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Vaccination: Shingles (Herpes Zoster) Vaccine

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Total 272 results found since Jan 2013.

Locked-nucleotide antagonists to varicella zoster virus small non-coding RNA block viral growth and have potential as an anti-viral therapy
Antiviral Res. 2021 Jul 22:105144. doi: 10.1016/j.antiviral.2021.105144. Online ahead of print.ABSTRACTHerpes zoster (HZ) remains a significant health burden with millions of cases in North America and Europe annually. HZ is frequently followed by long-term pain or post-herpetic neuralgia (PHN). Although effective vaccines for HZ are available, currently used nucleotide analogues are often have limited effectiveness against HZ and especially PHN, so there remains a need for additional antiviral therapies for HZ. We recently identified a population of small non-coding RNA (sncRNA) encoded by Varicella Zoster Virus (VZV) and...
Source: Antiviral Research - July 25, 2021 Category: Virology Authors: Biswajit Das Punam Bisht Paul R Kinchington Ronald S Goldstein Source Type: research

A rare case of shingles after COVID-19 vaccine: is it a possible adverse effect?
Clin Exp Vaccine Res. 2021 May;10(2):198-201. doi: 10.7774/cevr.2021.10.2.198. Epub 2021 May 31.ABSTRACTCoronavirus disease 2019 (COVID-19) exhibit mild to moderate symptoms, whereas 15% of COVID-19 cases progress to pneumonia, some associated cutaneous findings are also reported as maculopapular eruptions, morbilliform rashes, urticaria, chickenpox-like lesions, and livedo reticularis. The inactivated COVID-19 vaccines are authorized for use in some countries including Turkey. Here, we report an unusual case of varicella-zoster virus (VZV) reactivation in a 68-year-old male patient who was vaccinated against COVID-19. The...
Source: Cell Research - July 5, 2021 Category: Cytology Authors: Saliha Bu şra Aksu G üzin Zeren Öztürk Source Type: research

People Are Reporting Unexpected Side Effects After COVID-19 Vaccination —But That’s Actually Normal
Abigail, a 29-year-old from New York City who asked to use a pseudonym to preserve her privacy, knew to expect some side effects after she got her second Pfizer-BioNTech COVID-19 vaccine in February. The fever, body aches and fatigue she felt were nothing surprising. But when she began experiencing heavy, “stupidly painful, debilitating” menstrual periods, she felt blindsided. “I had not heard a single person talking about it,” she says. While scientists have not confirmed that COVID-19 vaccines can cause menstrual changes like Abigail’s, she feels confident the shot was her trigger, since she...
Source: TIME: Health - April 22, 2021 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized COVID-19 Source Type: news

Molecules, Vol. 26, Pages 1132: Advances and Perspectives in the Management of Varicella-Zoster Virus Infections
eck Varicella-zoster virus (VZV), a common and ubiquitous human-restricted pathogen, causes a primary infection (varicella or chickenpox) followed by establishment of latency in sensory ganglia. The virus can reactivate, causing herpes zoster (HZ, shingles) and leading to significant morbidity but rarely mortality, although in immunocompromised hosts, VZV can cause severe disseminated and occasionally fatal disease. We discuss VZV diseases and the decrease in their incidence due to the introduction of live-attenuated vaccines to prevent varicella or HZ. We also focus on acyclovir, valacyclovir, and famciclovir (FDA app...
Source: Molecules - February 20, 2021 Category: Chemistry Authors: Graciela Andrei Robert Snoeck Tags: Review Source Type: research

Shingles of the eye can cause lasting vision impairment
Shingles, or herpes zoster, is a viral infection known for its characteristic painful, burning, or itchy rash. This rash appears along a particular affected nerve, for example in a band on one side of the chest or abdomen that extends around to the back. In fact, the name shingles comes from cingulum, the Latin word for girdle, belt, or sash. Shingles is caused by reactivation of the varicella zoster virus, the virus that causes chickenpox. After the initial chickenpox infection resolves the virus lives on in nerves all over the body, but is kept in check by the immune system. The risk of shingles therefore increases with ...
Source: Harvard Health Blog - January 27, 2021 Category: Consumer Health News Authors: Miriam Barshak, MD Tags: Eye Health Healthy Aging Vaccines Source Type: blogs

