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Total 31 results found since Jan 2013.

A Comparative Study of the Resorption and Immune Response for Two Starch-Based Hemostat Powders
Powder hemostats are valuable adjuncts to minimize intraoperative and postoperative complications. In addition to promotion of rapid coagulation, resorption, and biocompatibility are desirable attributes. Plant starch-based polysaccharide hemostat powders are effective and widely used hemostatic agents, however their source and/or processing can affect characteristics such as in  vivo degradability. For example, Arista is a purified/hydrolyzed starch powder that is rapidly resorbed in vivo; whereas PerClot shows slow resorption and preservation of a crystalline form.
Source: Journal of Surgical Research - October 31, 2022 Category: Surgery Authors: H éctor Capella-Monsonís, Arthi Shridhar, Bharadwaj Chirravuri, Matthew Figucia, Greg Learn, Keith Greenawalt, Stephen F. Badylak Tags: Acute Care Surgery Source Type: research

Hemostatic Efficacy and Biocompatibility Evaluation of a Novel Absorbable Porous Starch Hemostat
CONCLUSION: According to our study, Ca2+CPSM could effectively achieve hemostasis in the standard rat liver injury model and exhibited good blood compatibility and in vivo tissue compatibility. These finding suggested that Ca2+CPSM as a new kind of APSH had its extensive clinical application value.PMID:34551638 | DOI:10.1177/15533506211046100
Source: Surgical Innovation - September 23, 2021 Category: Surgery Authors: Jianjun Zhu Zhuona Wu Wenzhong Sun Zhiyun Meng Xiaoxia Zhu Hui Gan Ruolan Gu Xuan Guo Guifang Dou Source Type: research

Comparison of hemostatic efficacy of topical Ankaferd Blood Stopper on heparinized and nonheparinized rats in bleeding related to liver injury.
CONCLUSIONS: Ankaferd Blood Stopper can be safely and effectively used in surgical practice and in patients with additional diseases requiring heparinization, since it causes minimal reaction in the liver and decreases the amount of bleeding especially in the heparinized group. PMID: 33533829 [PubMed - as supplied by publisher]
Source: Acta Cirurgica Brasileira - February 4, 2021 Category: Surgery Authors: Ergin M, Özer N Tags: Acta Cir Bras Source Type: research

Association between intraoperative application of microfibrillar collagen hemostat and anastomotic leakage after anterior resection for rectal cancer: A retrospective case-control study
The purpose of the study is to evaluate the association between microfibrillar collagen hemostat and anastomotic leakage after anterior resection.
Source: Surgery - November 4, 2020 Category: Surgery Authors: Meng Kong, Hongyuan Chen, Yugang Jiang, Yingying Xin, Yue Han, Hongguang Sheng Source Type: research

Evaluation of the Hemostatic Efficacy of Two Powdered Topical Absorbable Hemostats Using a Porcine Liver Abrasion Model of Mild to Moderate Bleeding.
CONCLUSION: Surgicel-P provided more effective and sustained hemostasis and faster TTH than Hemoblast-B. Surgicel-P represents a novel clinical alternative to provide adjunctive control of diffuse mild and moderate bleeding. Surgicel-P combines an ORC powder formulation and a delivery system in a device that is particularly useful for application on large surfaces and difficult-to-access anatomical locations where application of other forms of topical hemostats may be impractical. PMID: 32928005 [PubMed - as supplied by publisher]
Source: Journal of Investigative Surgery - September 18, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Cover Image
On the Cover: Right ankle, anterolateral viewing portal, patient supine under dry conditions: chondral plugs are introduced with a hemostat through the anteromedial portal with the foot maintained in plantarflexion using an ankle distractor. Plugs are placed from posterior to anterior into the defect on the superior aspect of the autograft bone. View the accompanying video and see the related article at www.arthroscopytechniques.org. Courtesy of Laura Luick, M.D., Garrett Steinmetz, M.D., and Amgad Haleem, M.D., Ph.D.
Source: Arthroscopy - Journal of Arthroscopic and Related Surgery - April 30, 2020 Category: Surgery Source Type: research

