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Infectious Disease: Coronavirus

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Total 72349 results found since Jan 2013.

Identifying luteolin as a potential drug for treating lung adenocarcinoma with COVID-19 affection based on integration analysis of pharmacology and transcriptome
CONCLUSION: HSP90AA1 was a target gene for further designing effective drugs for LUAD patients. Luteolin was a potential drug for treating patients with both LUAD and COVID-19.PMID:37694790 | DOI:10.2174/0929867331666230908090326
Source: Current Medicinal Chemistry - September 11, 2023 Category: Chemistry Authors: Ping Peng Na Li Ni Zhang Xiangning Fu Shu Peng Yujie Zhao Bo Ai Source Type: research

Recombination in sarbecovirus lineage and mutations/insertions in spike protein are linked to the emergence and adaptation of SARS-CoV-2
Bioinformation. 2022 Oct 31;18(10):951-961. doi: 10.6026/97320630018951. eCollection 2022.ABSTRACTThe outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan city, China in December 2019 and thereafter its spillover across the world has created a global pandemic and public health crisis. Right after, there has been intense interest in understanding how the SARS-CoV-2 originated and evolved. This paper also aims to shed light on the origin and evolution of SARS-CoV- 2. A consensus result based on whole genome phylogeny, gene tree analysis, and genetic similarity study revealed that SARS-CoV-2 evolv...
Source: Bioinformation - September 11, 2023 Category: Bioinformatics Authors: Anup Som Amresh Kumar Sharma Priyanka Kumari Source Type: research

The impact of the COVID-19 pandemic on erectile function in Chinese CP/CPPS patients
This study aimed to investigate the impact of the coronavirus disease 2019 (COVID-19) pandemic on erectile function in Chinese patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). A retrospective study was conducted on 657 CP/CPPS patients who visited The Third Xiangya Hospital of Central South University (Changsha, China) from November 2018 to November 2022. Patients were divided into two groups based on the timeline before and after the COVID-19 outbreak in China. The severity of CP/CPPS, penile erection status, anxiety, and depression was evaluated using the National Institutes of Health-Chronic Pro...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Wei-Jie Song Ji-Wei Huang Yuan Liu Wei Ding Zhi Long Le-Ye He Source Type: research

The Changing Landscape of Global Child Health Education in the United States and the Effects of the COVID-19 Pandemic and Civil Unrest
Pediatr Ann. 2023 Sep;52(9):e324-e329. doi: 10.3928/19382359-20230720-02. Epub 2023 Sep 1.ABSTRACTThe events of recent years have affected the landscape of global child health education (GCHE) in the United States. War, racism, forced displacement, and the coronavirus disease 2019 (COVID-19) pandemic had global repercussions that reached US GCHE. The aim of this article is to examine the effect of these events on the landscape of GCHE in the US. Key areas of GCHE have been reframed, reshaped, and accelerated by these events. Travel restrictions accelerated virtual learning opportunities. Core curriculum needed to be recons...
Source: Pediatric Annals - September 11, 2023 Category: Pediatrics Authors: Ashley Bjorklund Mounika Muttineni Sophia Gladding Tina Slusher Cynthia R Howard Source Type: research

Human Respiratory Syncytial Virus and Coronavirus Rates in Iranian Elderly Patients More than 60 Years Old with Acute Respiratory Symptoms
CONCLUSIONS: It seems that during the pandemic of COVID-19, RSV should not be ignored as it can be responsible for the respiratory syndrome.PMID:37694251 | PMC:PMC10492601 | DOI:10.4103/abr.abr_395_22
Source: Biomed Res - September 11, 2023 Category: Research Authors: Shaian Tavakolian Hossein Goudarzi Ilad Alavi Darazam Ebrahim Faghihloo Source Type: research

Metformin and Covid-19: a systematic review of systematic reviews with meta-analysis
Conclusions More in-depth studies on the use of metformin, compared to other molecules, may be required to understand the real protective potential of the drug against negative outcomes caused by COVID-19 infection in DM2 patients.PMID:37695186 | DOI:10.23750/abm.v94iS3.14405
Source: Acta Bio-Medica : Atenei Parmensis - September 11, 2023 Category: General Medicine Authors: Fabio Petrelli Iolanda Grappasonni Cuc Thi Thu Nguyen Marina Tesauro Paola Pantanetti Sonila Xhafa Giovanni Cangelosi Source Type: research

