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Total 5394 results found since Jan 2013.

Interaction of COVID-19 With Common Cardiovascular Disorders
Circ Res. 2023 May 12;132(10):1259-1271. doi: 10.1161/CIRCRESAHA.122.321952. Epub 2023 May 11.ABSTRACTThe onset and widespread dissemination of the severe acute respiratory syndrome coronavirus-2 in late 2019 impacted the world in a way not seen since the 1918 H1N1 pandemic, colloquially known as the Spanish Flu. Much like the Spanish Flu, which was observed to disproportionately impact young adults, it became clear in the early days of the coronavirus disease 2019 (COVID-19) pandemic that certain groups appeared to be at higher risk for severe illness once infected. One such group that immediately came to the forefront an...
Source: Circulation Research - May 11, 2023 Category: Cardiology Authors: Peter K Boulos Scott V Freeman Timothy D Henry Ehtisham Mahmud John C Messenger Source Type: research

Lessons from SENCOVAC: A prospective study evaluating the response to SARS-CoV-2 vaccination in the CKD spectrum
Nefrologia (Engl Ed). 2023 May 5:S2013-2514(23)00074-3. doi: 10.1016/j.nefroe.2023.04.005. Online ahead of print.ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has negatively impacted on patients of the whole CKD spectrum, causing high rates of morbi-mortality. SARS-CoV-2 vaccines opened a new era, but patients with CKD (including kidney transplant, hemodialysis and peritoneal dialysis) were systematically excluded from pivotal clinical trials. The Spanish Society of Nephrology promoted the multicentric national SENCOVAC study aimed at assessing immunological responses after vaccination in patients wi...
Source: Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - May 7, 2023 Category: Urology & Nephrology Authors: Borja Quiroga Mar ía José Soler Alberto Ortiz Patricia de Sequera SENCOVAC collaborative network Source Type: research

Risk factors and characteristics influencing humoral response to COVID-19 vaccination in patients after allogeneic stem cell transplantation
DiscussionWe showed in our bicentric allo-SCT patient cohort, that a humoral response could be achieve after the regular approved schedule, especially for those patients who underwent immune reconstitution and were free from immunosuppressive drugs. In over 50% of the initial non-responders after 2-dose vaccination, a seroconversion can be achieved by boostering with a third dose.
Source: Frontiers in Immunology - May 3, 2023 Category: Allergy & Immunology Source Type: research

The relationship between gut microbiota and COVID-19 progression: new insights into immunopathogenesis and treatment
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed a global health crisis. Increasing evidence underlines the key role of competent immune responses in resisting SARS-CoV-2 infection and manifests the disastrous consequence of host immune dysregulation. Elucidating the mechanisms responsible for deregulated host immunity in COVID-19 may provide a theoretical basis for further research on new treatment modalities. Gut microbiota comprises trillions of microorganisms colonizing the human gastrointestinal tract and has a vital role in immune homeos...
Source: Frontiers in Immunology - May 2, 2023 Category: Allergy & Immunology Source Type: research

Assessing the impact of COVID-19 on the performance of organ transplant services using data envelopment analysis
Abstract Organ transplant is one of the best options for many medical conditions, and in many cases, it may be the only treatment option. Recent evidence suggests, however, that the COVID-19 pandemic might have detrimentally affected the provision of this type of healthcare services. The main purpose of this article is to use Data Envelopment Analysis and the Malmquist Index to assess the impact that the pandemic caused by the novel coronavirus SARS-CoV-2 had on the provision of solid organ transplant services. To this purpose, we use three complementary models, each focusing on specific aspects of the organ donation and...
Source: Health Care Management Science - April 26, 2023 Category: Health Management Source Type: research

Analysis of Antibody Responses After COVID-19 Vaccination in Liver Transplant Recipients: A Single-Center Study
CONCLUSION: A higher TAC level before vaccination resulted in less effective vaccination in LT patients. Booster vaccinations are required, especially for patients in the early stage after LT who have compromised immune function.PMID:37096307 | PMC:PMC10125795 | DOI:10.3346/jkms.2023.38.e121
Source: J Korean Med Sci - April 25, 2023 Category: General Medicine Authors: Young Ju Oh Jongman Kim Eun-Suk Kang Jinsoo Rhu Gyu-Seong Choi Jae-Won Joh Source Type: research