SGLT2 Inhibitors Begin to Show Potential in Rheumatology SGLT2 Inhibitors Begin to Show Potential in Rheumatology
Sodium-glucose cotransporter-2 inhibitors are not approved to treat gout, lupus, or lupus nephritis, but clinicians are uncovering signs of benefits in these conditions.MDedge News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - January 8, 2024 Category: Endocrinology Tags: Rheumatology Source Type: news

The Most Exciting New Advancements in Managing and Treating Lupus
The case study involved just one patient: a 20-year-old woman with severe systemic lupus erythematosus (SLE). But the study’s results were so dramatic that they appeared in 2021 in the New England Journal of Medicine.  The woman received a type of cell therapy called CAR-T, which in the past has been used primarily to treat cancer. CAR-T cell therapy involves altering a patient’s immune cells so that they identify and attack problems or pathogens. In people with cancer, that attack is aimed at the diseased cells. But in the NEJM case study, the therapy was directed at the woman’s own B cells,...
Source: TIME: Health - December 27, 2023 Category: Consumer Health News Authors: Markham Heid Tags: Uncategorized healthscienceclimate Source Type: news

Obinutuzumab Preserves Kidney Function in Lupus Nephritis
THURSDAY, Nov. 16, 2023 -- For patients with lupus nephritis (LN), obinutuzumab treatment results in better preservation of kidney function and prevention of LN flares, according to a study published online Nov. 10 in Arthritis&... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 16, 2023 Category: Pharmaceuticals Source Type: news

B-Cell Depletion Helps Maintain Kidney Function in Lupus Nephritis
(MedPage Today) -- SAN DIEGO -- Treatment with the B-cell depleting agent obinutuzumab (Gazyva) helped patients with lupus nephritis avoid the most serious adverse outcomes, according to a post hoc analysis of randomized trial data. Among 125... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - November 10, 2023 Category: Rheumatology Source Type: news

Obinutuzumab Promotes Renal Preservation in Lupus Nephritis Obinutuzumab Promotes Renal Preservation in Lupus Nephritis
A post hoc analysis of the NOBILITY trial showed improved outcomes for patients taking obinutuzumab (Gazyva) compared with placebo.Medscape Medical News (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - November 10, 2023 Category: Allergy & Immunology Tags: Rheumatology News Source Type: news

Urine Test Biomarker Allows Diagnosis Without Kidney Biopsy Urine Test Biomarker Allows Diagnosis Without Kidney Biopsy
Patients with acute tubulointerstitial nephritis show high levels of the protein CXCL9 in urine, potentially allowing for diagnosis without the need for a kidney biopsy.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 31, 2023 Category: Consumer Health News Tags: Nephrology News Source Type: news

Voclosporin Safe, Effective for Long-Term Treatment of Lupus Nephritis
WEDNESDAY, July 26, 2023 -- Voclosporin can preserve kidney function up to three years for patients with lupus nephritis, according to a study published online July 19 in Arthritis& Rheumatology. Amit Saxena, M.D., from New York University in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 26, 2023 Category: Pharmaceuticals Source Type: news

S2 Episode 2: Is It Lupus Nephritis? A Path to Diagnosis and Treatment S2 Episode 2: Is It Lupus Nephritis? A Path to Diagnosis and Treatment
Join experts Drs Matt Sparks and Dawn Caster as they discuss the complexities around the management of lupus nephritis. What tools do we have now? What ' s on the horizon? Tune in to find out.Medscape (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 25, 2023 Category: Consumer Health News Tags: Nephrology InDiscussion Source Type: news

New Study Shows Intestinal Bacteria May Trigger Lupus Flare-Ups In Women
A recent study by revealed a link between bacterial blooms of the gut bacterium Ruminococcus blautia gnavus and flare-ups of disease in women with Lupus Nephritis. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - July 6, 2023 Category: Pharmaceuticals Authors: William A. Haseltine, Contributor Tags: Healthcare /healthcare Innovation /innovation business pharma & standard Source Type: news

Unknown criminals for kidney: acute interstitial nephritis due to lavender tea - Ozer H, Sayan ZA, Baloglu I, Ozturk Y, Yonet F, Turkmen K.
INTRODUCTION: Spanish Lavender is an herbal from the lavender family and is widely used among people for the belief that it cures various diseases. Acute interstitial nephritis (AIN) is one of the common causes of acute kidney injury (AKI). Although drugs ... (Source: SafetyLit)
Source: SafetyLit - July 4, 2023 Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news

Gut Microbiome Instability Associated With Lupus Nephritis Flares
(MedPage Today) -- A certain type of intestinal microflora may be a trigger for lupus nephritis flares, researchers found. Serial fecal samples from 16 women with systemic lupus erythematosus (SLE), taken over periods ranging from 6 months to... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - June 27, 2023 Category: Gastroenterology Source Type: news

Strategies Evolve for B-Cell Depletion in Lupus Nephritis Strategies Evolve for B-Cell Depletion in Lupus Nephritis
Growing evidence suggests more complete B-cell depletion in patients with lupus nephritis is associated with a greater likelihood of treatment response.MDedge News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 16, 2023 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Lupus Nephritis: Hopes, Questions Arise for Baricitinib Lupus Nephritis: Hopes, Questions Arise for Baricitinib
Results from a small, independently funded, double-blind, active-comparator trial suggest that baricitinib could be beneficial in the treatment of lupus nephritis.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 1, 2023 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Early Remission in Lupus Nephritis May Not Bar Advanced CKD Early Remission in Lupus Nephritis May Not Bar Advanced CKD
Patients with lupus nephritis who achieve complete remission within 1 year of starting treatment can still develop advanced chronic kidney disease within a few years.MDedge News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 23, 2023 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Lupus Nephritis Treatment Response Biomarkers Gain Ground Lupus Nephritis Treatment Response Biomarkers Gain Ground
A panel of protein biomarkers in urine could achieve better identification of lupus nephritis patients who are likely to respond to treatment.MDedge News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 19, 2023 Category: Consumer Health News Tags: Rheumatology News Source Type: news