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The False Choice Between Science And Economics
This article originally appeared on The Bulwark here. The post The False Choice Between Science And Economics appeared first on The Health Care Blog.
Source: The Health Care Blog - May 1, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Health Policy David Shaywitz Source Type: blogs

Vaccines, Antibodies and Drug Libraries. The Possible COVID-19 Treatments Researchers Are Excited About
In early April, about four months after a new, highly infectious coronavirus was first identified in China, an international group of scientists reported encouraging results from a study of an experimental drug for treating the viral disease known as COVID-19. It was a small study, reported in the New England Journal of Medicine, but showed that remdesivir, an unapproved drug that was originally developed to fight Ebola, helped 68% of patients with severe breathing problems due to COVID-19 to improve; 60% of those who relied on a ventilator to breathe and took the drug were able to wean themselves off the machines after 18...
Source: TIME: Health - April 14, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news

All Your Coronavirus Questions, Answered
One of the worst symptoms of any plague is uncertainty—who it will strike, when it will end, why it began. Merely understanding a pandemic does not stop it, but an informed public can help curb its impact and slow its spread. It can also provide a certain ease of mind in a decidedly uneasy time. Here are some of the most frequently asked questions about the COVID-19 pandemic from TIME’s readers, along with the best and most current answers science can provide. A note about our sourcing: While there are many, many studies underway investigating COVID-19 and SARS-CoV-19, the novel coronavirus that causes the illn...
Source: TIME: Health - April 14, 2020 Category: Consumer Health News Authors: TIME Staff Tags: Uncategorized COVID-19 Explainer Source Type: news

CORR Insights ®: Influenza Vaccination Is Not Associated with Increased Number of Visits for Shoulder Pain.
CORR Insights®: Influenza Vaccination Is Not Associated with Increased Number of Visits for Shoulder Pain. Clin Orthop Relat Res. 2020 Apr 14;: Authors: Sohn DH PMID: 32301799 [PubMed - as supplied by publisher]
Source: Clinical Orthopaedics and Related Research - April 13, 2020 Category: Orthopaedics Authors: Sohn DH Tags: Clin Orthop Relat Res Source Type: research

Influenza Vaccination Is Not Associated with Increased Number of Visits for Shoulder Pain.
CONCLUSIONS: Shoulder symptoms sufficient to seek care are notably common, even among relatively young adults, and are not more common after vaccination. Although this does not rule out an important rare pathology specific to vaccination, it seems important to consider the potential harms of assuming, based largely on chronology, that persistent shoulder pain after vaccination-something expected to be common based merely on the anticipated frequency of overlap of vaccination and common shoulder problems-represents harm from vaccine. LEVEL OF EVIDENCE: Level III, therapeutic study. PMID: 32141910 [PubMed - as supplied by publisher]
Source: Clinical Orthopaedics and Related Research - March 1, 2020 Category: Orthopaedics Authors: Gonzalez AI, Kortlever JTP, Moore MG, Ring DC Tags: Clin Orthop Relat Res Source Type: research

Post #47 How to Optimally Utilize Tamiflu
Every year in the United States, the CDC estimates that influenza results in between 9 million – 45 million illnesses, between 140,000 – 810,000 hospitalizations, and between 12,000 – 61,000 deaths (approximately 100  – 200 being pediatric fatalities). In the United States, the immense disease burden of the flu is unparalleled with any other pathogen, but fortunately there is a vaccine and antiviral medications which help to mitigate the yearly morbidity and mortality wrought by influenza.Because the flu changes its shape every year by a process called antigenic shift and drift, i...
Source: A Pediatrician's Blog - February 22, 2020 Category: Pediatrics Source Type: blogs

Janssen Announces Submission to U.S. FDA for New DARZALEX ® (Daratumumab)-Based Combination Regimen for Patients with Relapsed/Refractory Multiple Myeloma
RARITAN, NJ, February 10, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today the submission of a supplemental Biologics License Application (sBLA) to the U.S. Food and Drug Administration (FDA) seeking approval of DARZALEX® (daratumumab) in combination with Kyprolis® (carfilzomib) and dexamethasone (DKd) for relapsed/refractory multiple myeloma. The sBLA is supported by results from the Phase 3 CANDOR study, which compared treatment with DKd to carfilzomib and dexamethasone (Kd) in patients with multiple myeloma who relapsed after one to three prior lines of therapy. “While we contin...
Source: Johnson and Johnson - February 10, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Coronavirus: What parents should know and do
As a parent, you can’t help but worry about the safety of your children. So it’s natural that as stories about the novel coronavirus that started in China flood the news, parents worry about whether their children could be at risk. We are still learning about this new virus; there is much we do not know yet about how it spreads, how serious it can be, or how to treat it. The fact that so much is unknown is a big part of what makes it frightening. But there are things we do know — about this virus and other similar viruses — that can help us keep our children safe and well. All of the advice below assumes that you a...
Source: Harvard Health Blog - February 5, 2020 Category: Consumer Health News Authors: Claire McCarthy, MD Tags: Adolescent health Children's Health Infectious diseases Parenting Source Type: blogs