Non-antibiotic prophylaxis in thyroid surgery. Experience of a single Institution and revision of literature.
CONCLUSIONS: Fever, neutrophilic leukocytosis and increased PCR cannot be assessed as predictive factors of infectious complication in thyroid surgery. The cutaneous antisepsis of the operative field with chlorhexidine gluconate, the improvement of the surgical technique, the protection of the cutaneous margins of incision, the use of new devices, the accurate hemostasis and the reduction of surgery time lead to a lack of SSIs and systemic infection complications in all patients undergoing thyroid surgery in NO-AP. KEY WORDS: Antibiotic prophylaxis, Surgical site infections, Thyroid surgery, Thyroidectomy. PMID: 32...
Source: Annali Italiani di Chirurgia - April 13, 2020 Category: Surgery Tags: Ann Ital Chir Source Type: research

A Comparative Efficacy Evaluation of Recombinant Topical Thrombin (RECOTHROM ®) With A Gelatin Sponge Carrier Versus Topical Oxidized Regenerated Cellulose (TABOTAMP®/SURGICEL®) In A Porcine Liver Bleeding Model.
Conclusions: In this model, rT plus gelatin sponge carrier (active) was a more effective hemostat than ORC (passive) in both heparinized and non-heparinized animals. PMID: 31955627 [PubMed - as supplied by publisher]
Source: Journal of Investigative Surgery - January 22, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Novel, infection-free, advanced hemostatic material: physical properties and preclinical efficacy.
Conclusions: TDM-623 has greater hemostatic capability than TDM-621 and is therefore promising as a new hemostatic agent. PMID: 31187670 [PubMed - as supplied by publisher]
Source: Minimally Invasive Therapy and Allied Technologies - June 14, 2019 Category: Surgery Tags: Minim Invasive Ther Allied Technol Source Type: research

Efficacy of New Polylactic Acid Nonwoven Fabric as a Hemostatic Agent in a Rat Liver Resection Model.
DISCUSSION: This new PLAF showed superior outcomes thanks to its unique characteristic of forming beaded nanofibers, and it has the potential to be an efficient hemostat in minimally invasive surgery in the human body. PMID: 30895890 [PubMed - as supplied by publisher]
Source: Surgical Innovation - March 20, 2019 Category: Surgery Authors: Wakabayashi T, Yagi H, Tajima K, Kuroda K, Shinoda M, Kitago M, Abe Y, Oshima G, Hirukawa K, Itano O, Kitagawa Y Tags: Surg Innov Source Type: research

Experimental Evaluation of a New Tissue Factor-Based Topical Hemostat (TT-173) for Treatment of Hepatic Bleeding.
CONCLUSIONS: TT-173 shows favorable pharmacodynamic properties for improving hemostasis in partial liver resection which support further investigation of the product in this surgical indication. PMID: 30380352 [PubMed - as supplied by publisher]
Source: Journal of Investigative Surgery - November 2, 2018 Category: Surgery Tags: J Invest Surg Source Type: research

Potent Hemostatic Efficacy of a Novel Recombinant Fibrin Sealant Patch (KTF-374) in Rabbit Bleeding Models.
CONCLUSIONS: These results suggest that KTF-374 possesses more potent hemostatic properties than FCCF for various patterns of bleeding. KTF-374 is a promising hemostat due to its potent efficacy and good visibility of the wound site through the patch. PMID: 29260920 [PubMed - as supplied by publisher]
Source: Journal of Investigative Surgery - December 22, 2017 Category: Surgery Tags: J Invest Surg Source Type: research

Vascular Trauma Revisited
Trauma with bleeding from named vessels has been treated since antiquity. Many of the techniques used in the modern era to control bleeding such as manual compression, cauterization, and proximal and distal ligatures were described before 1000 AD. Even the earliest version of a hemostat, Ambrose Pare ’s “Bec de Corbin”, was described in the 1500s.
Source: Journal of the American College of Surgeons - August 30, 2017 Category: Surgery Authors: David V. Feliciano Tags: Scudder Oration on Trauma Source Type: research

Superiority of Roeder's Knot for Fascial Mesh Fixation in a Cadaveric Model.
CONCLUSIONS: This study shows that Roeder's knot is superior to the regular sliding knot in securing the mesh to the abdominal wall. It can be tightened appropriately and leads to less variation when used properly. It has many other applications that stem from its ability to be advanced with different degrees of tightness based on body habitus and the operative requirements. PMID: 28689486 [PubMed - in process]
Source: Surgical Innovation - July 11, 2017 Category: Surgery Authors: Fanous M, Warren J, Cobb W Tags: Surg Innov Source Type: research