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Total 472 results found since Jan 2013.

XXIV World Allergy Congress 2015
Table of Contents A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts Jae-Min Shin, Heung-Man Lee, Il-Ho Park A2 The efficacy of a 2-week course of oral steroid in the treatment of chronic spontaneous urticaria refractory to antihistamines Hyun-Sun Yoon, Gyeong Yul Park A3 The altered distribution of follicular t helper cells may predict a more pronounced clinical course of primary sjögren’s syndrome Margit Zeher A4 Betamethasone suppresses Th2 cell development induced by langerhans cell like dendr...
Source: World Allergy Organization Journal - April 18, 2016 Category: Allergy & Immunology Source Type: research

Allergy evaluation of hypersensitivity to platinium salts and taxanes: a six-year experience.
ConclusionsST to PS or TX offered a high NPV, making allergy evaluation a key element in the management of cancer patients. Graded challenges can be safely performed by oncology teams trained in anaphylaxis management.
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 7, 2020 Category: Allergy & Immunology Source Type: research

M021 multiple chemotherapy medication allergy in a patient with recurrent ovarian cancer
We present a patient with recurrent ovarian cancer complicated by multiple chemotherapy drug allergy to Bevacizumab, Taxol, Carboplatin, Oxaliplatin, Cisplatin, and Gemcitabine.
Source: Annals of Allergy, Asthma and Immunology - November 1, 2021 Category: Allergy & Immunology Authors: Y. Jung, A. Naderi Source Type: research

European Allergy Task Force Provides Clinical Guidance on Chemotherapy European Allergy Task Force Provides Clinical Guidance on Chemotherapy
All chemotherapy agents can induce hypersensitivity reactions, but the authors of a European position paper say there is little agreement on how to investigate the cause of the reactions and treat them.Medscape Medical News
Source: Medscape Allergy Headlines - February 4, 2022 Category: Allergy & Immunology Tags: Allergy & Clinical Immunology News Source Type: news

Allergy Task Force Provides Clinical Guidance on Chemotherapy Allergy Task Force Provides Clinical Guidance on Chemotherapy
Authors offer consensus recommendations from a literature review on areas including causes and treatments.Medscape Medical News
Source: Medscape Allergy Headlines - February 4, 2022 Category: Allergy & Immunology Tags: Allergy & Clinical Immunology News Source Type: news

Drug allergy biomarkers
Although the true burden of drug allergy is unknown, several studies indicate that adverse drug reactions occur in up to 6% to 10% of hospitalized patients —20% of which are because of drug allergy—and up to 10% of the general population claims to have penicillin or other drug allergies.1 A plethora of new antibiotics, vaccines, chemotherapy drugs, and, more recently, biologicals and targeted molecular drugs are available and have improved disease treatment options, but drug allergy remains a vexing and unaddressed problem that deprives patients of the best medication for their disease, and when re-exposed, places them...
Source: Annals of Allergy, Asthma and Immunology - February 1, 2023 Category: Allergy & Immunology Authors: Mariana Castells Tags: Editorial Source Type: research

Prognosis for sixth nerve palsy arising from paranasal sinus disease.
CONCLUSION: Paranasal sinus pathology is a rare cause of CNVI palsy. A number of factors may help to predict prognosis in these patients. Masses compressing, but not destroying or invading, the cavernous sinus had optimal posttreatment outcomes with full resolution occurring as early as 2 weeks. Destructive lesions that invaded CNVI and its vasculature, i.e., invasive fungus, were negative indicators for recovery. Knowledge of factors that affect recovery can help clinicians predict disease course and prognosis for resolution of the defect. PMID: 24119609 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - September 1, 2013 Category: ENT & OMF Authors: Miller C, Suh JD, Henriquez OA, Schlosser RJ, Ramakrishnan VR, Chiu AG Tags: Am J Rhinol Allergy Source Type: research

Targeting Inflammation in Cancer-Related-Fatigue: A Rationale for Mistletoe Therapy as Supportive Care in Colorectal Cancer Patients.
Conclusion. The clinically used mistletoe medication (Iscador®Qu) is the first candidate to be included in a supportive care modus into chemo- or chemo-radiotherapy protocols for colorectal patients to improve CRF without discernable toxicities. PMID: 24766319 [PubMed - as supplied by publisher]
Source: Inflammation and Allergy Drug Targets - April 27, 2014 Category: Allergy & Immunology Authors: Bock PR, Hanisch J, Matthes H, Zanker KS Tags: Inflamm Allergy Drug Targets Source Type: research

