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Vaccination: Hepatitis Vaccine
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Total 4921 results found since Jan 2013.
Progress Toward Hepatitis B Control and Elimination of Mother-to-Child Transmission of Hepatitis B Virus - World Health Organization African Region, 2016-2021
MMWR Morb Mortal Wkly Rep. 2023 Jul 21;72(29):782-787. doi: 10.15585/mmwr.mm7229a2.ABSTRACTChronic hepatitis B virus (HBV) infection is one of the leading causes of cirrhosis and liver cancer. In 2019, approximately 1.5 million persons newly acquired chronic HBV infection; among these, 990,000 (66%) were in the World Health Organization (WHO) African Region (AFR). Most chronic HBV infections are acquired through mother-to-child transmission (MTCT) or during early childhood, and approximately two thirds of these infections occur in AFR. In 2016, the World Health Assembly endorsed the goal of elimination of mother-to-child t...
Source: MMWR Morb Mortal Wkl... - July 20, 2023 Category: Epidemiology Authors: Hyacinte J Kabore Xi Li Mary M Alleman Casimir M Manzengo Mutale Mumba Joseph Biey Gilson Paluku Ado M Bwaka Benido Impouma Rania A Tohme Source Type: research
Timeliness in the uptake of hepatitis B birth dose among Indian children under age five: A population-based study
CONCLUSION: Results indicated a need for targeted interventions to improve the coverage and timeliness in the uptake of this critical vaccine dose in the country. These interventions could include strategies such as strengthening the healthcare system, improving awareness among parents and healthcare providers, addressing logistical challenges in vaccine delivery, and promoting community engagement and education on importance of timely vaccination.PMID:37468388 | DOI:10.1016/j.vaccine.2023.07.015
Source: Vaccine - July 19, 2023 Category: Allergy & Immunology Authors: Sumit Kumar Das Junaid Khan Source Type: research
Establishment of a robust rat hepatitis E virus fecal-oral infection model and validation for antiviral studies
Antiviral Res. 2023 Jul 12:105670. doi: 10.1016/j.antiviral.2023.105670. Online ahead of print.ABSTRACTThe hepatitis E virus (HEV) is a major cause of hepatitis, with an estimated 3.3 million symptomatic cases annually. There is no HEV-specific treatment besides the off-label use of ribavirin and a vaccine is only available in China and Pakistan. To aid the development of therapeutic and preventive strategies, there is a need for convenient HEV infection models in small laboratory animals. To this end, we make use of the rat hepatitis E virus. Human infections with this virus have been reported in recent years, making it a...
Source: Antiviral Research - July 14, 2023 Category: Virology Authors: Xin Zhang Niels Cremers Stijn Hendrickx Yannick Debing Tania Roskams Lotte Coelmont Johan Neyts Suzanne J F Kaptein Source Type: research
Inhibitors Targeting Hepatitis C Virus (HCV) Entry
Mini Rev Med Chem. 2023;23(11):1193-1221. doi: 10.2174/1389557522666220428115152.ABSTRACTInfections caused by the Hepatitis C virus (HCV) affect around 70 million people worldwide, leading to serious liver problems, such as fibrosis, steatosis, and cirrhosis, in addition to progressing to hepatocellular carcinoma and becoming globally the main cause of liver disease. Despite great therapeutic advances in obtaining pan-genotypic direct-acting antivirals (DAAs), around 5-10% of affected individuals are unable to eliminate the virus by their own immune system's activity. Still, there are no licensed vaccines so far. In this c...
Source: Mini Reviews in Medicinal Chemistry - July 10, 2023 Category: Chemistry Authors: Paulo Fernando da Silva Santos-J únior Jo ão Xavier de Araújo-Júnior Edeildo Ferreira da Silva-J únior Source Type: research
Recombinant < em > Fowl aviadenovirus E < /em > (FAdV-E) penton base vaccination fails to confer protection against inclusion body hepatitis (IBH) in chickens
Avian Pathol. 2023 Jul 7:1-6. doi: 10.1080/03079457.2023.2226085. Online ahead of print.ABSTRACTInclusion body hepatitis (IBH) is a metabolic disease affecting chickens, associated with different serotypes of fowl adenovirus (FAdV). Experimentally tested vaccines against IBH include several capsid-based subunit vaccines, but not the penton base protein. In the present study, specific pathogen-free chickens were vaccinated with recombinant penton base expressed from each of two different FAdV serotypes (FAdV-7 and FAdV-8b), followed by challenge with a virulent IBH-causing strain. No protection was observed with either vacc...
Source: Avian Pathology - July 7, 2023 Category: Pathology Authors: Carlotta De Luca Anna Schachner Michael Hess Source Type: research
Sexual (Risk) Behavior and Risk-Reduction Strategies of Home-Based Male Sex Workers Who Have Sex with Men (MSW-MSM) in The Netherlands: A Qualitative Study
This study aimed to gain an understanding of sexual (risk) behavior, factors influencing sexual (risk) behavior, and applied risk-reduction strategies of home-based MSW-MSM. For this qualitative study, semi-structured individual interviews were conducted with 20 home-based MSW-MSM in the Netherlands. The interviews' recordings were transcribed verbatim and thematically analyzed with Atlas.ti 8. Condom use was reported to be high during anal sex, but low during oral sex and mostly determined by STI risk perception, trust in clients, and sexual pleasure. Many experienced condom failure, while few knew what to do after condom...
Source: Archives of Sexual Behavior - July 7, 2023 Category: Psychiatry & Psychology Authors: Charlotte M M Peters Ymke J Evers Nicole H T M Dukers-Muijrers Christian J P A Hoebe Source Type: research
Recombinant < em > Fowl aviadenovirus E < /em > (FAdV-E) penton base vaccination fails to confer protection against inclusion body hepatitis (IBH) in chickens
Avian Pathol. 2023 Jul 7:1-6. doi: 10.1080/03079457.2023.2226085. Online ahead of print.ABSTRACTInclusion body hepatitis (IBH) is a metabolic disease affecting chickens, associated with different serotypes of fowl adenovirus (FAdV). Experimentally tested vaccines against IBH include several capsid-based subunit vaccines, but not the penton base protein. In the present study, specific pathogen-free chickens were vaccinated with recombinant penton base expressed from each of two different FAdV serotypes (FAdV-7 and FAdV-8b), followed by challenge with a virulent IBH-causing strain. No protection was observed with either vacc...
Source: Avian Pathology - July 7, 2023 Category: Pathology Authors: Carlotta De Luca Anna Schachner Michael Hess Source Type: research
