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Infectious Disease: Endemics
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Total 16411 results found since Jan 2013.
Clinical Characteristics and Outcomes of Chagas Disease in the United States: A Multicenter Retrospective Analysis
Am J Trop Med Hyg. 2023 Sep 11:tpmd230361. doi: 10.4269/ajtmh.23-0361. Online ahead of print.ABSTRACTChagas disease affects approximately 300,000 patients in the United States. We evaluated a multicenter U.S.-based network to obtain clinical characteristics and outcomes of chronic Chagas disease by disease forms. This was a U.S.-based, multicenter, population-based, retrospective cohort study. We queried TriNetX, a global research network, to identify patients with dual-positive IgG serology for Trypanosoma cruzi. We captured outcomes of interest for up to 5 years. We found 429 patients with evidence of dual-positive T. cr...
Source: Am J Trop Med Hyg - September 11, 2023 Category: Infectious Diseases Authors: Andr és F Henao-Martínez Christian Olivo-Freites Nelson I Agudelo Higuita Carolina Ferraz Carlos Franco-Paredes Jose Tuells Laila Woc-Colburn Salvador Villalpando-Carri ón Daniel B Chastain Anis Rassi Source Type: research
Chikungunya virus virus-like particle vaccine is well tolerated and immunogenic in chikungunya seropositive individuals
Vaccine. 2023 Sep 8:S0264-410X(23)01052-6. doi: 10.1016/j.vaccine.2023.08.086. Online ahead of print.ABSTRACTIn a phase 2 safety and immunogenicity study of a chikungunya virus virus-like particle (CHIKV VLP) vaccine in an endemic region, of 400 total participants, 78 were found to be focus reduction neutralizing antibody seropositive at vaccination despite being ELISA seronegative at screening, of which 39 received vaccine. This post hoc analysis compared safety and immunogenicity of CHIKV VLP vaccine in seropositive (n = 39) versus seronegative (n = 155) vaccine recipients for 72 weeks post-vaccination. There were no dif...
Source: Vaccine - September 10, 2023 Category: Allergy & Immunology Authors: James M McCarty Lisa Bedell Jason Mendy Emily E Coates Grace L Chen Julie E Ledgerwood Sarah Royalty Tredo Kelly L Warfield Jason S Richardson Source Type: research
Desalination brine effects beyond excess salinity: Unravelling specific stress signaling and tolerance responses in the seagrass Posidonia oceanica
This study revealed that although metabolic and photochemical differences occurred under both hypersalinity treatments, growth (the last sign of physiological detriment) was similarly compromised, suggesting that the potential effects of desalination are mainly caused by brine-associated salinities and are not particularly related to other industrial additives.PMID:37689149 | DOI:10.1016/j.chemosphere.2023.140061
Source: Chemosphere - September 9, 2023 Category: Chemistry Authors: Fabio Blanco-Murillo L ázaro Marín-Guirao Iv án Sola Fernanda Rodr íguez-Rojas Juan M Ruiz Jos é Luis Sánchez-Lizaso Claudio A S áez Source Type: research
Multi-omics reveal mechanisms underlying chronic kidney disease of unknown etiology (CKDu) pathogenesis using zebrafish
Environ Pollut. 2023 Sep 6:122524. doi: 10.1016/j.envpol.2023.122524. Online ahead of print.ABSTRACTChronic kidney disease of unknown etiology (CKDu) is an endemic disease in the dry zone of farming communities, Sri Lanka. The drinking water in a CKDu prevalent area contains a high concentration of F- and hardness, and other environmental pollutants, including heavy metals and microcystin, which are considered possible etiology of CKDu in these areas. Here, multi-omics data with host transcriptome, metabolome, and gut microbiomes were obtained using simulated local drinking water of Sri Lanka after their exposure to adult ...
Source: Environmental Pollution - September 8, 2023 Category: Environmental Health Authors: Xing-Yi Wei Pan-Pan Jia Huan Hu Li Liu Tian-Yun Li Yong-Zhi Li De-Sheng Pei Source Type: research
Outbreak of Locally Acquired Mosquito-Transmitted (Autochthonous) Malaria - Florida and Texas, May-July 2023
MMWR Morb Mortal Wkly Rep. 2023 Sep 8;72(36):973-978. doi: 10.15585/mmwr.mm7236a1.ABSTRACTEight cases of locally acquired, mosquito-transmitted (i.e., autochthonous) Plasmodium vivax malaria, which has not been reported in the United States since 2003, were reported to CDC from state health departments in Florida and Texas during May 18-July 17, 2023. As of August 4, 2023, case surveillance, mosquito surveillance and control activities, and public outreach and education activities continue in both states. U.S. clinicians need to consider a malaria diagnosis in patients with unexplained fever, especially in areas where auto...
