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Procedure: Transplants
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Total 5394 results found since Jan 2013.
Lung transplantation for coronavirus disease 2019 acute respiratory distress syndrome/fibrosis: silver lining of a global pandemic
Curr Opin Organ Transplant. 2023 Apr 7. doi: 10.1097/MOT.0000000000001068. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: The COVID-19 pandemic revolutionized the field of lung transplantation, as lung transplant is now an acceptable life-saving therapy for select patients with COVID-19-associated acute respiratory distress syndrome (ARDS), while prior to the pandemic, few transplants were performed for ARDS. This review article details the establishment of lung transplantation as a viable therapy for COVID-19-related respiratory failure, how to evaluate COVID-19 patients for lung transplant, and specific technical consi...
Source: Current Opinion in Organ Transplantation - April 11, 2023 Category: Transplant Surgery Authors: Emily J Cerier Ankit Bharat Source Type: research
Use of Tixagevimab and Cilgavimab (Evusheld) and Subsequent Outcomes of SARS-CoV-2 Infections in Lung Transplant Recipients
The protection of solid organ transplant recipients from infection has been challenging throughout the Coronavirus disease (COVID-19) pandemic. In 2022, tixagevimab and cilgavimab (Evusheld) was introduced as a means of providing passive antibodies and augmenting the vaccine immune response in immunocompromised patients. We aimed to assess the efficacy of Evusheld in reducing the incidence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in lung transplant recipients.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: A. Grillini, P. Stracener, D. Scarola, J. Lyons, D. Dilling Tags: (701) Source Type: research
Infection with Covid Variants of Concern in a Lung Transplant Population
The COVID pandemic has evolved as the SARS-2 Coronavirus (CoV-2) mutated into unique variants of concern (VOC). The clinical approach to COVID has evolved as new therapeutics have become available. Previous reports demonstrate differences in patient outcomes based on VOC, however outcomes in a lung transplant population have not been described.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: J.P. Rosenheck, V. Ramsammy, S. Kirkby, A. Ganapathi, N. Mokadam, M. Henn, S. Sarwar, C. Nichols, N. Marschalk, T. Fallah, P. Burcham, C. Sawyer, J. Mohr, S. Hoover, K. Nicholson, B. McLaughlin, R. Brown, S. Carter, K. Maas, J. Bennett, C. Shafner, M. Rei Tags: (693) Source Type: research
Heart Transplantation with Covid 19 Positive Donor Hearts
This study aims to analyze short and medium-term outcomes in recipients of hearts from COVID-19+ donors.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: S.B. Wolfe, R. Singh, D.C. Paneitz, R. Asija, S. Rabi, E. Michel, D. D'Alessandro, A. Ganapathi, A. Osho Tags: (416) Source Type: research
Effect of Seroconversion after SARS-CoV-2 Vaccination on the Severity of COVID-19 Disease in Heart Transplant Recipients
Heart transplant (HTX) recipients are prone to develop serious symptoms after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and their vaccination is often ineffective. In this high-volume single center study, we aimed to examine the seroconversion rates achieved with various types and doses of SARS-CoV-2 vaccines and assessed factors influencing vaccine immunogenicity and predictors of severe SARS-CoV-2 infection.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: S. Kugler, D. V ári, D. Veres, Á. Király, T. Teszák, N. Parázs, Z. Tarjányi, Z. Drobni, Z. Szakál-Tóth, G. Prinz, P. Miheller, B. Merkely, B. Sax Tags: (652) Source Type: research
Prolonged V.v.-Ecmo for Covid-19 Ards with Lung Recovery
We present a patient with lung recovery after an eight-month ECMO course for COVID-19.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: A. Beckett, L. Michalik, A. Tatooles Tags: (591) Source Type: research
Biopsy-Proven Fulminant Myocarditis Requiring Mechanical Circulatory Support Following Third Dose of COVID-19 MRNA Vaccination
Myocarditis has been recognized as a rare complication of coronavirus disease 2019 (COVID-19) messenger RNA (mRNA) vaccinations. The frequency of the event was reported 2-3 cases per million vaccinations. Clinical courses remain variable, ranging from asymptomatic to severe heart failure requires mechanical circulatory supports (MCS). Here we report a case of fulminant myocarditis requiring MCS following COVID-19 mRNA vaccination.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: T. Hamaya, T. Sato, Y. Kobayashi, Y. Mori, K. Kamiya, N. Otsuka, T. Nagai, T. Anzai Tags: (821) Source Type: research
Prevalence and Determinants of Cellular Immunity Against Sars-Cov-2 in Heart Transplant Recipients: A Cross-Sectional Study
Serology studies provide limited information on immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This cross-sectional study aimed to assess prevalence and determinants of anti-SARS-CoV-2 cellular immunity in a cohort of heart transplant (HT) recipients.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: H. Flament, M. Ben Ahmed, C. Kfoury, V. Ferr é, M. Para, V. Da Silva Melo, C. Charpentier, N. Houhou-Fidouh, E. Vicaut, D. Descamps, R. Dorent Tags: (61) Source Type: research
The Impact Of Years Since Transplant On The Clinical Course After SARS-CoV-2 Infection In Heart Transplant Recipients
The risk of Severe Acute Respiratory Syndrome - Coronavirus-2 (SARS-CoV-2) infection and mortality is higher in heart transplant (HT) recipients compared to immunocompetent individuals. The impact of years since transplant on clinical course risk is unknown. We evaluated the differences in clinical phenotypes and outcomes according to years since transplant in HT recipients with active SARS-CoV-2 infection.
