Filtered By:
Infectious Disease: Coronavirus
This page shows you your search results in order of date. This is page number 12.
Order by Relevance | Date
Total 72349 results found since Jan 2013.
The old and the new: The EG.5 ('Eris') sub-variant of Coronavirus
Eur J Intern Med. 2023 Sep 8:S0953-6205(23)00323-0. doi: 10.1016/j.ejim.2023.09.003. Online ahead of print.NO ABSTRACTPMID:37690919 | DOI:10.1016/j.ejim.2023.09.003
Source: European Journal of Internal Medicine - September 10, 2023 Category: Internal Medicine Authors: Martina Zappa Paolo Verdecchia Andrea Andolina Fabio Angeli Source Type: research
HLA alleles: important pieces to the COVID-19 puzzle
Trends Immunol. 2023 Sep 9:S1471-4906(23)00179-5. doi: 10.1016/j.it.2023.08.011. Online ahead of print.ABSTRACTResearch on human leukocyte antigen (HLA) molecules in coronavirus disease 2019 (COVID-19) raised high expectations but has yielded limited results. Augusto et al.'s recent study in Nature unveils a strong association of HLA-B*15:01 with asymptomatic COVID-19, representing an important contribution to genetics in COVID-19.PMID:37690961 | DOI:10.1016/j.it.2023.08.011
Source: Trends in Immunology - September 10, 2023 Category: Allergy & Immunology Authors: Patricia Castro-Santos Ángel Carracedo Roberto D íaz-Peña Source Type: research
The old and the new: The EG.5 ('Eris') sub-variant of Coronavirus
Eur J Intern Med. 2023 Sep 8:S0953-6205(23)00323-0. doi: 10.1016/j.ejim.2023.09.003. Online ahead of print.NO ABSTRACTPMID:37690919 | DOI:10.1016/j.ejim.2023.09.003
Source: European Journal of Internal Medicine - September 10, 2023 Category: Internal Medicine Authors: Martina Zappa Paolo Verdecchia Andrea Andolina Fabio Angeli Source Type: research
Analytical tool for COVID-19 using an SIR model equivalent to the chain reaction equation of infection
Biosystems. 2023 Sep 8:105029. doi: 10.1016/j.biosystems.2023.105029. Online ahead of print.ABSTRACTInsights from data analysis of existing cases are important to prevent future outbreaks of coronavirus disease 2019 (COVID-19). Although mathematical models are expected to be useful for this purpose, the adequacy of reproducibility of these models is difficult to confirm because they are based on hypotheses. For example, using the time variation of the parameter of the basic reproduction number for the time variation of complex data on the number of infected persons is a change of expression and does not capture the substan...
Source: Biosystems - September 10, 2023 Category: Biotechnology Authors: Koichiro Maki Source Type: research
The old and the new: The EG.5 ('Eris') sub-variant of Coronavirus
Eur J Intern Med. 2023 Sep 8:S0953-6205(23)00323-0. doi: 10.1016/j.ejim.2023.09.003. Online ahead of print.NO ABSTRACTPMID:37690919 | DOI:10.1016/j.ejim.2023.09.003
Source: European Journal of Internal Medicine - September 10, 2023 Category: Internal Medicine Authors: Martina Zappa Paolo Verdecchia Andrea Andolina Fabio Angeli Source Type: research
HLA alleles: important pieces to the COVID-19 puzzle
Trends Immunol. 2023 Sep 9:S1471-4906(23)00179-5. doi: 10.1016/j.it.2023.08.011. Online ahead of print.ABSTRACTResearch on human leukocyte antigen (HLA) molecules in coronavirus disease 2019 (COVID-19) raised high expectations but has yielded limited results. Augusto et al.'s recent study in Nature unveils a strong association of HLA-B*15:01 with asymptomatic COVID-19, representing an important contribution to genetics in COVID-19.PMID:37690961 | DOI:10.1016/j.it.2023.08.011
Source: Trends in Immunology - September 10, 2023 Category: Allergy & Immunology Authors: Patricia Castro-Santos Ángel Carracedo Roberto D íaz-Peña Source Type: research
Natural PAK1 inhibitors: potent anti-inflammatory effectors for prevention of pulmonary fibrosis in COVID-19 therapy
Nat Prod Res. 2023 Sep 10:1-13. doi: 10.1080/14786419.2023.2254454. Online ahead of print.ABSTRACTOne of the main efforts of scientists to study drug development is the discovery of novel antiviral agents that could be beneficial in the struggle against viruses that cause diseases in humans. Natural products are complex metabolites that are designed and synthesised by different sources in an attempt to optimise nature. Recently, natural products are still a source of biologically active molecules, facilitating drug discovery. A p21-activating kinase PAK1 is a key regulator of cytoskeletal actin assembly, phenotypic signall...