Source: MMWR Morb Mortal Wkl... - September 7, 2023 Category: Epidemiology Authors: Dawn Blackburn Michael Drennon Kelly Broussard Andrea M Morrison Danielle Stanek Elizabeth Sarney Christina Ferracci Steve Huard Wade Brennan John Eaton Sara Nealeigh Natalie Barber Rebecca A Zimler Jeremy N Adams Carina Blackmore Manuel Gordillo Robert M Source Type: research
Development of a quadrivalent foot-and-mouth disease vaccine candidate for use in East Africa
Vaccine. 2023 Sep 5:S0264-410X(23)01054-X. doi: 10.1016/j.vaccine.2023.08.088. Online ahead of print.ABSTRACTFoot-and-mouth disease (FMD) is a highly contagious viral disease of livestock which is prevalent across Africa, the Middle East, Asia, and South America where it has a severe economic impact on the agriculture industry. Vaccination with inactivated viral vaccines is used as the main control measure in these endemic regions of the world, however the presence of multiple serotypes, subtypes, and the continual emergence of new, antigenically divergent strains limits its effectiveness. East Africa (EA) has been identif...
Source: Vaccine - September 7, 2023 Category: Allergy & Immunology Authors: Kay Childs Yongjie Harvey Ryan Waters Timothy Woma Ginette Wilsden Hualu Sun Peng Sun Julian Seago Source Type: research
Outbreak of Locally Acquired Mosquito-Transmitted (Autochthonous) Malaria - Florida and Texas, May-July 2023
MMWR Morb Mortal Wkly Rep. 2023 Sep 8;72(36):973-978. doi: 10.15585/mmwr.mm7236a1.ABSTRACTEight cases of locally acquired, mosquito-transmitted (i.e., autochthonous) Plasmodium vivax malaria, which has not been reported in the United States since 2003, were reported to CDC from state health departments in Florida and Texas during May 18-July 17, 2023. As of August 4, 2023, case surveillance, mosquito surveillance and control activities, and public outreach and education activities continue in both states. U.S. clinicians need to consider a malaria diagnosis in patients with unexplained fever, especially in areas where auto...
Source: MMWR Morb Mortal Wkl... - September 7, 2023 Category: Epidemiology Authors: Dawn Blackburn Michael Drennon Kelly Broussard Andrea M Morrison Danielle Stanek Elizabeth Sarney Christina Ferracci Steve Huard Wade Brennan John Eaton Sara Nealeigh Natalie Barber Rebecca A Zimler Jeremy N Adams Carina Blackmore Manuel Gordillo Robert M Source Type: research
Development of a quadrivalent foot-and-mouth disease vaccine candidate for use in East Africa
Vaccine. 2023 Sep 5:S0264-410X(23)01054-X. doi: 10.1016/j.vaccine.2023.08.088. Online ahead of print.ABSTRACTFoot-and-mouth disease (FMD) is a highly contagious viral disease of livestock which is prevalent across Africa, the Middle East, Asia, and South America where it has a severe economic impact on the agriculture industry. Vaccination with inactivated viral vaccines is used as the main control measure in these endemic regions of the world, however the presence of multiple serotypes, subtypes, and the continual emergence of new, antigenically divergent strains limits its effectiveness. East Africa (EA) has been identif...
Source: Vaccine - September 7, 2023 Category: Allergy & Immunology Authors: Kay Childs Yongjie Harvey Ryan Waters Timothy Woma Ginette Wilsden Hualu Sun Peng Sun Julian Seago Source Type: research
Outbreak of Locally Acquired Mosquito-Transmitted (Autochthonous) Malaria - Florida and Texas, May-July 2023
MMWR Morb Mortal Wkly Rep. 2023 Sep 8;72(36):973-978. doi: 10.15585/mmwr.mm7236a1.ABSTRACTEight cases of locally acquired, mosquito-transmitted (i.e., autochthonous) Plasmodium vivax malaria, which has not been reported in the United States since 2003, were reported to CDC from state health departments in Florida and Texas during May 18-July 17, 2023. As of August 4, 2023, case surveillance, mosquito surveillance and control activities, and public outreach and education activities continue in both states. U.S. clinicians need to consider a malaria diagnosis in patients with unexplained fever, especially in areas where auto...
Source: MMWR Morb Mortal Wkl... - September 7, 2023 Category: Epidemiology Authors: Dawn Blackburn Michael Drennon Kelly Broussard Andrea M Morrison Danielle Stanek Elizabeth Sarney Christina Ferracci Steve Huard Wade Brennan John Eaton Sara Nealeigh Natalie Barber Rebecca A Zimler Jeremy N Adams Carina Blackmore Manuel Gordillo Robert M Source Type: research
Chronic Interstitial Nephritis in Agricultural Communities: Observational and Mechanistic Evidence Supporting the Role of Nephrotoxic Agrochemicals
Clin J Am Soc Nephrol. 2023 Sep 6. doi: 10.2215/CJN.0000000000000312. Online ahead of print.ABSTRACTChronic interstitial nephritis in agricultural communities (CINAC) is an epidemic of kidney disease affecting specific tropical and subtropical regions worldwide and is characterized by progressive chronic kidney disease (CKD) in the absence of traditional risk factors such as hypertension and diabetes. CINAC prevalence is higher among young, male agricultural workers, but also affects women, children, and non-agricultural workers in affected areas. Biopsies from patients with CINAC across regions commonly demonstrate tubula...
Source: Clinical Journal of the American Society of Nephrology : CJASN - September 7, 2023 Category: Urology & Nephrology Authors: Michael W Holliday Ravikumar Nagavenkata Majeti David Sheikh-Hamad Source Type: research