Prognostic factors for poor outcomes in patients with severe COVID-19 treated with remdesivir plus dexamethasone in Taiwan
CONCLUSION: High disease severity on admission and delayed initiation of remdesivir therapy were associated with poor outcomes in COVID-19 patients treated with remdesivir and dexamethasone.PMID:37696685 | DOI:10.1016/j.jmii.2023.08.008
Source: Journal of Microbiology, Immunology, and Infection - September 11, 2023 Category: Microbiology Authors: Yi-Hsuan Lai Yi-Chih Lee I-Ren Chen Shih-Neng Lin Yuh-Lih Chang Chih-Chia Lu Ping-Feng Wu Yi-Tsung Lin Source Type: research

The impact of the COVID-19 pandemic on erectile function in Chinese CP/CPPS patients
This study aimed to investigate the impact of the coronavirus disease 2019 (COVID-19) pandemic on erectile function in Chinese patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). A retrospective study was conducted on 657 CP/CPPS patients who visited The Third Xiangya Hospital of Central South University (Changsha, China) from November 2018 to November 2022. Patients were divided into two groups based on the timeline before and after the COVID-19 outbreak in China. The severity of CP/CPPS, penile erection status, anxiety, and depression was evaluated using the National Institutes of Health-Chronic Pro...
Source: Asian Journal of Andrology - September 11, 2023 Category: Urology & Nephrology Authors: Wei-Jie Song Ji-Wei Huang Yuan Liu Wei Ding Zhi Long Le-Ye He Source Type: research

Prognostic factors for poor outcomes in patients with severe COVID-19 treated with remdesivir plus dexamethasone in Taiwan
CONCLUSION: High disease severity on admission and delayed initiation of remdesivir therapy were associated with poor outcomes in COVID-19 patients treated with remdesivir and dexamethasone.PMID:37696685 | DOI:10.1016/j.jmii.2023.08.008
Source: Journal of Microbiology, Immunology, and Infection - September 11, 2023 Category: Microbiology Authors: Yi-Hsuan Lai Yi-Chih Lee I-Ren Chen Shih-Neng Lin Yuh-Lih Chang Chih-Chia Lu Ping-Feng Wu Yi-Tsung Lin Source Type: research

Recombination in sarbecovirus lineage and mutations/insertions in spike protein are linked to the emergence and adaptation of SARS-CoV-2
Bioinformation. 2022 Oct 31;18(10):951-961. doi: 10.6026/97320630018951. eCollection 2022.ABSTRACTThe outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan city, China in December 2019 and thereafter its spillover across the world has created a global pandemic and public health crisis. Right after, there has been intense interest in understanding how the SARS-CoV-2 originated and evolved. This paper also aims to shed light on the origin and evolution of SARS-CoV- 2. A consensus result based on whole genome phylogeny, gene tree analysis, and genetic similarity study revealed that SARS-CoV-2 evolv...
Source: Bioinformation - September 11, 2023 Category: Bioinformatics Authors: Anup Som Amresh Kumar Sharma Priyanka Kumari Source Type: research

Identifying luteolin as a potential drug for treating lung adenocarcinoma with COVID-19 affection based on integration analysis of pharmacology and transcriptome
CONCLUSION: HSP90AA1 was a target gene for further designing effective drugs for LUAD patients. Luteolin was a potential drug for treating patients with both LUAD and COVID-19.PMID:37694790 | DOI:10.2174/0929867331666230908090326
Source: Current Medicinal Chemistry - September 11, 2023 Category: Chemistry Authors: Ping Peng Na Li Ni Zhang Xiangning Fu Shu Peng Yujie Zhao Bo Ai Source Type: research

The Changing Landscape of Global Child Health Education in the United States and the Effects of the COVID-19 Pandemic and Civil Unrest
Pediatr Ann. 2023 Sep;52(9):e324-e329. doi: 10.3928/19382359-20230720-02. Epub 2023 Sep 1.ABSTRACTThe events of recent years have affected the landscape of global child health education (GCHE) in the United States. War, racism, forced displacement, and the coronavirus disease 2019 (COVID-19) pandemic had global repercussions that reached US GCHE. The aim of this article is to examine the effect of these events on the landscape of GCHE in the US. Key areas of GCHE have been reframed, reshaped, and accelerated by these events. Travel restrictions accelerated virtual learning opportunities. Core curriculum needed to be recons...
Source: Pediatric Annals - September 11, 2023 Category: Pediatrics Authors: Ashley Bjorklund Mounika Muttineni Sophia Gladding Tina Slusher Cynthia R Howard Source Type: research