Shingles: What triggers this painful, burning rash?
If you’re like 95% of American adults, you had chickenpox as a kid. Before the United States started its widespread vaccination program in 1995, there were roughly four million cases of chickenpox every year. So, most people suffered through an infection with this highly contagious virus and its itchy, whole-body rash. But unlike many childhood viruses, the varicella-zoster virus that causes chickenpox doesn’t clear from the body when the illness ends. Instead it hangs around, taking up residence and lying dormant in the nerves, sometimes for decades, with the immune system holding it in check. In some people, it lives...
Source: Harvard Health Blog - December 14, 2020 Category: Consumer Health News Authors: Kelly Bilodeau Tags: Health Healthy Aging Skin and Hair Care Vaccines Source Type: blogs

Moderna Says Its COVID-19 Vaccine Is 94.5% Effective In Early Tests
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Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - November 16, 2020 Category: Consumer Health News Authors: CBS Boston Tags: Boston News Covid-19 Boston, MA Featured Healthcare Status Syndicated CBSN Boston Coronavirus Coronavirus Vaccine Moderna Moderna Therapeutics Source Type: news

Early Data Suggests Moderna ’s COVID-19 Vaccine Is Nearly 95% Effective—And You Can Keep It in the Fridge
For the second time this month, there’s promising news from a COVID-19 vaccine candidate: Moderna said Monday its shots provide strong protection, a dash of hope against the grim backdrop of coronavirus surges in the U.S. and around the world. Moderna said its vaccine appears to be 94.5% effective, according to preliminary data from the company’s still ongoing study. A week ago, competitor Pfizer Inc. announced its own COVID-19 vaccine appeared similarly effective — news that puts both companies on track to seek permission within weeks for emergency use in the U.S. Dr. Stephen Hoge, Moderna’s presid...
Source: TIME: Health - November 16, 2020 Category: Consumer Health News Authors: LAURAN NEERGAARD / AP Tags: Uncategorized COVID-19 News News Desk wire Source Type: news

Recombinant zoster vaccine (Shingrix ®): a new option for the prevention of herpes zoster and postherpetic neuralgia.
This article reviews the brief history, efficacy, and safety of the two vaccines and discusses the advantage of RZV over LZV based on the available literature. PMID: 32606264 [PubMed]
Source: Korean Journal of Pain - July 3, 2020 Category: Anesthesiology Tags: Korean J Pain Source Type: research

Fight Aging! Newsletter, May 25th 2020
In conclusion, our results suggest a previously unknown mechanism whereby the canonical NF-κB cascade and a mitochondrial fission pathway interdependently regulate endothelial inflammation. Lin28 as a Target for Nerve Regeneration https://www.fightaging.org/archives/2020/05/lin28-as-a-target-for-nerve-regeneration/ Researchers here show that the gene Lin28 regulates axon regrowth. In mice, raised levels of Lin28 produce greater regeneration of nerve injuries. Past research has investigated Lin28 from the standpoint of producing a more general improvement in regenerative capacity. It improves mitochondri...
Source: Fight Aging! - May 24, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Some healthcare can safely wait (and some can ’t)
Among the many remarkable things that have happened since the COVID-19 pandemic began is that a lot of our usual medical care has simply stopped. According to a recent study, routine testing for cervical cancer, cholesterol, and blood sugar is down nearly 70% across the country. Elective surgeries, routine physical examinations, and other screening tests have been canceled or rescheduled so that people can stay at home, avoid being around others who might be sick, and avoid unknowingly spreading the virus. Many clinics, hospitals, and doctors’ offices have been closed for weeks except for emergencies. Even if these facil...
Source: Harvard Health Blog - May 20, 2020 Category: Consumer Health News Authors: Robert H. Shmerling, MD Tags: Health Health care Healthy Aging Men's Health Women's Health Source Type: blogs