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Total 7156 results found since Jan 2013.
COVID-19 in patients with rheumatological diseases in the Eastern Province of Saudi Arabia
J Med Life. 2023 Jun;16(6):873-882. doi: 10.25122/jml-2023-0037.ABSTRACTThe severity of the 2019 coronavirus disease (COVID-19) and its effects remain unpredictable. Certain factors, such as obesity, hypertension, and type 2 diabetes mellitus, may increase the severity of the disease. Rheumatology experts suggest that patients with active autoimmune conditions and controlled autoimmune diseases on immunosuppressive therapy may be at higher risk of developing severe COVID-19. In this retrospective observational study, we aimed to examine the patterns of COVID-19 in patients with underlying rheumatological diseases and their...
Source: Journal of Medicine and Life - September 7, 2023 Category: General Medicine Authors: Safi Alqatari Ameera Nemer Manal Hasan Raed Bukhari Reem Al Argan Dania Al Khafaji Abrar Alwaheed Alaa Alzaki Marwan Al-Wazza Sara Al Warthan Abir Al Saeed Feda Albeladi Hashim Almeer Reem AlSulaiman Ahmed Abu Quren Source Type: research
Metformin for the prevention of diabetes among people with HIV and either impaired fasting glucose or impaired glucose tolerance (prediabetes) in Tanzania: a Phase II randomised placebo-controlled trial
Conclusions/interpretationBlood glucose decreased over time in both the metformin and placebo arms during the trial but did not differ significantly between the arms at 12 months of follow up. Metformin therapy was found to be safe for use in individuals with HIV and prediabetes. A larger trial with longer follow up is needed to establish if metformin can be safely used for the prevention of diabetes in people who have HIV.Trial registrationThe trial is registered on the International Standard Randomised Controlled Trial Number (ISRCTN) registry (www.isrctn.com/), registration number: ISCRTN76157257.FundingThis research wa...
Source: Diabetologia - September 3, 2023 Category: Endocrinology Source Type: research
15-lipoxygenase and cyclooxygenase expression profile and their related modulators in COVID-19 infection
After the outbreak of COVID-19 infection, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection led to disability, hospitalization and death of a large number of people around the world [1]. This virus belongs to the Coronaviridae family that is a single-stranded RNA virus (positive-sense) and causes the spectrum of clinical manifestations in infected patients ranging from fever, cough, chest and body pain, myalgia, dyspnea, headache to mortality [2]. Adult male and elderly are more vulnerable to the disease, and cardiac, diabetic, and metabolic diseases are considered as main risk factors for this infection [3].
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - September 3, 2023 Category: Biomedical Science Authors: Sara Kianfar, Vahid Salimi, Alireza Jahangirifard, Seyed Bashir Mirtajani, Mohammad Amin Vaezi, Jila Yavarian, Talat Mokhtari-Azad, Masoumeh Tavakoli-Yaraki Tags: Original research article Source Type: research
Metformin for the prevention of diabetes among people with HIV and either impaired fasting glucose or impaired glucose tolerance (prediabetes) in Tanzania: a Phase II randomised placebo-controlled trial
Conclusions/interpretationBlood glucose decreased over time in both the metformin and placebo arms during the trial but did not differ significantly between the arms at 12 months of follow up. Metformin therapy was found to be safe for use in individuals with HIV and prediabetes. A larger trial with longer follow up is needed to establish if metformin can be safely used for the prevention of diabetes in people who have HIV.Trial registrationThe trial is registered on the International Standard Randomised Controlled Trial Number (ISRCTN) registry (www.isrctn.com/), registration number: ISCRTN76157257.FundingThis research wa...
Source: Diabetologia - September 1, 2023 Category: Endocrinology Source Type: research
Comparative assessment of SARS CoV2-associated mortalities in 3 COVID waves and related risk factors: The South Kashmir's experience
CONCLUSION: We identify the peaked mortalities in the second encounter which was predicted by age, comorbidities such as hypertension, and diabetes.PMID:37649761 | PMC:PMC10465047 | DOI:10.4103/jfmpc.jfmpc_2318_22
Source: Primary Care - August 31, 2023 Category: Primary Care Authors: Shujat Gul Asifa Ali Nawaz Ahmad Sheikh Irfan Gul Tariq Sultan Sheikh Priyadarshi Prajjwal Source Type: research
Could ischemia-modified albumin levels predict the severity of disease in SARS-CoV-2 infection?
Conclusions: We analyzed a sample of patients with COVID-19 infection and found that IMA predicted severe COVID-19 disease. Disease severity grouping was based on patients ' clinical and radiological features. IMA level measured when SARS-CoV-2 infection is diagnosed may be a useful marker in predicting likely disease severity or intensive care need.
Source: The Journal of Infection in Developing Countries - August 30, 2023 Category: Infectious Diseases Authors: Mustafa Tanr ıverdi, Nevhiz Gündoğdu, Necla Benlier, Mustafa Yıldırım, Hale Çeliktürk, Hanifi Ayhan Özkur, Pınar Günel Karadeniz, Gülşen Özkan Tanrıverdi, Hülya Çiçek Source Type: research
