Unusual painful pelvic masses: Extramedullary hematopoiesis with extramedullary multiple myeloma

Computed tomography-guided biopsy of the right iliac fossa mass showing extramedullary hematopoiesis with extramedullary multiple myeloma (A, B; yellow arrow: erythroid island; green arrow: myeloid cell; white arrow: megakaryocyte; black arrows: atypical plasma cells with prominent nucleoli; short black arrow: Dutcher body in an atypical plasma cell). CD61 (C) and CD138 (D) immunohistochemistry stains highlight megakaryocytes and plasma cells, respectively. Key Clinical MessageThe coexistence of extramedullary hematopoiesis and extramedullary multiple myeloma can occur and present as painful pelvic masses. In such a case, normal hematopoietic cells may outnumber clonal plasma cells, posing a diagnostic challenge.
Source: Clinical Case Reports - Category: General Medicine Authors: Tags: CASE IMAGE Source Type: research