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Total 80037 results found since Jan 2013.
Nonlinear Neural Patterns Are Revealed In High Frequency Functional Near Infrared Spectroscopy Analysis
Brain Res Bull. 2023 Sep 14:110759. doi: 10.1016/j.brainresbull.2023.110759. Online ahead of print.ABSTRACTFunctional Near Infrared Spectroscopy (fNIRS) is a useful tool for measuring hemoglobin concentration. Linear theory of the hemodynamic response function supports low frequency analysis ( < 0.2 Hz). However, we hypothesized that nonlinearities, arising from the complex neurovascular interactions sustaining vasomotor tone, may be revealed in higher frequency components of fNIRS signals. To test this hypothesis, we simulated nonlinear hemodynamic models to explore how blood flow autoregulation changes may alter evoke...
Source: Brain Research - September 16, 2023 Category: Neurology Authors: Ameer Ghouse Diego Candia Rivera Gaetano Valenza Source Type: research
Chronic memantine disrupts spatial memory and up-regulates Htr1a gene expression in the hippocampus of GPR39 (zinc-sensing receptor) KO male mice
We report: no effects of acute memantine on ELM; a tendency to improve the "where?" component of ELM in both WT and GPR39 KO mice following 12 days of memantine; and, a disruption of SM in GPR39KO mice after 24 days of memantine treatment. The latter result was associated with upregulation of Htr1a hippocampal expression.PMID:37716463 | DOI:10.1016/j.brainres.2023.148577
Source: Brain Research - September 16, 2023 Category: Neurology Authors: Michal Rychlik Joanna Starnowska-Sokol Katarzyna Mlyniec Source Type: research
Cognitive function and the longitudinal hippocampal axis in mesial temporal sclerosis
CONCLUSIONS: Ipsilateral hippocampal head and tail seem more vulnerable to injury than the body in both the left and right mTLE. Our study suggests there may be functional differences along the hippocampal longitudinal axis, particularly for the left hippocampal tail with verbal memory. Our findings are consistent with material-specific right-left differences in memory processing.PMID:37716331 | DOI:10.1016/j.yebeh.2023.109413
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: L Reppert L N Sepeta D Panjeti-Moore E Akinsoji C Sherer A Hamidullah-Thiam W H Theodore Source Type: research
Referral odyssey plot to visualize causes of surgical delay in mesial temporal lobe epilepsy with hippocampal sclerosis
Epilepsy Behav. 2023 Sep 14;147:109434. doi: 10.1016/j.yebeh.2023.109434. Online ahead of print.ABSTRACTThe "odyssey plot" was used to visualize referral delays in epilepsy surgery. Participants were 36 patients (19 males; 13-67 years, median 27 years) with mesial temporal lobe epilepsy with hippocampal sclerosis (HS) who underwent resection surgery. The "referral odyssey plot" included five clinical episodes: seizure onset (T1), first visits to a non-epileptologist (T2) and to an epileptologist (T3), first admission to our epilepsy monitoring unit (EMU) (T4), and resection surgery (T5). For each patient, we identified the...
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Kazutoshi Konomatsu Yosuke Kakisaka Makoto Ishida Temma Soga Kazushi Ukishiro Shin-Ichiro Osawa Kazutaka Jin Masashi Aoki Nobukazu Nakasato Source Type: research
Risk of suicide and religious or spiritual beliefs in Brazilian adult patients with epilepsy
DISCUSSION: A high number of patients with epilepsy exhibited suicide risk, with epilepsy-related variables, the presence of anxiety, and perceived lower belongingness and social support from religiosity or spirituality anxiety being associated with a higher risk. The social support provided by religiosity/spirituality may be a non-clinical factor associated with suicidal behavior. Suicide in epilepsy is associated with a complex interaction of multidimensional factors.PMID:37716329 | DOI:10.1016/j.yebeh.2023.109414
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Yasmin Meneguci Petrarca Gl ória M A S Tedrus Source Type: research
Hypothalamic hamartoma surgery in a setting with limited resources
CONCLUSION: Hypothalamic hamartoma surgery is feasible even in centers with limited resources if a close collaboration exists between the epileptology and neurosurgery teams. Careful planning based on the expertise of the team members and the available resources is required to foster success.PMID:37716328 | DOI:10.1016/j.yebeh.2023.109439
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Ali A Asadi-Pooya Mohamad S Masoudi Bita Hashemi Seyedarad Mosalamiaghili Masoume Nazeri Khatereh Fazelian Source Type: research
Reliability and validation of the Chinese version of the epilepsy surgery satisfaction questionnaire
CONCLUSIONS: The C-ESSQ-19 has proven to be a reliable and valid self-rated questionnaire for assessing the satisfaction of Chinese mainland epilepsy patients with surgery.PMID:37716327 | DOI:10.1016/j.yebeh.2023.109438
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Qun Yu Yu-Qi Ying Si-Xuan Jiang Zheng-Yan-Ran Xu Mei-Juan Lan Yi Guo Source Type: research
Co-production of online educational resources for adolescent and young adult females with epilepsy
CONCLUSION: Our team utilized co-production with a diverse group of partners to create educational materials that met the interests of adolescent and young adult females with epilepsy. This is a structured and reproducible methodology that could inform future educational intervention development in epilepsy.PMID:37716326 | DOI:10.1016/j.yebeh.2023.109420
Source: Epilepsy and Behaviour - September 16, 2023 Category: Neurology Authors: Medha Parulekar Traci M Kazmerski Danielle Gordon Tahniat Syed Janet F R Waters Anne C Van Cott Laura Kirkpatrick Source Type: research
Microvascular blood-brain barrier alterations in isolated brain capillaries of mice over-expressing alpha-synuclein (Thy1-aSyn line 61)
Neurobiol Dis. 2023 Sep 14:106298. doi: 10.1016/j.nbd.2023.106298. Online ahead of print.ABSTRACTDysfunction of the blood-brain barrier (BBB) is suggested to play a critical role in the pathological mechanisms of Parkinson's disease (PD). PD-related pathology such as alpha-synuclein accumulation and inflammatory processes potentially affect the integrity of the BBB early in disease progression, which in turn may alter the crosstalk of the central and peripheral immune response. Importantly, BBB dysfunction could also affect drug response in PD. Here we analyzed microvascular changes in isolated brain capillaries and brain ...
