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The Attenuation of Pain Behavior and Serum COX-2 Concentration by Curcumin in a Rat Model of Neuropathic Pain.
CONCLUSIONS: A considerable decline in pain behavior and serum COX-2 levels was seen in rat following administration of curcumin in CCI model of neuropathic pain. High concentration of Curcumin was able to reduce the chronic neuropathic pain induced by CCI model and the serum level of COX-2.
PMID: 25031810 [PubMed]
Source: Korean Journal of Pain - December 1, 2015 Category: Anesthesiology Tags: Korean J Pain Source Type: research
Looking for Beauty in a Life of Chronic Pain
Winter seems to be the time of year we’re all worn from the mere act of survival. We feel like worn out human popsicles as we’ve rediscovered the very acts of staying warm and moving around seem too much to expect. Maybe those bears that hibernate have the right idea. It would be sweet to go to sleep and wake up when it’s spring but alas, it’s not to be for us mere humans. We are imbibed with the tasks of survival, family responsibilities and dragging ourselves along for the ride. I think most of us feel we used to be more appreciative of winter, you know BEFORE. That would be before pain arrived in our lives. We r...
Source: Life with Chronic Pain - March 7, 2013 Category: Other Conditions Authors: admin Tags: Chronic pain lifestyle beauty coping with chronic pain Source Type: blogs
“I Hate You Chronic Pain!”
There are some days in this way of life one just has to speak the ugly side of truth. It’s isn’t always pretty. I sometimes believe after the many years I’ve been writing this blog, some of my readers think I’m Little Mary Sunshine ; I assure you, I am not.
We often find ourselves in one particularly pitiable state I like to call, “My life is worse than your life.” It’s only human of us to feel that way but it is most definitely a dead end road but a path we occasionally drive down. Life is hard enough for the jolly and the totally healthy but for those of us who face pain each day of our lives, usually in ...
Source: Life with Chronic Pain - February 14, 2013 Category: Other Conditions Authors: Sue Falkner-Wood Tags: Pain Management chronic pain and emotional health chronic pain and forgiveness Source Type: blogs
The antinociceptive effect of artemisinin on the inflammatory pain and role of GABAergic and opioidergic systems.
Conclusions: It seems that antinocicptive effects of artemisinin are mediated by GABAA receptors.
PMID: 31257824 [PubMed]
Source: Korean Journal of Pain - July 2, 2019 Category: Anesthesiology Tags: Korean J Pain Source Type: research
“I Hate You Chronic Pain!”
There are some days in this way of life one just has to speak the ugly side of truth. It’s isn’t always pretty. I sometimes believe after the many years I’ve been writing this blog, some of my readers think I’m Little Mary Sunshine ; I assure you, I am not.
We often find ourselves in one particularly pitiable state I like to call, “My life is worse than your life.” It’s only human of us to feel that way but it is most definitely a dead end road but a path we occasionally drive down. Life is hard enough for the jolly and the totally healthy but for those of us who face pain each day of our lives, usually in ...
Source: Life with Chronic Pain - February 14, 2013 Category: Other Conditions Authors: admin Tags: Emotional Health chronic pain and emotional health chronic pain and forgiveness Source Type: blogs
Medicinal Plants of the Family Lamiaceae in Pain Therapy: A Review.
In this study, the analgesic activity, possible active compounds of Lamiaceae genus, and also the possible mechanism of actions of these plants are presented. The data highlighted in this review paper provide valuable scientific information for the specific implications of Lamiaceae plants in pain modulation that might be used for isolation of potentially active compounds from some of these medicinal plants in future and formulation of commercial therapeutic agents.
PMID: 29854039 [PubMed - in process]
Source: Pain Research and Management - June 3, 2018 Category: Anesthesiology Authors: Uritu CM, Mihai CT, Stanciu GD, Dodi G, Alexa-Stratulat T, Luca A, Leon-Constantin MM, Stefanescu R, Bild V, Melnic S, Tamba BI Tags: Pain Res Manag Source Type: research
Effect of Zhongyi paste on inflammatory pain in mice by regulation of the extracellular regulated protein kinases 1/2-cyclooxygenase-2-prostaglandin E2 pathway.
Conclusions: Our results indicated that Zhongyi paste is a very effective drug to reduce inflammatory swelling of the foot, and its mechanism of action is related to regulation of the ERK1/2-COX-2-PGE2 pathway.
PMID: 32989198 [PubMed]
Source: Korean Journal of Pain - October 1, 2020 Category: Anesthesiology Tags: Korean J Pain Source Type: research
Antinociceptive effect of intrathecal sec-O-glucosylhamaudol on the formalin-induced pain in rats.
CONCLUSIONS: These results demonstrate that intrathecal SOG has a very strong antinociceptive effect in the formalin test and it seems the effect is related to an opioid receptor.
