Polycystic liver disease: An uncommon genetic condition
Key Clinical MessageTimely recognition, accurate diagnosis, and proper management are vital for preventing complications and improving outcomes in polycystic liver disease.AbstractPolycystic liver disease is an uncommon genetic condition characterized by the presence of over 20 liver cysts. It is symptomatic in only 5% of cases. Surgical intervention remains the primary treatment approach for managing symptoms in affected patients. Herein, we report a case of PLD revealed by severe abdominal pain. (Source: Clinical Case Reports)
Source: Clinical Case Reports - May 6, 2024 Category: General Medicine Authors: Faten Limaiem, Mohamed Hajri Tags: CASE IMAGE Source Type: research

DRESS syndrome without eosinophilia presented with extensive skin rash and acute respiratory failure
(Source: Clinical Case Reports)
Source: Clinical Case Reports - May 6, 2024 Category: General Medicine Authors: Nattanicha Chaisrimaneepan, Corley Pruneda, Marwan Elmassry, Mahmoud Abdelnabi Tags: CASE REPORT Source Type: research

Incidental diagnosis of silent extrahepatic portosystemic shunt
Key Clinical MessageExtrahepatic portosystemic shunts are a very rare disease. Early diagnosis and appropriate treatment are needed to prevent serious complications. In asymptomatic patients, conservative treatment is an option. (Source: Clinical Case Reports)
Source: Clinical Case Reports - May 6, 2024 Category: General Medicine Authors: Rhea Akel, Rany Aoun Tags: CASE IMAGE Source Type: research

A specific surgical procedure to remove the apices in the upper jaw
Key Clinical MessageThis clinical case report focuses on a case of surgery performed on a patient with the aim of cutting the dental apices in the patient's upper jaw. Mineral trioxide aggregate (MTA) was used as a filling material, and monitoring the condition showed that the operation was successful. (Source: Clinical Case Reports)
Source: Clinical Case Reports - May 6, 2024 Category: General Medicine Authors: Issa Saad, Marwan Al ‐Raeei, Mohamad Salem Rikab, Ahmad Al Manadili, Chadi Azmeh, Tala Alkhori, Remon Alhaja, Rama Kabani, Joudi Albokaii, Maya Saad Tags: CASE REPORT Source Type: research

Lindane and Cetrimide lotion poisoning in an adult patient: A case report on an uncommon ingestion
Key Clinical MessageLindane induces severe side effects, including fatality, while Cetrimide causes esophageal damage. With no antidotes available, our patient ingested both, requiring prompt gastric lavage and comprehensive treatment. (Source: Clinical Case Reports)
Source: Clinical Case Reports - May 6, 2024 Category: General Medicine Authors: Pragya Rai, Shrijan Shrestha, Suman Rijal, Rakesh Singh Tags: CASE REPORT Source Type: research

Multiple extreme overdose of antipsychotics with minimal side effects: A case report
Key Clinical MessageAntipsychotic drug treatment is a commonly used therapeutic strategy in the field of psychiatry. Rational and standardized use of antipsychotics is crucial in clinical practice, and excessive use of antipsychotics may lead to severe toxic reactions. Thus, attention should be given to the monitoring of drug concentration and examination of organ function.AbstractExcessive use of antipsychotics can cause a variety of adverse effects, including dysfunction of the liver and other organs. Liver cytochrome P450 (CYP450) enzymes play an important role in the metabolism of antipsychotics, and metabolizer types ...
Source: Clinical Case Reports - May 4, 2024 Category: General Medicine Authors: Min Yang, Yudong Cao, Haishan Wu, Li Zhang Tags: CASE REPORT Source Type: research

Single coronary artery with aortic valve replacement followed by aortic root replacement due to endocarditis: A case report
Key Clinical MessageA woman with a single coronary artery underwent aortic valve replacement due to aortic stenosis. Two years later, she developed an aortic annular abscess around the right coronary cusp and non-coronary cusp. Significant adhesions to the right coronary artery (RCA) resulted from the abscess, making artery separation challenging, and raising concerns about potential future RCA stenosis. The patient subsequently underwent aortic root replacement and coronary artery bypass grafting. Utilizing a freestyle valve and a saphenous vein graft for the RCA. Following the procedure, the patient was discharged and ha...
Source: Clinical Case Reports - May 4, 2024 Category: General Medicine Authors: Makoto Taoka, Akira Sezai, Masanao Ohba, Yoshiki Kitazumi, Taisuke Hanamura, Yasuo Okumura, Masashi Tanaka Tags: CASE REPORT Source Type: research

Perianal tuberculosis presenting as a Fournier's gangrene
Surgical treatment of perianal tuberculosis presenting as a Fournier ’s Gangrene: surgical perineal debridement (A, B); vacuum therapy of the perineum—sponge with sorbact (C, D); clean perineum after vacuum therapy (E). Key Clinical MessageIn the setting of Fournier's gangrene, atypical clinical manifestations and complications in an immunocompetent patient warrant consideration of perineal tuberculosis as a potential underlying cause.AbstractTuberculosis cutis orificialis is a rare form of extrapulmonary tuberculosis that affects the perianal region. Fournier's gangrene is an aggressive necrotizing fasciitis that prim...
Source: Clinical Case Reports - May 3, 2024 Category: General Medicine Authors: Raquel Lalanda, Andreia Bar ão, Beatriz Draiblate, Ester Malcato, Hélder Matos, José Girão, Rosário Rosa, José Paulo Freire, Luís Miranda Tags: CASE REPORT Source Type: research