Comparison of the immunogenicity and safety of quadrivalent and tetravalent influenza vaccines in children and adolescents.
CONCLUSIONS: The immunogenicity of QIV for common ingredients was similar to that of TIV, but the former exhibited significantly higher immunogenicity for the unique lineage. QIV also had the same reliable safety as TIV. PMID: 31948819 [PubMed - as supplied by publisher]
Source: Vaccine - January 12, 2020 Category: Allergy & Immunology Authors: Huang C, Fu X, Zhou Y, Mi F, Tian G, Liu X, Wu J, Ding C, Yan D, Li L, Yang S Tags: Vaccine Source Type: research

56-year-old woman • worsening pain in left upper arm • influenza vaccination in the arm a few days prior to pain onset • Dx?
Abstract Worsening pain in left upper arm. Pain worsens with movement-especially abduction. Influenza vaccination in the arm a few days prior to pain onset. Dx? PMID: 32017838 [PubMed - in process]
Source: The Journal of Family Practice - December 31, 2019 Category: Practice Management Authors: Farford B Tags: J Fam Pract Source Type: research

Brand-Specific Enhanced Safety Surveillance of GSK ’s Quadrivalent Seasonal Influenza Vaccine in Belgium, Germany and Spain for the 2018/2019 Season
ConclusionIn compliance with EMA guidance, this study design allowed for near real-time assessment of AEs. No safety signals were detected at any point during the study period. The study supports and confirms the acceptable safety profile of GSK ’s IIV4.ClinicalTrials.gov identifierNCT03688620.
Source: Drug Safety - December 27, 2019 Category: Drugs & Pharmacology Source Type: research

Immunogenicity and safety of Quadrivalent Influenza HA vaccine in Indonesian children: An open-labeled, bridging, clinical study.
CONCLUSION: The investigational QIV was immunogenic with an acceptable safety profile in children 6 months to 8 years of age. CLINICAL TRIAL REGISTRATION: NCT03336593. PMID: 31862195 [PubMed - as supplied by publisher]
Source: Vaccine - December 16, 2019 Category: Allergy & Immunology Authors: Dhamayanti M, Tarigan R, Fadlyana E, Prasetyo D, Amalia N, Rusmil VK, Sari RM, Bachtiar NS, Rusmil K, Kartasasmita CB Tags: Vaccine Source Type: research

Reports of atypical shoulder pain and dysfunction following inactivated influenza vaccine, Vaccine Adverse Event Reporting System (VAERS), 2010-2017.
CONCLUSIONS: Reports of atypical shoulder pain and dysfunction following IIV were uncommon, considering the amount of IIV use, and stable across influenza seasons. While specific etiology of cases is unknown, improperly administered vaccine, which is preventable, might be a factor. Prevention strategies include education, training, and adherence to best practices for vaccine administration. PMID: 31784231 [PubMed - as supplied by publisher]
Source: Vaccine - November 25, 2019 Category: Allergy & Immunology Authors: Hibbs BF, Ng CS, Museru O, Moro PL, Marquez P, Woo EJ, Cano MV, Shimabukuro TT Tags: Vaccine Source Type: research

Shoulder Injury Related to Vaccine Administration (SIRVA): Petitioner claims to the National Vaccine Injury Compensation Program, 2010-2016.
CONCLUSIONS: Most conceded claims for SIRVA were in women and involved influenza vaccines. Injection too high on the arm could be a factor due to the risk of injecting into underlying non-muscular tissues. Healthcare providers should be aware of proper injection technique and anatomical landmarks when administering vaccines. PMID: 31771864 [PubMed - as supplied by publisher]
Source: Vaccine - November 22, 2019 Category: Allergy & Immunology Authors: Hesse EM, Atanasoff S, Hibbs BF, Adegoke OJ, Ng C, Marquez P, Osborn M, Su JR, Moro PL, Shimabukuro T, Nair N Tags: Vaccine Source Type: research

Respiratory Virus Infections in People Over 14 Years of Age in Poland in the Epidemic Season of 2017/18.
In this study we demonstrate the results of examination of 4,507 people aged over 14 years toward the influenza infection in the epidemic season of 2017/18. Most of the confirmed infections were reported in older people aged over 65, a high-risk population group. A low percentage of the vaccinated population may affect an increased number of confirmed influenza viruses in the elderly. The findings demonstrate a need to increase awareness of vaccination benefits, which is particularly essential to avoid influenza infection in the elderly. PMID: 31559569 [PubMed - as supplied by publisher]
Source: Advances in Experimental Medicine and Biology - September 28, 2019 Category: Research Tags: Adv Exp Med Biol Source Type: research