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Effects of polyvinylchloride microplastics on the toxicity of nanoparticles and antibiotics to aerobic granular sludge: Nitrogen removal, microbial community and resistance genes
Environ Res. 2023 Sep 14:117151. doi: 10.1016/j.envres.2023.117151. Online ahead of print.ABSTRACTCopper oxide nanoparticles (CuO NPs) and ciprofloxacin (CIP) have ecological risk to humans and ecosystems. Polyvinylchloride microplastics (PVC MPs), as a representative of microplastics, may often coexist with CuO NPs and CIP in wastewater treatment systems due to their widespread application. However, the co-impact of PVC MPs in wastewater systems contained with CuO NPs and CIP on nitrogen removal and ecological risk is not clear. In this work, PVC MPs co-impacts on the toxicity of CuO NPs and CIP to aerobic granular sludge...
Source: Environmental Research - September 16, 2023 Category: Environmental Health Authors: Yu-Qi Li Bai-Hang Zhao Yu-Qing Zhang Xin-Yue Zhang Xiao-Tang Chen Hai-Shan Yang Source Type: research

A suggested protocol for value assignment using isotope-dilution-LC-MS/MS in reference measurement procedures - exemplary application for ciprofloxacin in serum
CONCLUSION: A standardized, detailed procedure for the application of isotope dilution LC-MS/MS in reference measurement procedures can complement the ISO 15193 standard with respect to this particular analytical technique, which is now widely used in the context of metrological traceability in laboratory medicine.PMID:37709112 | DOI:10.1016/j.cca.2023.117556
Source: International Journal of Clinical Chemistry - September 14, 2023 Category: Chemistry Authors: Judith Sch äffler Katharina Habler Michael Vogeser Source Type: research

Bioaccessibility of polypropylene microfiber-associated tetracycline and ciprofloxacin in simulated human gastrointestinal fluids
This study investigated the mechanism and primary factor controlling the bioaccessibility of polypropylene (PP) microplastic fiber-associated tetracycline (TC) and ciprofloxacin (CIP) in simulated human gastrointestinal fluids. After mixing 0.1 g of PP microfiber with 10 mg/L of TC (or CIP) for 96 h and exposure to simulated human gastrointestinal fluids, the TC concentrations were 0.440, 0.678, and 1.840 mg/L and the CIP concentrations were 0.700, 1.367, and 3.281 mg/L CIP in the simulated human saliva, gastric, and intestinal fluids after incubation for 60 s, 4 h, and 8 h, respectively. This indicated that the antibiotic...
Source: Environment International - September 13, 2023 Category: Environmental Health Authors: Xiaowei Wu Xiaoli Zhao Xia Wang Rouzheng Chen Peng Liu Weigang Liang Junyu Wang Di Shi Shixiang Gao Source Type: research

Prevalence and Antimicrobial-Resistant Features of < em > Shigella < /em > Species in East Africa from 2015-2022: A Systematic Review and Meta-Analysis
CONCLUSION: The pooled estimate indicates high burden of Shigella infection in East Africa, as well as a high proportion of drug resistance pattern to tetracycline, ampicillin, chloramphenicol, and amoxicillin. Therefore, initiating and scale-up of performing drug susceptibility test for each shigellosis case need to be considered and strengthened.PMID:37692062 | PMC:PMC10492654 | DOI:10.1155/2023/8277976
Source: Interdisciplinary Perspectives on Infectious Diseases - September 11, 2023 Category: Infectious Diseases Authors: Basha Ayele Getenet Beyene Mekdelawit Alemayehu Aman Dekebo Zeleke Mekonnen Gashaw Nigussie Source Type: research

Prevalence of ciprofloxacin resistance and associated genetic determinants differed among Campylobacter isolated from human and poultry meat sources in Pennsylvania
Food Microbiol. 2023 Dec;116:104349. doi: 10.1016/j.fm.2023.104349. Epub 2023 Aug 3.ABSTRACTPoultry is the primary source of Campylobacter infections and severe campylobacteriosis cases are treated with macrolides and fluoroquinolones. However, these drugs are less effective against antimicrobial-resistant strains. Here, we investigated the prevalence of phenotypic antimicrobial resistance and associated resistance genetic determinants in Campylobacter isolates collected from human clinical (N = 123) and meat (N = 80) sources in Pennsylvania in 2017 and 2018. Our goal was to assess potential differences in the prevalence o...
Source: Food Microbiology - September 9, 2023 Category: Food Science Authors: Runan Yan Nkuchia M M'ikanatha Irving Nachamkin Lauren K Hudson Thomas G Denes Jasna Kovac Source Type: research

Emerging threat of antimicrobial resistance in Neisseria gonorrhoeae: pathogenesis, treatment challenges, and potential for vaccine development
Arch Microbiol. 2023 Sep 9;205(10):330. doi: 10.1007/s00203-023-03663-0.ABSTRACTThe continuous rise of antimicrobial resistance (AMR) is a serious concern as it endangers the effectiveness of healthcare interventions that rely on antibiotics in the long run. The increasing resistance of Neisseria gonorrhoeae, the bacteria responsible for causing gonorrhea, to commonly used antimicrobial drugs, is a major concern. This has now become a critical global health crisis. In the coming years, there is a risk of a hidden epidemic caused by the emergence of gonococcal AMR. This will worsen the global situation. Infections caused by...
Source: Archives of Microbiology - September 9, 2023 Category: Microbiology Authors: Umairah Natasya Mohd Omeershffudin Suresh Kumar Source Type: research

Prevalence of ciprofloxacin resistance and associated genetic determinants differed among Campylobacter isolated from human and poultry meat sources in Pennsylvania
Food Microbiol. 2023 Dec;116:104349. doi: 10.1016/j.fm.2023.104349. Epub 2023 Aug 3.ABSTRACTPoultry is the primary source of Campylobacter infections and severe campylobacteriosis cases are treated with macrolides and fluoroquinolones. However, these drugs are less effective against antimicrobial-resistant strains. Here, we investigated the prevalence of phenotypic antimicrobial resistance and associated resistance genetic determinants in Campylobacter isolates collected from human clinical (N = 123) and meat (N = 80) sources in Pennsylvania in 2017 and 2018. Our goal was to assess potential differences in the prevalence o...
Source: Food Microbiology - September 9, 2023 Category: Food Science Authors: Runan Yan Nkuchia M M'ikanatha Irving Nachamkin Lauren K Hudson Thomas G Denes Jasna Kovac Source Type: research