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Drug: Tetracycline
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Total 6023 results found since Jan 2013.
Minocycline improves autism-related behaviors by modulating microglia polarization in a mouse model of autism
Int Immunopharmacol. 2023 Jul 11;122:110594. doi: 10.1016/j.intimp.2023.110594. Online ahead of print.ABSTRACTAutism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder with few pharmacological treatments. Minocycline, a tetracycline derivative that inhibits microglial activation, has been well-identified with anti-inflammatory properties and neuroprotective effects. A growing body of research suggests that ASD is associated with neuroinflammation, abnormal neurotransmitter levels, and neurogenesis. Thus, we hypothesized that minocycline could improve autism-related behaviors by inhibiting microglia acti...
Source: International Immunopharmacology - July 13, 2023 Category: Allergy & Immunology Authors: Yi Luo Keyi Lv Zhulin Du Dandan Zhang Mei Chen Jing Luo Lian Wang Tianyao Liu Hong Gong Xiaotang Fan Source Type: research
The performance and mechanism of tetracycline and ammonium removal by Pseudomonas sp. DX-21
Bioresour Technol. 2023 Jul 11:129484. doi: 10.1016/j.biortech.2023.129484. Online ahead of print.ABSTRACTTo remove ammonium and tetracycline (TC) from wastewater, a new strain, DX-21, was isolated and exhibited simultaneous removal ability. The performance of DX-21 in TC removal, its removal mechanism, and the potential toxicities of the degradation products were investigated with genomics, mass spectrometry, density functional theory calculations, quantitative structure-activity relationship analyses, and Escherichia coli exposure experiments. DX-21 exhibited removal of ammonium (9.64 mg·L-1·h-1) via assimilation, and ...
Source: Bioresource Technology - July 13, 2023 Category: Biotechnology Authors: Mengya Yang Yue Jiao Luoting Sun Jingwen Miao Xu Song Mingyue Yin Lilong Yan Nan Sun Source Type: research
First Identification of bla < sub > NDM-1 < /sub > Producing Escherichia coli ST 9499 Isolated from Musca domestica in the Urban Center of Rio de Janeiro, Brazil
Curr Microbiol. 2023 Jul 12;80(9):278. doi: 10.1007/s00284-023-03393-y.ABSTRACTThe present study presents phenotypic and molecular characterization of a multidrug-resistant strain of Escherichia coli (Lemef26), belonging to sequence type ST9499 carrying a blaNDM-1 carbapenem resistance gene. The bacterium was isolated from a specimen of Musca domestica, collected in proximity to a hospital in Rio de Janeiro City, Brazil. The strain was identified as E. coli by matrix-assisted laser desorption-ionization time of flight mass spectrometry (Maldi-TOF-MS) and via genotypic analysis (Whole-Genome Sequencing-WGS), followed by phy...
Source: Current Microbiology - July 12, 2023 Category: Microbiology Authors: Isabel N Carramaschi Margareth M de C Queiroz Fabio Faria da Mota Viviane Zahner Source Type: research
Boosting mineralized organic pollutants by using a sulfur-vacancy CdS photocatalyst
Chem Commun (Camb). 2023 Jul 11. doi: 10.1039/d3cc02563b. Online ahead of print.ABSTRACTPhotocatalytic mineralization of organic pollutions and simultaneously converting CO2 to CO (tetracycline → CO2 → CO) represents a fascinating way to solve the environmental and energy crisis. This work demonstrates the excellent mineralization and CO2 reduction performance of S-vacancy CdS and reveals the high efficiency of the carbon self-recycling two-in-one photocatalytic system.PMID:37431776 | DOI:10.1039/d3cc02563b
Source: Chemical Communications - July 11, 2023 Category: Chemistry Authors: Huijie Wang Yang Wan Shikang Yin Mengyang Xu Xiaoxue Zhao Xin Liu Xianghai Song Huiqin Wang Chen Zhu Pengwei Huo Source Type: research
Combining a tetracycline (Tet)-inducible gRNA system and CRISPRa for titratable and timely controlled enhancement of endogenous SHISA3 activation in human induced pluripotent stem cells (hiPSC)
Stem Cell Res. 2023 Jul 5;71:103163. doi: 10.1016/j.scr.2023.103163. Online ahead of print.ABSTRACTTowards increasing the possibility for temporal control of gene expression using CRISPR activation (a) systems, we generated homozygous human induced pluripotent stem cell (hiPSC) lines carrying a doxycycline (dox)-inducible guide(g)-RNA construct targeting the SHISA3 transciptional start site, as proof-of-principle, or a non targeting gRNA as a control. The dox-inducible gRNA cassette was inserted into the human ROSA26 locus in a line with dCas9VPR integrated at the AAVS1 locus (CRISPRa/Tet-iSHISA3). Pluripotency, genomic in...
