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Total 29421 results found since Jan 2013.

Spermidine - an old molecule with a new age-defying immune function
Trends Cell Biol. 2023 Sep 16:S0962-8924(23)00166-6. doi: 10.1016/j.tcb.2023.08.002. Online ahead of print.ABSTRACTPolyamines - putrescine, spermidine, and spermine - are widely distributed aliphatic compounds known to regulate important biological processes in prokaryotic and eukaryotic cells. Therefore, spermidine insufficiency is associated with various physio-pathological processes, such as aging and cancers. Recent advances in immuno-metabolism and immunotherapy shed new light on the role of spermidine in immune cell regulation and anticancer responses. Here, we review novel works demonstrating that spermidine is prod...
Source: Trends in Cell Biology - September 18, 2023 Category: Cytology Authors: Kenji Chamoto Baihao Zhang Masaki Tajima Tasuku Honjo Sidonia Fagarasan Source Type: research

Trends in consultations and prescribing for rheumatic and musculoskeletal diseases: an electronic primary care records study
CONCLUSION: Pandemic-associated restrictions led to fewer primary care consultations and relative increases in analgesic prescribing, including strong opioids, for RMDs in the UK. Policymakers must consider the impact of these changes in future healthcare resource planning.PMID:37722859 | DOI:10.3399/BJGP.2022.0648
Source: The British Journal of General Practice - September 18, 2023 Category: Primary Care Authors: Victoria K Welsh Kayleigh J Mason James Bailey Ram Bajpai Kelvin P Jordan Christian D Mallen Claire Burton Source Type: research

Unlocking the secrets of soil microbes: How decades-long contamination and heavy metals accumulation from sewage water and industrial effluents shape soil biological health
Chemosphere. 2023 Sep 16:140193. doi: 10.1016/j.chemosphere.2023.140193. Online ahead of print.ABSTRACTHeavy metals contamination is posing severe threat to the soil health and environmental sustainability. Application of industrial and sewage waste as irrigation and growing urbanization and agricultural industry is the main reason for heavy metals pollution. Therefore, the present study was planned to assess the influence of different irrigation sources such as industrial effluents, sewage wastewater, tube well water, and canal water on the soil physio-chemical, soil biological, and enzymatic characteristics. Results show...
Source: Chemosphere - September 18, 2023 Category: Chemistry Authors: Idrees Haider Muhammad Arif Ali Muhammad Sanaullah Niaz Ahmed Sajjad Hussain Muhammad Taimoor Shakeel Syed Atif Hasan Naqvi Javeed Shabbir Dar Mahmoud Moustafa Mohammed O Alshaharni Source Type: research

Trends in consultations and prescribing for rheumatic and musculoskeletal diseases: an electronic primary care records study
CONCLUSION: Pandemic-associated restrictions led to fewer primary care consultations and relative increases in analgesic prescribing, including strong opioids, for RMDs in the UK. Policymakers must consider the impact of these changes in future healthcare resource planning.PMID:37722859 | DOI:10.3399/BJGP.2022.0648
Source: The British Journal of General Practice - September 18, 2023 Category: Primary Care Authors: Victoria K Welsh Kayleigh J Mason James Bailey Ram Bajpai Kelvin P Jordan Christian D Mallen Claire Burton Source Type: research

Spermidine - an old molecule with a new age-defying immune function
Trends Cell Biol. 2023 Sep 16:S0962-8924(23)00166-6. doi: 10.1016/j.tcb.2023.08.002. Online ahead of print.ABSTRACTPolyamines - putrescine, spermidine, and spermine - are widely distributed aliphatic compounds known to regulate important biological processes in prokaryotic and eukaryotic cells. Therefore, spermidine insufficiency is associated with various physio-pathological processes, such as aging and cancers. Recent advances in immuno-metabolism and immunotherapy shed new light on the role of spermidine in immune cell regulation and anticancer responses. Here, we review novel works demonstrating that spermidine is prod...
Source: Trends in Cell Biology - September 18, 2023 Category: Cytology Authors: Kenji Chamoto Baihao Zhang Masaki Tajima Tasuku Honjo Sidonia Fagarasan Source Type: research

Unlocking the secrets of soil microbes: How decades-long contamination and heavy metals accumulation from sewage water and industrial effluents shape soil biological health
Chemosphere. 2023 Sep 16:140193. doi: 10.1016/j.chemosphere.2023.140193. Online ahead of print.ABSTRACTHeavy metals contamination is posing severe threat to the soil health and environmental sustainability. Application of industrial and sewage waste as irrigation and growing urbanization and agricultural industry is the main reason for heavy metals pollution. Therefore, the present study was planned to assess the influence of different irrigation sources such as industrial effluents, sewage wastewater, tube well water, and canal water on the soil physio-chemical, soil biological, and enzymatic characteristics. Results show...
Source: Chemosphere - September 18, 2023 Category: Chemistry Authors: Idrees Haider Muhammad Arif Ali Muhammad Sanaullah Niaz Ahmed Sajjad Hussain Muhammad Taimoor Shakeel Syed Atif Hasan Naqvi Javeed Shabbir Dar Mahmoud Moustafa Mohammed O Alshaharni Source Type: research

Enthesitis in Spondyloarthritis Including Psoriatic Arthritis-To Inject or Not To Inject?: A Narrative Review
Clin Ther. 2023 Sep 14:S0149-2918(23)00303-X. doi: 10.1016/j.clinthera.2023.08.002. Online ahead of print.ABSTRACTPURPOSE: Enthesitis is a key manifestation of psoriatic arthritis (PsA) and spondyloarthritis (SpA) and is considered to be the tissue where the disease initiates. Enthesitis leads to pain and substantial limitations in patients with PsA. Treatment is key in achieving remission or minimal disease activity. Whether it is safe to apply injections to entheseal tissue is unknown. This narrative review aimed to summarize the literature on the efficacy and tolerability of entheseal corticosteroid (CS) injections.METH...
Source: Clinical Therapeutics - September 16, 2023 Category: Drugs & Pharmacology Authors: Ozun Bayindir Tsechelidis Ricardo Sabido-Sauri Sibel Zehra Aydin Source Type: research

Reclassification of < em > Streptomyces griseostramineus < /em > as a synonym of < em > Streptomyces griseomycini < /em > based on a polyphasic taxonomic approach
Int J Syst Evol Microbiol. 2023 Sep;73(9). doi: 10.1099/ijsem.0.006021.ABSTRACTIn the present work, the taxonomic relationship between Streptomyces griseomycini and Streptomyces griseostramineus was reevaluated by a comprehensive comparison of phenotypic, chemotaxonomic and genomic characteristics, as well as phylogeny. Phylogenetic analysis based on 16S rRNA gene sequences and whole-genome sequences indicated that Streptomyces griseostramineus JCM 4385T was clustered together with Streptomyces griseomycini JCM 4382T, suggesting they were closely related to each other. However, the average nucleotide identity (ANI) and dig...
Source: International Journal of Systematic and Evolutionary Microbiology - September 15, 2023 Category: Microbiology Authors: Yinfeng Wang PeiLan Long Li Fu Yan Xiao Nengqiang Wang Jian Gao Source Type: research