Source: Journal of Cardiac Failure - April 1, 2023 Category: Cardiology Authors: Carlos Nicol ás Pérez-García, Safia Aslam, Victoria Cooper, Barbara Parlon, Tomcy Baby, Eimear Dempsey, Katie Murphy, Emer Joyce Tags: 186 Source Type: research
Impact of Donor Specific Antibodies in Cardiac Transplant Recipients after Acute Covid-19
Donor specific antibodies (DSA) are known to be associated with increased mortality following heart transplant (HT). Despite the high overall burden of disease from novel coronavirus (COVID-19) among HT recipients, little is known about the subsequent development of de novo or increased DSA (diDSA) in COVID-19 survivors.
Source: The Journal of Heart and Lung Transplantation - April 1, 2023 Category: Transplant Surgery Authors: J.A. Martissa, M.J. Gregoski, B. Houston, A. Kilic, A. Celia, S. Shore, A. Tamas, V. Maharaj, A.C. Agdamag, E. Vorovich, L.A. Farina, H. Vidula, R. Sampath, S. Hsiao, K. Alexander, A. Jamil, E. Birati, S. Chaudhry, A. Patel, R.J. Tedford, M.V. Genuardi Tags: (60) Source Type: research
Relationship Between Covid-19 And Donor Specific Antibodies In Orthotopic Heart Transplant Recipients
De novo donor specific antibodies (DSAs) are associated with increased risk of antibody-mediated rejection (AMR) and worse prognosis in patients after orthotopic heart transplant (OHT). Viral infections have the potential to induce or reactivate the production of DSAs, yet the development of DSAs after infection by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has not been reported. In this observational study, we describe DSA titers after Coronavirus Disease 2019 (COVID-19) infection and relationship with AMR and graft dysfunction in a large OHT cohort at a tertiary academic medical center.
Source: Journal of Cardiac Failure - April 1, 2023 Category: Cardiology Authors: Bin Q Yang, Justin Vader, David Lambert, Richard Petrella, Joel Schilling, Amanda Verma Tags: 177 Source Type: research
Outcome of SARS-CoV2 infection in hematopoietic stem cell transplant recipients for autoimmune diseases
J Autoimmun. 2023 Mar 2;136:103024. doi: 10.1016/j.jaut.2023.103024. Online ahead of print.ABSTRACTHematopoietic stem cell transplant (HSCT) recipients may be at high risk of mortality from coronavirus disease 2019 (COVID-19). However, specific data on COVID-19 after treatment with HSCT in patients affected by autoimmune diseases (ADs) are still lacking. In this multicenter observational study of the European Society for Blood and Marrow Transplantation (EBMT), clinical data on COVID-19 in 11 patients affected by severe ADs treated with HSCT (n = 3 allogeneic transplant; n = 8 autologous transplant) are reported. All patie...
Source: Journal of Autoimmunity - March 31, 2023 Category: Allergy & Immunology Authors: Raffaella Greco John A Snowden Nina Simone Knelange Gloria Tridello Carlotta Cacciatore Alienor Xhaard Fabio Ciceri Matthew Collin Christelle Ferra Ann De Becker Manuela Badoglio Dina Averbuch Tobias Alexander Per Ljungman Rafael De la Camara European Soc Source Type: research
