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Total 7706 results found since Jan 2013.

FDA approves Roche ’s Columvi, the first and only bispecific antibody with a fixed-duration treatment for people with relapsed or refractory diffuse large B-cell lymphoma
Pivotal study showed durable responses, with a 56% overall response rate, a 43% complete response (remission) rate and a median duration of response of 1.5 years (18.4 months)1Given over a fixed period of time,Columvi provides patients with a treatment end date and potential time off treatmentColumvi is part of Roche ' s industry-leading portfolio of T-cell engaging bispecific antibodies in non-Hodgkin lymphoma, which also includes the recently approvedLunsumioto treat follicular lymphomaBasel, 16 June 2023 – Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that the U.S. Food and Drug Administration (FDA) has approved ...
Source: Roche Media News - June 27, 2023 Category: Pharmaceuticals Source Type: news

Vagueness in Goals-of-Care Conferences for Critically Ill Patients: Types of Hedge Language Used by Physicians
CONCLUSIONS: Hedge language is ubiquitous in physician-surrogate communication during goals-of-care conferences in the ICU and can be used to introduce vagueness to statements in ways beyond expressing uncertainty. It is not known how hedge language impacts decision-making or clinician-surrogate interactions. This study prioritizes specific types of hedge language for future research based on their frequency and novelty.PMID:37358354 | DOI:10.1097/CCM.0000000000005974
Source: Pain Physician - June 26, 2023 Category: Anesthesiology Authors: Vaishali Mittal Nicholas A Hakes David Magnus Jason N Batten Source Type: research

Acupuncture in Addiction Medicine: Its History, Evidence, and Possibilities
This article is a narrative review of the background, the basic science and clinical research, and future direction of acupuncture in addiction medicine.PMID:37361008 | PMC:PMC10282830 | DOI:10.1089/acu.2023.0021
Source: Acupuncture in Medicine - June 26, 2023 Category: Complementary Medicine Authors: Jamie M Kitzman Laura C Bowman Yuan-Chi Lin Source Type: research

Sex differences in lifetime prevalence of low back pain: A multinational study of opposite ‐sex twin pairs
ConclusionsWe found no evidence of the association between sex and LBP in our merged sample. Between-population differences (i.e. cultural background or health system characteristics) are likely to be major factors leading to variation in the sex association with LBP when familial factors are accounted for.SignificanceOur study of adult opposite-sex twin pairs found no evidence of an association between female sex and lifetime prevalence of low back pain after controlling for familial factors in the merged sample from Australia, Spain and USA, contrary to findings from previous studies of unrelated individuals. Our finding...
Source: European Journal of Pain - June 26, 2023 Category: Anesthesiology Authors: Lucas Calais ‐Ferreira, Daniel Pozzobon, Marina B. Pinheiro, Fiona M. Blyth, Juan R. Ordoñana, Glen E. Duncan, John L. Hopper, Paulo H. Ferreira, Manuela L. Ferreira Tags: ORIGINAL ARTICLE Source Type: research

Geriatricians, general internists, and potentially inappropriate medications for a national sample of older adults
CONCLUSION: Findings suggest geriatricians in the United States prescribe PIMs at lower rates than general internists. This highlights the value geriatricians provide as well as opportunities to embed key principles of geriatric care into internal medicine training and health care delivery systems.PMID:37350649 | DOI:10.1111/jgs.18489
Source: Pain Physician - June 23, 2023 Category: Anesthesiology Authors: Jonathan L Vandergrift Weifeng Weng Bruce Leff Bradley M Gray Source Type: research

Professional Roles, Services, and Quality of Life for End-of-Life Doulas in the United States
End-of-life doulas provide support to the chronically ill, dying, and their families. However, little is known about the roles and services of doulas practicing in the United States.
Source: Journal of Pain and Symptom Management - June 23, 2023 Category: Palliative Care Authors: Amanda C. DeDiego, Feven Seifu, Ayn Rassier, Alyson Bartley, Andrea Ollila Tags: Brief Report Source Type: research

Chronic pain trials often exclude people with comorbid depressive symptoms: A secondary analysis of 346 randomized controlled trials
CONCLUSION: This study highlights opportunities to improve the conduct of chronic pain clinical trials. The majority of randomized controlled trials s analyzed evaluated participants without significant depressive symptoms at baseline, thus the findings synthesized in systematic reviews and subsequent guidelines are most applicable to the subset of real-world populations that do not have significant depressive symptoms. As well, systemic biases around psychological conditions and gender may be important contributors to differences in the study of depression in fibromyalgia compared with common conditions such as arthritis ...
Source: Clinical Trials - June 22, 2023 Category: Research Authors: Darren K Cheng Maarij Hannan Ullah Henry Gage Rahim Moineddin Abhimanyu Sud Source Type: research

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