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Total 388 results found since Jan 2013.

Emergence of Marburg virus: a global perspective on fatal outbreaks and clinical challenges
The Marburg virus (MV), identified in 1967, has caused deadly outbreaks worldwide, the mortality rate of Marburg virus disease (MVD) varies depending on the outbreak and virus strain, but the average case fatality rate is around 50%. However, case fatality rates have varied from 24 to 88% in past outbreaks depending on virus strain and case management. Designated a priority pathogen by the National Institute of Allergy and Infectious Diseases (NIAID), MV induces hemorrhagic fever, organ failure, and coagulation issues in both humans and non-human primates. This review presents an extensive exploration of MVD outbreak evolu...
Source: Frontiers in Microbiology - September 13, 2023 Category: Microbiology Source Type: research

The Predictors of Hepatorenal Syndrome Development in HCV Cirrhotic Ascitic Egyptian Patients with Spontaneous Bacterial Peritonitis
Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry - September 7, 2023 Category: Allergy & Immunology Authors: El Sharawy, Shimaa M. Elkadeem, Mahmoud Zaki Amer, Ibrahim Fathi Tags: Research article Source Type: research

Marginal Zone
Cartootorial: In 1930, LA Wadell reported that Pharaoh Menes of Egypt died in 2641 BCE of insect sting anaphylaxis, a fact that has oft been repeated in the Allergy literature.1,2 While intriguing, this isn't supported by other historians.1 –3 Wadell's claim was based on his own interpretation of hieroglyphs from a purported burial site for Menes, which he said depicted wasps.1,2 In contrast, Manetho, a 3rd century BCE priest and Egyptian historian, wrote extensively about Menes, stating he “was carried off by a hippopotamus and pe rished.”2,3 Modern historians have noted similarities in hieroglyphs used to depict wa...
Source: Annals of Allergy, Asthma and Immunology - August 1, 2023 Category: Allergy & Immunology Authors: Erin L. Reigh Tags: Marginal Zone Source Type: research

Association of serum CD14 level and functional polymorphism C-159T in the promoter region of CD14 gene with allergic rhinitis
This study aimed to determine the associat ion between C-159T polymorphism in the CD14 gene promoter region and serum CD14 levels and the risk of Allergic rhinitis Egyptian patients and to test the validity of serum CD14 level measurement in predicting AR. This case–control study included 45 patients with AR referred to Allergy and Immunol ogy Unit, Zagazig University Hospital, Zagazig, Egypt, and 45 healthy subjects as controls. Serum CD14 levels were measured by ELISA. The polymerase chain reaction-restriction fragment length polymorphism technique was used to detect C-159T gene polymorphism in the CD14 promoter region...
Source: Clinical and Experimental Medicine - June 7, 2023 Category: Research Source Type: research

Immunological and molecular study in children with combined immunodeficiency
Conclusions. To evaluate SCID patients completely; mutation gene analysis is highly required and recommended.PMID:36786340 | DOI:10.23822/EurAnnACI.1764-1489.286
Source: European Annals of Allergy and Clinical Immunology - February 14, 2023 Category: Allergy & Immunology Authors: S Kholoussi A Ramadan N Kholoussi E A Ashaat A G Fayez H A Raouf I Helwa N N Esmaiel R Ghorab A M Abo-Shanab Source Type: research