A rare case of non ‐lupus full house nephropathy in a transplanted kidney, case report
Key Clinical MessageNon-lupus full house nephropathy is a rare entity that is still poorly understood. It can complicate post-transplant kidneys and result in a de novo process. Treatment is difficult but can be possibly achieved with optimization of immune suppression.AbstractNon-lupus full house nephropathy is a rare entity with an unclear incidence. It describes the kidney biopsy findings of positive deposits for IgG, IgA, IgM, C3, and C1q on immunofluorescence in the absence of the classical diagnostic features of systemic lupus nephritis. This disease entity is becoming more recognized but further studies are still ne...
Source: Clinical Case Reports - May 3, 2024 Category: General Medicine Authors: Ahmad Samir Matarneh, Omar Salameh, Sundus Sardar, Amanda Karasinski, Theja Channapragada, Muhammad Abdulbasit, Erik Washburn, Nasrollah Ghahramani Tags: CASE REPORT Source Type: research

Clinical image: Cervicofacial rotation skin flap in PLWD patients
This article outlines a surgical protocol designed for people living with dementia (PLWD). It proposes that simultaneous resection and reconstruction of skin cancer can minimizes the need for initial care. The method outlined involves primary closure via a cervicofacial rotation flap technique and the use of monofilament resorbable sutures. (Source: Clinical Case Reports)
Source: Clinical Case Reports - May 3, 2024 Category: General Medicine Authors: C. Politis, V. Lenaerts, L. Evrard, F. Shall, D. Gorl é Tags: CASE IMAGE Source Type: research

Unusual painful pelvic masses: Extramedullary hematopoiesis with extramedullary multiple myeloma
Computed tomography-guided biopsy of the right iliac fossa mass showing extramedullary hematopoiesis with extramedullary multiple myeloma (A, B; yellow arrow: erythroid island; green arrow: myeloid cell; white arrow: megakaryocyte; black arrows: atypical plasma cells with prominent nucleoli; short black arrow: Dutcher body in an atypical plasma cell). CD61 (C) and CD138 (D) immunohistochemistry stains highlight megakaryocytes and plasma cells, respectively. Key Clinical MessageThe coexistence of extramedullary hematopoiesis and extramedullary multiple myeloma can occur and present as painful pelvic masses. In such a case, ...
Source: Clinical Case Reports - May 3, 2024 Category: General Medicine Authors: Jennifer Cai, Marian Varda, David Sin, Halline Overby, James J. Yeh Tags: CASE IMAGE Source Type: research

Unsuccessful laparoscopic resection of a large pelvic solitary fibrous tumor: A case report
We present a rare case of a female pelvic solitary fibrous tumor unsuccessfully resected using single-port laparoscopy, requiring conversion to laparotomy. Although the resection was successful, the surgical approach could have been improved. For large tumors, minimally invasive results are possible with flexible choices of equipment and incision position. (Source: Clinical Case Reports)
Source: Clinical Case Reports - May 2, 2024 Category: General Medicine Authors: Xuping Shao, Haomeng Zhang, Yanqiu Wang, Changzhong Li, Jipeng Wan, Yonghui Zou Tags: CASE REPORT Source Type: research

Pedicle ossification after fibular flap reconstruction of maxillary defects: A case report and literature review
Key Clinical MessageThe phenomenon of vessel pedicle ossification is a noteworthy aspect of the repair and reconstruction of maxillofacial defects. Imaging findings typically reveal high-density shadows within the vascular pedicle pathway, which may be managed through conservative observation or surgical intervention as deemed appropriate.AbstractVessel pedicle ossification is a relatively uncommon complication associated with the reconstruction of oral and maxillofacial tissue defects using free tissue flap repair. In this paper, we report a case of pedicle ossification and conduct a comprehensive review of previous liter...
Source: Clinical Case Reports - May 2, 2024 Category: General Medicine Authors: Bo Zou Tags: CASE REPORT Source Type: research

Arthrogryposis, renal dysfunction, cholestasis syndrome with a novel mutation in two siblings
Key Clinical MessageThis current case series adds to the spectrum of Arthrogryposis renal dysfunction cholestasis (ARC)-associated variants. Increased awareness and early genetic testing for ARC are suggested in cases with failure to thrive, renal tubular dysfunction, and rickets, even when the degree of cholestasis is mild. Prompt identification and intervention may improve the quality of life. (Source: Clinical Case Reports)
Source: Clinical Case Reports - May 2, 2024 Category: General Medicine Authors: Rahiya Rehman, Leslia Gonzalez, Kelsey Kolbe, Mohammed Khurram Faizan, William Brucker, Carolina Cerezo Tags: CASE REPORT Source Type: research

The dual orexin receptor antagonist suvorexant in alcohol use disorder and comorbid insomnia: A case report
Key Clinical MessageThis case suggests using dual orexin receptor antagonists to treat alcohol use disorder and comorbid sleep disorders may be effective, commencing treatment in withdrawal and continuing it to prevent relapse.AbstractEffective medications for the treatment of alcohol use disorder are limited. This is partially due to the heterogenous nature of the symptomatology associated with alcohol use disorder and the abundance of presenting comorbidities. One common, and often overlooked, symptom that occurs during withdrawal of alcohol use is sleep disruption. Here, we report a case study of a participant with como...
Source: Clinical Case Reports - May 2, 2024 Category: General Medicine Authors: Erin J. Campbell, Yvonne Bonomo, Lisa Collins, Amanda Norman, Helen O'Neill, Amanda Streitberg, Kate Galloway, Andrew Kyoong, Andrew Perkins, Adam Pastor, Andrew J. Lawrence Tags: CASE REPORT Source Type: research