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Penicillin allergy status and its effect on antibiotic prescribing, patient outcomes and antimicrobial resistance (ALABAMA): protocol for a multicentre, parallel-arm, open-label, randomised pragmatic trial
Introduction Incorrect penicillin allergy records are recognised as an important barrier to the safe treatment of infection and affect an estimated 2.7 million people in England. Penicillin allergy records are associated with worse health outcome and antimicrobial resistance. The ALlergy AntiBiotics And Microbial resistAnce (ALABAMA) trial aims to determine if an intervention package, centred around a penicillin allergy assessment pathway (PAAP) initiated in primary care, is safe and effective in improving patient health outcomes and antibiotic prescribing. Methods and analysis The ALABAMA trial is a multicentre, parallel...
Source: BMJ Open - September 4, 2023 Category: General Medicine Authors: Armitage, K. F., Porter, C. E., Ahmed, S., Cook, J., Boards, J., Bongard, E., Butler, C. C., Corfield, K., Davoudianfar, M., Galal, U., Howard, P., Mujica-Mota, R., Saman, R., Santillo, M., Savic, S., Shinkins, B., Tonkin-Crine, S., Wanat, M., West, R. M. Tags: Open access, Infectious diseases Source Type: research

Healthcare professionals' attitudes to penicillin allergy labels
CONCLUSIONS: The penicillin allergy label is an independent factor of medication errors. Solutions to enhance patient safety may include education of physicians in allergy labelling, decision support, standardisation of the allergy registration in the various EMR systems used, and ideally also a national drug allergy register, which is accessible from all sectors.FUNDING: None.TRIAL REGISTRATION: Not relevant.PMID:37622646
Source: Danish Medical Journal - August 25, 2023 Category: General Medicine Authors: Ida Josephine Raun Pernille Bach Tengberg Tom M øller Lene Heise Garvey Source Type: research

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