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Total 7156 results found since Jan 2013.

Acute motor-sensory axonal polyneuropathy variant of Guillain-Barr é syndrome with a thalamic lesion and COVID-19: a case report and discussion on mechanism
ConclusionThe AMSAN variant of GBS secondary to COVID-19 infection is severe and can cause extensive damage to the peripheral nerves system. The deterioration of symptoms in the patient after early immunotherapy may indicate treatment-related fluctuation (TRF) and could be attributed to immune rebound. Moreover, an excessive immune response post-COVID-19 infection may trigger concurrent damage to the central nervous system, indicating secondary harm to brain small blood vessels and nerve units. For suspected cases of GBS complicated by COVID-19, it is essential to conduct early brain MRI examinations in addition to routine...
Source: Frontiers in Neurology - September 14, 2023 Category: Neurology Source Type: research

Clinical and epidemiological factors causing longer SARS-CoV 2 viral shedding: the results from the CoviCamp cohort
DiscussionOur analysis showed that CKD is a factor related to longer time-to-negative swab, probably because of immunosuppression related to this condition.
Source: Infection - September 13, 2023 Category: Infectious Diseases Source Type: research

SARS-CoV-2 infection induces a long-lived pro-inflammatory transcriptional profile
ConclusionsSARS-CoV-2 infection causes a prolonged increase in the pro-inflammatory transcriptional status that could predispose post-acute patients to the development of long-term health consequences, including autoimmune disease, reactivation of other viruses and disruption of the host immune system-microbiome ecosystem.
Source: Genome Medicine - September 12, 2023 Category: Genetics & Stem Cells Source Type: research

Metformin and Covid-19: a systematic review of systematic reviews with meta-analysis
Conclusions More in-depth studies on the use of metformin, compared to other molecules, may be required to understand the real protective potential of the drug against negative outcomes caused by COVID-19 infection in DM2 patients.PMID:37695186 | DOI:10.23750/abm.v94iS3.14405
Source: Acta Bio-Medica : Atenei Parmensis - September 11, 2023 Category: General Medicine Authors: Fabio Petrelli Iolanda Grappasonni Cuc Thi Thu Nguyen Marina Tesauro Paola Pantanetti Sonila Xhafa Giovanni Cangelosi Source Type: research

Determinants of health ‐related quality of life in children and adolescents living with type 1 diabetes mellitus during the COVID‐19 pandemic
AbstractAimTo identify the determinants of self-reported health-related quality of life in children and adolescents with type 1 diabetes mellitus during the coronavirus pandemic.DesignA cross-sectional study.MethodsThe study sample included 182 children and adolescents who had been diagnosed with type 1 diabetes mellitus at least 3  months prior. Data collection instruments included sociodemographic and glycaemic control protocol adherence questionnaires, documentation sheet for recording clinical data, and Serbian versions of the EuroQol-5D-Y and KidScreen27 questionnaires, which were used to assess health-related quali...
Source: Nursing Open - September 9, 2023 Category: Nursing Authors: Mirjana Smudja, Tatjana Milenkovic, Ivana Minakovic, Vera Zdravkovic, Sandra Mitic, Dragana Milutinovic Tags: EMPIRICAL RESEARCH QUANTITATIVE Source Type: research

COVID-19 in patients with rheumatological diseases in the Eastern Province of Saudi Arabia
J Med Life. 2023 Jun;16(6):873-882. doi: 10.25122/jml-2023-0037.ABSTRACTThe severity of the 2019 coronavirus disease (COVID-19) and its effects remain unpredictable. Certain factors, such as obesity, hypertension, and type 2 diabetes mellitus, may increase the severity of the disease. Rheumatology experts suggest that patients with active autoimmune conditions and controlled autoimmune diseases on immunosuppressive therapy may be at higher risk of developing severe COVID-19. In this retrospective observational study, we aimed to examine the patterns of COVID-19 in patients with underlying rheumatological diseases and their...
Source: Journal of Medicine and Life - September 7, 2023 Category: General Medicine Authors: Safi Alqatari Ameera Nemer Manal Hasan Raed Bukhari Reem Al Argan Dania Al Khafaji Abrar Alwaheed Alaa Alzaki Marwan Al-Wazza Sara Al Warthan Abir Al Saeed Feda Albeladi Hashim Almeer Reem AlSulaiman Ahmed Abu Quren Source Type: research