Desensitization for hypersensitivity reactions to medications.
Authors: del Carmen Sancho M, Breslow R, Sloane D, Castells M Abstract Rapid drug desensitization (RDD) is a technique that induces temporary tolerance to a drug, allowing a medication-allergic patient to receive the optimal agent for his or her disease. Through RDD, patients with IgE and non-IgE hypersensitivity reactions (HSRs) including anaphylaxis can safely be administered important medications while minimizing or completely inhibiting adverse reactions. Adverse reactions to drugs are increasingly recognized as important contributors to disease as well as impediments to the best treatment of dermatological, in...
Source: Chemical Immunology and Allergy - December 2, 2014 Category: Allergy & Immunology Tags: Chem Immunol Allergy Source Type: research

Cutaneous drug eruptions associated with the use of new oncological drugs.
Authors: Belloni B, Schönewolf N, Rozati S, Goldinger SM, Dummer R Abstract There is a variety of adverse effects and toxicities of newer and older chemotherapeutic agents which emerge in the skin, mucosa and adnexa. Common skin reactions while undergoing chemotherapy include alopecia, changes in skin pigmentation, palmoplantar erythrodysesthesia, nail dystrophies and stomatitis. Extravasation injuries or hypersensitivity reactions may be severe. New oncologic agents have led to the development of different, class-specific cutaneous side effects. Epidermal growth factor receptor (EGFR) inhibitors induce papulopust...
Source: Chemical Immunology and Allergy - December 2, 2014 Category: Allergy & Immunology Tags: Chem Immunol Allergy Source Type: research

Comparative analysis of quality-of-life metrics after endoscopic surgery for sinonasal neoplasms.
CONCLUSION: Patients who have undergone endoscopic resection of sinonasal tumors have quantifiable QOL changes as measured by various validated metrics. This study shows that concurrent use of these instruments may better discern QOL outcomes after endoscopic tumor surgery. PMID: 25785758 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - March 1, 2015 Category: ENT & OMF Authors: Deckard NA, Harrow BR, Barnett SL, Batra PS Tags: Am J Rhinol Allergy Source Type: research

Nasal cytological changes as late effects of radiotherapy for nasopharyngeal cancer.
CONCLUSION: Radiation therapy induces late nasal mucosal changes, which may be related to clinical consequences, such as abundant mucus production and its consequent endonasal stagnation. In the future, detailed knowledge of cytological changes in patients' nasal mucosa could represent a key prerequisite for the choice of effective interventions for late radiation-induced rhinitis. PMID: 25785741 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - March 1, 2015 Category: ENT & OMF Authors: Riva G, Boita M, Ravera M, Moretto F, Badellino S, Rampino M, Ricardi U, Pecorari G, Garzaro M Tags: Am J Rhinol Allergy Source Type: research

Formulation of Nanoparicles Against TB - A Review.
Authors: Kataria M, Sethi M, Kaur J, Punia S, Kumar K Abstract Tuberculosis is a major public health concern. The present article reviews the current updates on the usage of nanoparticles against tuberculosis and recent patents that could develop into novel therapeutics available to the clinical armamentarium for the TB management. The drug delivery systems involving nanoparticles are suitable against chronic diseases such as tuberculosis. Polymers in many forms like liposomes, dendrimers, Nanoemulsions can be used as synthetic and natural carriers for first line and second line drugs employed for chemotherapy. Not...
Source: Recent Patents on Inflammation and Allergy Drug Discovery - September 30, 2015 Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research

The Hidden Culprit: A Case of Repeated Anaphylaxis to Cremophor.
We report a case of lung cancer patient who experienced two near-fatal anaphylactic reactions that resulted from paclitaxel and multivitamin, seperately. Recurrent severe reactions to different agents led to further investigation to which material the patient was hypersensitive. The skin prick test revealed sensitization to cremophor, which is a commonly used emulsifying agent. This case emphasizes the importance of correctly identifying the culprit drug of anaphylaxis to avoid potentially fatal reaction. PMID: 26739412 [PubMed]
Source: Allergy, Asthma and Immunology Research - January 16, 2016 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Lymphoma of the nasal cavity and paranasal sinuses: A case series.
CONCLUSION: Sinonasal lymphomas are characterized by meager survival rates, which differ by histopathologic subtype. The diagnosis of sinonasal lymphoma is challenging because symptoms frequently parallel those of chronic rhinosinusitis. Increased awareness of these rare malignancies may improve detection and more timely treatment. Clinical trial registration NCT01332136. PMID: 27657899 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - August 31, 2016 Category: ENT & OMF Authors: Steele TO, Buniel MC, Mace JC, El Rassi E, Smith TL Tags: Am J Rhinol Allergy Source Type: research