDED BYitrac, LLC, May 26, 2022, 07:00 ETTAMPA, Fla., May 26, 2022 /PRNewswire/ -- itrac, LLC, a portfolio company of HealthEdge Investment Partners and 424 Capital, has expanded its product and service offering through the completion of three strategic add-on investments. With offices in Oregon, Texas, Indiana, Georgia, and Florida, itrac is one of the leading and longest-standing dental marketing agencies in the US, offering a suite of marketing technology ( " MarTech " ), outsourced marketing, training, and club software solutions to assist dentists and their practices ac...
Source: Dental Technology Blog - June 2, 2022 Category: Dentistry Source Type: news
Salespeople knowledge search behavior and sales performance: An investigation of printing equipment industry
This study investigates whether and how two learning styles – deep and surface – and two knowledge structures – vertical and horizontal – in respect of salespeople searching behavior in an inter-organizational information system lead to higher performance outcomes in printing equipment industry. We use a unique longitudinal dataset composed of 21,256 online search logs created by 408 salespeople and quarterly sales performance across 21 European countries from 2009 to 2013. The results show that salespeople must conduct a deep search to build rich product knowledge rather than surface search. Furthermore, instead o...
Source: Technological Forecasting and Social Change - January 11, 2017 Category: Science Source Type: research
Metacognitive computations for information search: Confidence in control.
Psychological Review, Vol 130(3), Apr 2023, 604-639; doi:10.1037/rev0000401The metacognitive sense of confidence can play a critical role in regulating decision making. In particular, a lack of confidence can justify the explicit, potentially costly, instrumental acquisition of extra information that might resolve uncertainty. Human confidence is highly complex, and recent computational work has suggested a statistically sophisticated tapestry behind the information that governs both the making and monitoring of choices. However, the consequences of the form of such confidence computations for search have yet to be underst...
Source: Psychological Review - February 9, 2023 Category: Psychiatry & Psychology Source Type: research
Changes in Search Path Complexity and Length During Learning of a Virtual Water Maze: Age Differences and Differential Associations with Hippocampal Subfield Volumes
In this study, we examined the association between volume of hippocampal subfields and age differences in virtual spatial navigation. In a sample of 65 healthy adults (age 19–75 years), advanced age was associated with a slower rate of improvement operationalized as shortening of the search path over 25 learning trials on a virtual Morris water maze task. The deficits were partially explained by greater complexity of older adults' search paths. Larger subiculum and entorhinal cortex volumes were associated with a faster decrease in search path complexity, which in turn explained faster shortening of search distance. ...
Source: Cerebral Cortex - May 16, 2016 Category: Neurology Authors: Daugherty, A. M., Bender, A. R., Yuan, P., Raz, N. Tags: Articles Source Type: research
Habitual attention in older and young adults.
Age-related decline is pervasive in tasks that require explicit learning and memory, but such reduced function is not universally observed in tasks involving incidental learning. It is unknown if habitual attention, involving incidental probabilistic learning, is preserved in older adults. Previous research on habitual attention investigated contextual cuing in young and older adults, yet contextual cuing relies not only on spatial attention but also on context processing. Here we isolated habitual attention from context processing in young and older adults. Using a challenging visual search task in which the probability o...
Source: Psychology and Aging - November 9, 2016 Category: Geriatrics Authors: Jiang, Yuhong V.; Koutstaal, Wilma; Twedell, Emily L. Source Type: research
Concept for automated computer-aided identification and evaluation of potentially non-compliant food products traded via electronic commerce
Publication date: March 2016 Source:Food Control, Volume 61 Author(s): Alexandra Krewinkel, Sebastian Sünkler, Dirk Lewandowski, Niklas Finck, Boris Tolg, Lothar W. Kroh, Georg A. Schreiber, Jan Fritsche The online marketplace for food products is continually expanding and all types of food and beverages can now be purchased over the internet. It is primarily the responsibility of the food business operator to ensure compliance with food safety law. However, the competent authorities are tasked with controlling the e-food sector as part of their regulatory duties to protect consumer health and to prevent fraud, ...
Source: Food Control - October 24, 2015 Category: Food Science Source Type: research
Sensors, Vol. 18, Pages 1189: Edge-Based Efficient Search over Encrypted Data Mobile Cloud Storage
ming Zhao
Smart sensor-equipped mobile devices sense, collect, and process data generated by the edge network to achieve intelligent control, but such mobile devices usually have limited storage and computing resources. Mobile cloud storage provides a promising solution owing to its rich storage resources, great accessibility, and low cost. But it also brings a risk of information leakage. The encryption of sensitive data is the basic step to resist the risk. However, deploying a high complexity encryption and decryption algorithm on mobile devices will greatly increase the burden of terminal operation and the difficul...