PMID: 28416993 [PubMed - in process]
Source: Korean Journal of Pain - April 22, 2017 Category: Anesthesiology Tags: Korean J Pain Source Type: research
How Does Acute Pain Become Chronic? | NIH Director's Blog
Chronic pain is a major medical problem, affecting as many as 100 million Americans, robbing them of a full sense of well-being, disrupting their ability to work and earn a living, and causing untold suffering for the patient and family. This condition costs the country an estimated $560-635 billion annually—a staggering economic burden [1]. Worst of all, chronic pain is often resistant to treatment. NIH launched the Grand Challenge on Chronic Pain [2] to investigate how acute pain (which is part of daily experience) evolves into a chronic condition and what biological factors contribute to this transition.But you m...
Source: Psychology of Pain - September 26, 2013 Category: Psychiatrists and Psychologists Source Type: blogs
Conversations about cannabis for chronic pain
The debate about cannabis and derivatives for persistent pain continues to grow in New Zealand, and elsewhere in the world. Many people I’ve treated and who are living with persistent pain say they like to use cannabis (in a variety of forms) to help with pain intensity and sleep, adding their voices to those wanting “medicinal” cannabis to be approved. In the few patients I’ve worked with who have managed to obtain a cannabis product (in NZ it has to be legally prescribed and will generally be in the form of Sativex or similar) the effect doesn’t seem as profound as the real thing (whether sm...
Source: HealthSkills Weblog - August 6, 2017 Category: Anesthesiology Authors: adiemusfree Tags: Chronic pain Therapeutic approaches Research Pain conditions Coping strategies Science in practice Health healthcare biopsychosocial pain management Source Type: blogs
What Are The Best Natural Remedies That Help Relieve Your Joint Pain?
You're reading What Are The Best Natural Remedies That Help Relieve Your Joint Pain?, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles.
If you are among millions of people suffering from joint pain and arthritis and living on pain-killers for quite a while, there is good news for you-you can have natural remedies to get rid of your pain. Whether you are facing stiffness, reduced the range of movements, and difficulty walking, there are certain natural therapies that are pretty much safer alternatives to taking drugs.
Accor...
Source: PickTheBrain | Motivation and Self Improvement - January 8, 2019 Category: Consumer Health News Authors: smithwillas Tags: health and fitness Joint pain natural remedies Source Type: blogs
Natural Remedies That Help Relieve Your Joint Pain?
You're reading Natural Remedies That Help Relieve Your Joint Pain?, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles.
If you are among millions of people suffering from joint pain and arthritis and living on pain-killers for quite a while, there is good news for you-you can have natural remedies to get rid of your pain. Whether you are facing stiffness, reduced the range of movements, and difficulty walking, there are certain natural therapies that are pretty much safer alternatives to taking drugs.
According to the Centre...
Source: PickTheBrain | Motivation and Self Improvement - January 9, 2019 Category: Consumer Health News Authors: smithwillas Tags: health and fitness Joint pain natural remedies Source Type: blogs
Natural Remedies That Help Relieve Your Joint Pain
You're reading Natural Remedies That Help Relieve Your Joint Pain, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles.
If you are among millions of people suffering from joint pain and arthritis and living on pain-killers for quite a while, there is good news for you-you can have natural remedies to get rid of your pain. Whether you are facing stiffness, reduced the range of movements, and difficulty walking, there are certain natural therapies that are pretty much safer alternatives to taking drugs.
According to the Centre ...
Source: PickTheBrain | Motivation and Self Improvement - January 9, 2019 Category: Consumer Health News Authors: smithwillas Tags: health and fitness Joint pain natural remedies Source Type: blogs
Tibetan Herbal Pain-Relieving Plaster for Chronic Musculoskeletal Pain Among Cancer Survivors: Study Protocol of a Randomized, Double-Blind, Placebo-Controlled Trial
Front Pharmacol. 2022 May 4;13:878371. doi: 10.3389/fphar.2022.878371. eCollection 2022.ABSTRACTChronic pain is common and debilitating in cancer survivors. Tibetan herbal pain-relieving plaster is used as an external analgesic to treat musculoskeletal pain in China; however, its safety and efficacy have not been evaluated via clinical trials in cancer survivors. We designed this Phase II randomized, double-blind, placebo-controlled trial (ClinicalTrials.gov Identifier: NCT04916249) to assess the efficacy and safety of the pain-relieving plaster for temporary pain relief among cancer survivors with chronic musculoskeletal ...
Source: Pain Physician - May 23, 2022 Category: Anesthesiology Authors: Mingxiao Yang Raymond E Baser Susan Q Li Yen-Nien Hou Kamyar Chong Yi Lily Zhang Irfan Hoque Ting Bao Jun J Mao Source Type: research