Source: Cell Research - July 11, 2023 Category: Cytology Authors: Laura Priesmeier Eric Schoger Lukas Cyganek Laura Cecilia Zelaray án Source Type: research
Boosting mineralized organic pollutants by using a sulfur-vacancy CdS photocatalyst
Chem Commun (Camb). 2023 Jul 11. doi: 10.1039/d3cc02563b. Online ahead of print.ABSTRACTPhotocatalytic mineralization of organic pollutions and simultaneously converting CO2 to CO (tetracycline → CO2 → CO) represents a fascinating way to solve the environmental and energy crisis. This work demonstrates the excellent mineralization and CO2 reduction performance of S-vacancy CdS and reveals the high efficiency of the carbon self-recycling two-in-one photocatalytic system.PMID:37431776 | DOI:10.1039/d3cc02563b
Source: Chemical Communications - July 11, 2023 Category: Chemistry Authors: Huijie Wang Yang Wan Shikang Yin Mengyang Xu Xiaoxue Zhao Xin Liu Xianghai Song Huiqin Wang Chen Zhu Pengwei Huo Source Type: research
Simultaneous removal of antibiotics and antibiotic resistant genes using a CeO < sub > 2 < /sub > @CNT electrochemical membrane-NaClO system
In this study, a coupled treatment system was developed using a CeO2 modified carbon nanotube electrochemical membrane and NaClO (denoted as CeO2@CNT-NaClO) to treat simulated water samples containing antibiotics and antibiotic-resistant bacteria (ARB). As the mass ratio of CeO2 to CNT was 5:7 and the current density was 2.0 mA/cm2, the CeO2@CNT-NaClO system removed 99% of sulfamethoxazole, 4.6 log sul1 genes, and 4.7 log intI1 genes from the sulfonamide-resistance water samples, and removed 98% of tetracycline, 2.0 log tetA genes, and 2.6 log intI1 genes of the tetracycline-resistance water samples. The outstanding perfor...
Source: Chemosphere - July 10, 2023 Category: Chemistry Authors: Xiaoyu Ni Xuan Hou Defang Ma Qian Li Ling Li Baoyu Gao Yan Wang Source Type: research
Fast and bioluminescent detection of antibiotic contaminants by on-demand transcription of RNA scaffold arrays
Anal Chim Acta. 2023 Sep 8;1273:341538. doi: 10.1016/j.aca.2023.341538. Epub 2023 Jun 17.ABSTRACTCell-free biosensors have inspired low-cost and field-applicable methods to detect antibiotic contaminants. However, the satisfactory sensitivity of current cell-free biosensors is mostly achieved by sacrificing the rapidity, which prolongs turnaround time by hours. Additionally, the software-based result interpretation provides an obstacle for delivering these biosensors to untrained individuals. Here, we present a bioluminescence-based cell-free biosensor, termed enhanced Bioluminescence sensing of Ligand-Unleashed RNA Expres...
Source: Analytica Chimica Acta - July 9, 2023 Category: Chemistry Authors: Rui Zhang Yu Wang Haifeng Deng Shiwen Zhou Yunhua Wu Yong Li Source Type: research
A study on the performance of a novel adsorbent UiO-66 modified by a nickel on removing tetracycline in wastewater
Chemosphere. 2023 Jul 7:139399. doi: 10.1016/j.chemosphere.2023.139399. Online ahead of print.ABSTRACTIn the present study, Ni-UiO-66 was synthesized to improve the adsorption efficiency of tetracycline (TC) in wastewater treatment. To this end, nickel doping was performed in the preparation process of UiO-66. The synthesized Ni-UiO-66 was characterized by XRD, SEM and EDS, BET, FTIR, TGA, and XPS for obtaining the lattice structure, surface topography, specific surface area, surface functional groups, and thermostability. More specifically, Ni-UiO-66 has a removal efficiency and adsorption capacity of up to 90% and 120 mg...
Source: Chemosphere - July 9, 2023 Category: Chemistry Authors: Guizhen Li Yao Zhang Xinyu Hu Wei Tan Jiaxiong Li Daiyan Su Hongbin Wang Min Yang Source Type: research
Design and construction of a robust ternary Bi < sub > 5 < /sub > O < sub > 7 < /sub > I/Cd < sub > 0.5 < /sub > Zn < sub > 0.5 < /sub > S/CuO photocatalytic system for boosted photodegradation of antibiotics via dual-S-scheme mechanisms: Environmental factors and degradation intermediates
Environ Res. 2023 Jul 7:116554. doi: 10.1016/j.envres.2023.116554. Online ahead of print.ABSTRACTThe detection of efficacious and environment-friendly nanomaterials with prominent photocatalytic performance is crucial for the detoxification of antibiotics in wastewater. Herein, a dual-S-scheme Bi5O7I/Cd0.5Zn0.5S/CuO semiconductor was designed and fabricated via a simple approach to degrade tetracycline (TC) and other types of antibiotics under LED illumination. However, Cd0.5Zn0.5S and CuO nanoparticles were decorated on the surface of the Bi5O7I microsphere to create a dual-S-scheme system that stimulates visible-light ut...
Source: Environmental Research - July 9, 2023 Category: Environmental Health Authors: Zaid H Jabbar Bassim H Graimed Saad H Ammar Maye M Alsunbuli Sarah A Hamood Hayder Hamzah Najm Athraa G Taher Source Type: research