Source: Natural Product Research - September 10, 2023 Category: Biochemistry Authors: Idris Arslan Source Type: research
HLA alleles: important pieces to the COVID-19 puzzle
Trends Immunol. 2023 Sep 9:S1471-4906(23)00179-5. doi: 10.1016/j.it.2023.08.011. Online ahead of print.ABSTRACTResearch on human leukocyte antigen (HLA) molecules in coronavirus disease 2019 (COVID-19) raised high expectations but has yielded limited results. Augusto et al.'s recent study in Nature unveils a strong association of HLA-B*15:01 with asymptomatic COVID-19, representing an important contribution to genetics in COVID-19.PMID:37690961 | DOI:10.1016/j.it.2023.08.011
Source: Trends in Immunology - September 10, 2023 Category: Allergy & Immunology Authors: Patricia Castro-Santos Ángel Carracedo Roberto D íaz-Peña Source Type: research
Quantitative analysis of respiratory viruses based on lab-on-a-chip platform
Anal Bioanal Chem. 2023 Sep 8. doi: 10.1007/s00216-023-04935-w. Online ahead of print.ABSTRACTThe quantitative analysis of respiratory viruses is of great importance for rapid diagnosis, precision medicine, and prognosis. Several current quantitative analysis systems have been proposed and commercialized. Although they have been proven in trials, quantitative analyzes based on real samples are still complex, time-consuming, and expensive. Therefore, they are not able to directly quantify real samples. In this work, we presented a lab-on-a-chip platform combined with an automated control system to achieve quantitative analy...
Source: Analytical and Bioanalytical Chemistry - September 8, 2023 Category: Chemistry Authors: Ning Zhang Chao Yue Xiaobo Zhan Zhi Cheng Chao Li Yaohua Du Feng Tian Source Type: research
Percutaneous cholecystostomy in the management of acute cholecystitis-comparative analysis of before and after the COVID 19 pandemic
CONCLUSION: PC is an effective and safe treatment method that reduced the operating room and intensive care burden during the exacerbation of the COVID 19 pandemic. Therefore, it seems like a logical option to expand the PC indications at times when the number of COVID 19 patients increases.PMID:37681720 | DOI:10.14744/tjtes.2023.22901
Source: Turkish Journal of Trauma and Emergency Surgery : TJTES - September 8, 2023 Category: Emergency Medicine Authors: Fatih K ılınç Çağlayan Çakır Ömer Yıldız Alpen Yahya G ümüşoğlu Abd ülcelil Gezmiş Fidan Ayg ün Source Type: research
The significance of IFITM3 polymorphism in COVID-19 asymptomatic and ICU admission Kurdish patients
CONCLUSION: This study demonstrated that the rs12252 AA genotype is probably associated with asymptomatic COVID-19. In addition, the patients having haplotypes of minor alleles rs12252, rs34481144, and rs7478728 may be associated to COVID-19 ICU admission.PMID:37683443 | DOI:10.1016/j.cyto.2023.156349
Source: Cytokine - September 8, 2023 Category: Molecular Biology Authors: Peshnyar M A Rashid Gaza F Salih Source Type: research
Person-centred critical care for a person with learning disability and COVID-19: case study of positive risk taking
Br J Nurs. 2023 Sep 7;32(16):776-784. doi: 10.12968/bjon.2023.32.16.776.ABSTRACTPeople with learning disabilities are known to experience a wide range of health inequalities and have a lower life expectancy than the general population. During the COVID-19 pandemic this extended to higher mortality rates following infection with the novel coronavirus. This case study presents an example of a positive outcome for Jade, a 21-year-old woman with learning disabilities and autism who required a long period in intensive care following COVID-19 infection. It demonstrates the impact of effective multidisciplinary collaboration invo...
Source: British Journal of Nursing - September 8, 2023 Category: Nursing Authors: Penny Clarke Rachel Brannan Scott Taylor Juliet MacArthur Source Type: research
Broad-Spectrum Antiviral Effect of Cannabidiol Against Enveloped and Nonenveloped Viruses
Conclusions: It was demonstrated that CBD inhibits structurally dissimilar viruses, suggesting that this phytochemical has broad-spectrum antiviral effect, representing a valuable alternative in emergency situations during viral outbreaks, like the one caused by severe acute respiratory syndrome coronavirus 2 in 2020.PMID:37682578 | DOI:10.1089/can.2023.0103
Source: Cell Research - September 8, 2023 Category: Cytology Authors: Agostina B Marquez Josefina Vicente Eliana Castro Daiana Vota Mar ía S Rodríguez-Varela Priscila A Lanza Castronuovo Giselle M Fuentes Alejandro R Parise Leonardo Romorini Diego E Alvarez Carlos A Bueno Cristina L Ramirez Agustina Alaimo Cybele C Garc Source Type: research
Discovery of new non-covalent and covalent inhibitors targeting SARS-CoV-2 papain-like protease and main protease
In this report, we identified [1,2]selenazolo[5,4-c]pyridin-3(2H)-one and benzo[d]isothiazol-3(2H)-one as attractive scaffolds of PLpro and Mpro inhibitors. The representative compounds 6c and 7e exhibited excellent PLpro inhibition with percent inhibition of 42.9% and 44.9% at 50 nM, respectively. The preliminary enzyme kinetics experiment and fluorescent labelling experiment results determined that 6c was identified as a covalent PLpro inhibitor, while 7e was a non-covalent inhibitor. Molecular docking and dynamics simulations revealed that 6c and 7e bound to Zn-finger domain of PLpro. Compounds 6c and 7e were also ident...
Source: Bioorganic Chemistry - September 8, 2023 Category: Chemistry Authors: Wandong Liu Juan Wang Suyun Wang Kairui Yue Yu Hu Xiaochun Liu Lihao Wang Shengbiao Wan Ximing Xu Source Type: research