Source: Neurobiology of Disease - September 16, 2023 Category: Neurology Authors: Kristina Lau Lisa T Porschen Franziska Richter Birthe Gericke Source Type: research
Aberrant splicing of mutant huntingtin in Huntington's disease knock-in pigs
In this study, HTT exon1 production was examined in the HD knock-in (KI) pig model, which more closely recapitulates neuropathology seen in HD patient brains than HD mouse models. The study revealed that aberrant spliced HTT exon1 is also present in the brains of HD pigs, but it is expressed at a much lower level than the normally spliced HTT exon products. These findings suggest that careful consideration is needed when assessing the contribution of aberrantly spliced mHTT exon1 to HD pathogenesis, and further rigorous investigation is required.PMID:37716514 | DOI:10.1016/j.nbd.2023.106291
Source: Neurobiology of Disease - September 16, 2023 Category: Neurology Authors: Huichun Tong Tianqi Yang Li Liu Caijuan Li Yize Sun Qingqing Jia Yiyang Qin Laiqiang Chen Xianxian Zhao Gongke Zhou Sen Yan Xiao-Jiang Li Shihua Li Source Type: research
The value of continuing research on epidemiology of cerebral palsy (CP) - What have we learned?
Eur J Paediatr Neurol. 2023 Sep 9:S1090-3798(23)00137-X. doi: 10.1016/j.ejpn.2023.09.004. Online ahead of print.NO ABSTRACTPMID:37716822 | DOI:10.1016/j.ejpn.2023.09.004
Source: European Journal of Paediatric Neurology - September 16, 2023 Category: Neurology Authors: Antigone S Papavasiliou Dimitrios Zafeiriou Source Type: research
Metacognition and sense of agency
Cognition. 2023 Sep 14;241:105622. doi: 10.1016/j.cognition.2023.105622. Online ahead of print.ABSTRACTIntelligent agents need to understand how they can change the world, and how they cannot change it, in order to make rational decisions for their forthcoming actions, and to adapt to their current environment. Previous research on the sense of agency, based largely on subjective ratings, failed to dissociate the sensitivity of sense of agency (i.e., the extent to which individual sense of agency tracks actual instrumental control over external events) from judgment criteria (i.e., the extent to which individuals self-attr...
Source: Cognition - September 16, 2023 Category: Neurology Authors: Wen Wen Lucie Charles Patrick Haggard Source Type: research
Divergences in color perception between deep neural networks and humans
Cognition. 2023 Sep 14;241:105621. doi: 10.1016/j.cognition.2023.105621. Online ahead of print.ABSTRACTDeep neural networks (DNNs) are increasingly proposed as models of human vision, bolstered by their impressive performance on image classification and object recognition tasks. Yet, the extent to which DNNs capture fundamental aspects of human vision such as color perception remains unclear. Here, we develop novel experiments for evaluating the perceptual coherence of color embeddings in DNNs, and we assess how well these algorithms predict human color similarity judgments collected via an online survey. We find that stat...
Source: Cognition - September 16, 2023 Category: Neurology Authors: Ethan O Nadler Elise Darragh-Ford Bhargav Srinivasa Desikan Christian Conaway Mark Chu Tasker Hull Douglas Guilbeault Source Type: research
Multiple predictions during language comprehension: Friends, foes, or indifferent companions?
Cognition. 2023 Sep 14;241:105602. doi: 10.1016/j.cognition.2023.105602. Online ahead of print.ABSTRACTTo comprehend language, we continually use prior context to pre-activate expected upcoming information, resulting in facilitated processing of incoming words that confirm these predictions. But what are the consequences of disconfirming prior predictions? To address this question, most previous studies have examined unpredictable words appearing in contexts that constrain strongly for a single continuation. However, during natural language processing, it is far more common to encounter contexts that constrain for multiple...
Source: Cognition - September 16, 2023 Category: Neurology Authors: Trevor Brothers Emily Morgan Anthony Yacovone Gina Kuperberg Source Type: research
Effect of auditory deprivation on adaptive locomotion: Interaction with lower visual field occlusion
This study aimed to investigate whether auditory deprivation affects adaptive locomotion. In particular, we aimed to elucidate the role of the auditory sense in obstacle avoidance by manipulating the visual field, which provides crucial sensory information for movement control. Sixteen participants approached a 15-cm obstacle located 6m away and stepped over it under four different conditions that combined two factors: the hearing condition controlled by wearing earmuffs with and without holes, and the lower visual field condition controlled by carrying opaque white and transparent boards. Spatiotemporal variables during t...
Source: Brain Research - September 16, 2023 Category: Neurology Authors: Ryota Sakurai Yuka Miura Kentaro Kodama Masahiro Fujimoto Source Type: research
