Efficacy and Safety of Sarilumab in COVID-19: A Systematic Review
CONCLUSION: Sarilumab is a safe drug with good clinical outcomes in patients with COVID-19 and, hence, could be used as an alternative regimen for the treatment. Further prospective studies exploring the relations with baseline biomarkers of inflammation commonly measured such as C-reactive protein and IL-6 would be necessary for a correlation with the treatment.PMID:34721573 | PMC:PMC8556127 | DOI:10.1155/2021/8903435 (Source: Interdisciplinary Perspectives on Infectious Diseases)
Source: Interdisciplinary Perspectives on Infectious Diseases - November 1, 2021 Category: Infectious Diseases Authors: Rajan Chamlagain Sangam Shah Basanta Sharma Paudel Roman Dhital Bipin Kandel Source Type: research

The COVID-19 Prevalence among Children: Hypotheses for Low Infection Rate and Few Severe Forms among This Age Group in Sub-Saharan Africa
Interdiscip Perspect Infect Dis. 2021 Oct 12;2021:4258414. doi: 10.1155/2021/4258414. eCollection 2021.ABSTRACTDespite some cases of severe or critical manifestations of the coronavirus disease 2019 (COVID-19) described among children, the prevalence of this infection in the pediatric population is quite low worldwide, particularly in sub-Saharan Africa. Current data suggest indeed that, independent of the population considered overall, severe and critical cases of COVID-19 are rare among children. This observation prompted us to discuss the possible hypotheses which could explain the low prevalence of COVID-19 among child...
Source: Interdisciplinary Perspectives on Infectious Diseases - October 22, 2021 Category: Infectious Diseases Authors: Sylvain Raoul Simeni Njonnou Nadia Christelle Noumedem Anangmo Fernando Kemta Lekpa Diomede Noukeu Njinkui Dominique Enyama Christian Ngongang Ouankou Eric Vounsia Balti Esther Astrid Mbono Samba Eloumba Jean Roger Moulion Tapouh Simeon Pierre Choukem Source Type: research

Emergence of Highly Multidrug-Resistant Bacteria Isolated from Patients with Infections Admitted to Public Hospitals in Southwest Iran
CONCLUSIONS: This study highlights the emergence of MDR bacterial agents such as Acinetobacter species as a new threat in our region. However, a decrease in the rate of infection with Pseudomonas aeruginosa was noticeable.PMID:34422039 | PMC:PMC8378981 | DOI:10.1155/2021/5265379 (Source: Interdisciplinary Perspectives on Infectious Diseases)
Source: Interdisciplinary Perspectives on Infectious Diseases - August 23, 2021 Category: Infectious Diseases Authors: Sepide Namdari Ali Farhadi Aida Khademalhoseini Abbas Behzad-Behbahani Afsaneh Moaddeb Source Type: research