Source: Sensors - April 13, 2018 Category: Biotechnology Authors: Yeting Guo Fang Liu Zhiping Cai Nong Xiao Ziming Zhao Tags: Article Source Type: research
Educational Opportunity: “A Librarian’s Guide to NCBI” Bioinformatics Course
Send in Your Application to Participate in “A Librarian’s Guide to NCBI” Bioinformatics Course
Health science librarians in the United States are invited to participate in the next offering of the bioinformatics training course, “A Librarian’s Guide to NCBI,” sponsored by the National Library of Medicine (NLM), the National Center for Biotechnology Information (NCBI), and the National Network of Libraries of Medicine, NLM Training Center (NTC).
The course provides knowledge and skills for librarians interested in helping patrons use online molecular databases and tools from the NCBI....
Source: Dragonfly - October 27, 2014 Category: Databases & Libraries Authors: Carolyn Martin Tags: News from NLM Training & Education Source Type: news
Using guided inquiry and the information search process to develop research confidence among first year anatomy students
This article thoroughly describes the conceptualization, creation, improvement, implementation, and assessment of the projects beginning with version one, the Student Inquiry Projects. Following a pilot of the Student Inquiry Projects various evidence‐based improvements resulted in the final project version called the Inquiry Guided Learning Projects (IGLPs). A full assessment of the IGLPs revealed that students' self‐perceived confidence improved for all tested research skills including: research question development, research question selection, exploration of peer‐review literature, acquisition of resources, effec...
Source: Anatomical Sciences Education - April 22, 2015 Category: Anatomy Authors: Danielle Christine Bentley, Andrea Cristina Robinson, Robert Joseph Ruscitti Tags: Descriptive Article Source Type: research
Characterization of the global network of optical magnetometers to search for exotic physics (GNOME)
Publication date: Available online 24 October 2018Source: Physics of the Dark UniverseAuthor(s): S. Afach, D. Budker, G. DeCamp, V. Dumont, Z.D. Grujić, H. Guo, D.F. Jackson Kimball, T.W. Kornack, V. Lebedev, W. Li, H. Masia-Roig, S. Nix, M. Padniuk, C.A. Palm, C. Pankow, A. Penaflor, X. Peng, S. Pustelny, T. Scholtes, J.A. SmigaAbstractThe Global Network of Optical Magnetometers to search for Exotic physics (GNOME) is a network of geographically separated, time-synchronized, optically pumped atomic magnetometers that is being used to search for correlated transient signals heralding exotic physics. The GNOME is sensitive...
Source: Physics of the Dark Universe - October 24, 2018 Category: Physics Source Type: research
Smiths Group unveils Smiths Medical spinout plan, search for new CEO
Smith Medical parent company Smiths Group (LON:SMIN) today announced plans to pursue a demerger with its Smiths Medical business, which will become separately listed in the UK.
Smiths Group said it believes the demerger will strengthen both companies and allow the newly separated medical business to better capitalize on its leading positions, product launches and other value-creating opportunities. The company said it expects to complete the demerger some time during the first half of next year.
“Pursuing a demerger of Smiths Medical will lead to two stronger companies each focusing on accelerating the execution of...
Source: Mass Device - March 22, 2019 Category: Medical Devices Authors: Fink Densford Tags: Business/Financial News Featured Wall Street Beat Smiths Group plc Smiths Medical Source Type: news
Autofocus using adaptive prediction approximation combined search for the fluorescence microscope in second-generation DNA sequencing system
Autofocus is an important technique for high-speed image acquisition in the second-generation DNA sequencing system, and this paper studies the passive focus algorithm for the system, which consists of two parts: focus measurement (FM) and focus search (FS). Based on the properties of DNA ...
Source: Applied Optics - July 8, 2014 Category: Physics Authors: Hancong XuJinfeng LiuYang LiYan YinChenxu ZhuHua Lu Source Type: research
Research Byte: Expertise and individual differences: the search for the structure and acquisition of experts ’ superior performance via BrowZine
Expertise and individual differences: the search for the structure and acquisition of experts' superior performanceEricsson, K. AndersWiley Interdisciplinary Reviews: Cognitive Science: Articles in pressUniversity of Minnesota Users:http://login.ezproxy.lib.umn.edu/login?url=http://onlinelibrary.wiley.com/doi/10.1002/wcs.1382/pdfNon-University of Minnesota Users: (Full text may not be available)http://onlinelibrary.wiley.com/doi/10.1002/wcs.1382/pdfAccessed with BrowZine, supported by University of Minnesota.
Source: Intelligent Insights on Intelligence Theories and Tests (aka IQ's Corner) - December 3, 2016 Category: Neuroscience Source Type: blogs
