Filtered By:
Specialty: Chemistry
Therapy: Stem Cell Therapy
This page shows you your search results in order of date.
Order by Relevance | Date
Total 587 results found since Jan 2013.
Clinical analysis of bacterial infection characteristics in lymphoma patients with high-dose chemotherapy combined with autologous hematopoietic stem cell transplantation-a single-centered retrospective study
CONCLUSION: High-dose chemotherapy combined with autologous hematopoietic stem cell transplantation (HDT/AHSCT) is used to treat lymphoma. Although AHSCT has made considerable strides and become safer, HDT-AHSCT infection continues to be a leading cause of morbidity and mortality associated with transplantation.PMID:37718527 | DOI:10.2174/1386207326666230915115056
Source: Combinatorial Chemistry and High Throughput Screening - September 18, 2023 Category: Chemistry Authors: Dan-Hui Sun Di Mei Xiao-Qin Yaoz Yi-Hui Rong Gui-Qiang Wang Source Type: research
Scalable mesenchymal stem cell enrichment from bone marrow aspirate using deterministic lateral displacement (DLD) microfluidic sorting
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Nicholas Tan Kwan Zen, Kerwin Kwek Zeming, Kim Leng Teo, Mavis Loberas, Jialing Lee, Chin Ren Goh, Da Hou Yang, Steve Oh, James Hui Hoi Po, Simon M. Cool, Han Wei Hou, Jongyoon Han MSCs are enriched twice more efficiently with 10-fold shorten processing time from undiluted human bone marrow aspirate. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Lab Chip latest articles - September 13, 2023 Category: Chemistry Authors: Nicholas Tan Kwan Zen Source Type: research
Scalable Mesenchymal Stem Cells Enrichment from Bone Marrow Aspirate using Deterministic Lateral Displacement (DLD) Microfluidics Sorting
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Kwan Zen Nicholas Tan, Kerwin Zeming Kwek, Teo Kim Leng, Mavis Loberas, Jialing Lee, Chin Ren Goh, Da Hou Yang, Steve Oh, James Hui, Simon McKenzie Cool, Han Wei Hou, Jongyoon Han The growing interest in regenerative medicine has opened new avenues for novel cell therapies using stem cells. Bone Marrow Aspirate (BMA) is an important source of stromal mesenchymal stem cells... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Lab Chip latest articles - September 6, 2023 Category: Chemistry Authors: Kwan Zen Nicholas Tan Source Type: research
Reflow-molded deep concave microwell arrays for robust and large-scale production of embryoid bodies
Lab Chip, 2023, Accepted Manuscript DOI: 10.1039/D3LC00504F, PaperXue Han, Qi Zhang, Hui He, Qiang Zhao, Gang Li Embryonic stem cells (ESCs)-derived aggregates, called embryoid bodies (EBs), are powerful in vitro models used to study human development and disease. However, the cost-effective and large-scale production of homogeneous EBs... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Lab Chip latest articles - September 1, 2023 Category: Chemistry Authors: Xue Han Source Type: research
Discovery of N-(2-oxoethyl) sulfanilamide-derived inhibitors of KAT6A (MOZ) against leukemia by an isostere strategy
In conclusion, 6j shows excellent potential as a promising anti-leukemia drug candidate.PMID:37651878 | DOI:10.1016/j.ejmech.2023.115770
Source: European Journal of Medicinal Chemistry - August 31, 2023 Category: Chemistry Authors: Yongtao Duan Yabiao Zhao Zhenzhen Li Zhenling Liu Mingzhu Wang Xuan Wang Moran Sun Chuanjun Song Yongfang Yao Source Type: research
Identifying a Novel Eight-NK Cell-related Gene Signature for Ovarian Cancer Prognosis Prediction
CONCLUSION: The present study identified a RiskScore signature, which could stratify patients with different infiltration levels, immunotherapy, and chemotherapy drugs. Our study provided a basis for precisely evaluating OVC therapy and prognosis.PMID:37650393 | DOI:10.2174/0929867331666230831101847
Source: Current Medicinal Chemistry - August 31, 2023 Category: Chemistry Authors: Nan Li Kai Yu Delun Huang Hui Zhou Dingyuan Zeng Source Type: research
Inhibiting sorting nexin 10 promotes mucosal healing through SREBP2-mediated stemness restoration of intestinal stem cells
Sci Adv. 2023 Sep;9(35):eadh5016. doi: 10.1126/sciadv.adh5016. Epub 2023 Aug 30.ABSTRACTIntestinal stem cell (ISC) is a promising therapeutic target for inflammatory bowel disease. Cholesterol availability is critical for ISC stemness. Low plasma cholesterol is a typical feature of Crohn's disease (CD); however, its impact on mucosal healing remains unclear. Here, we identified an essential role of sorting nexin 10 (SNX10) in maintaining the stemness of ISCs. SNX10 expression in intestinal tissues positively correlates with the severity of human CD and mouse colitis. Conditional SNX10 knockout in intestinal epithelial cell...
Source: Anal Sci - August 30, 2023 Category: Chemistry Authors: Weilian Bao Yan You Jiahui Ni Hui Hou Jiaren Lyu Guize Feng Yirui Wang Keyuan You Sulin Zhang Lijie Zhang Xinyue Cao Xu Wang Haidong Li Hong Li Jiake Xu Chenying Liu Xiaomin Luo Peng Du Daofeng Chen Xiaoyan Shen Source Type: research
Coordinated Axial Ligand and d- π Conjugated Network Makes the Difference: Engineered 2D Mn-Based Antioxidase Mimic for Enhancing Stem Cell Protection
ChemMedChem. 2023 Aug 23:e202300325. doi: 10.1002/cmdc.202300325. Online ahead of print.ABSTRACTReactive oxygen species (ROS) refer to various partially reduced oxygen moieties that are naturally generated due to biochemical processes. Elevated formation of ROS leads to damage to biomolecules, resulting in oxidative stress and cell death. The increased level of ROS also affects therapeutics based on stem cell transplantation. Nanomaterials-based enzyme mimetics have attracted immense attention, but there are several challenges to be addressed in terms of selectivity, efficiency, and biocompatibility. This highlight focuses...
Source: ChemMedChem - August 23, 2023 Category: Chemistry Authors: Adarsh P Fatrekar Swathi Sreeram Amit Vernekar Source Type: research
Promoting neurite outgrowth and neural stem cell migration using aligned nanofibers decorated with protrusions and galectin-1 coating
Chem Commun (Camb). 2023 Aug 16. doi: 10.1039/d3cc02869k. Online ahead of print.ABSTRACTBiomaterials integrated with both topological cues and biological modifications are urgently needed in regenerative medicine. Here, aligned nanofibrous scaffolds decorated with nanoscale SiO2 protrusions and galectin-1 coating are reported. Prospects in neurite outgrowth and neural stem cell migration are discussed for suitable use in neural tissue engineering.PMID:37584646 | DOI:10.1039/d3cc02869k
Source: Chemical Communications - August 16, 2023 Category: Chemistry Authors: Yingnan Liu Xiaopei Zhang Yawen Wang Mingxia Guo Junyue Sheng Yuanfei Wang Tong Wu Source Type: research
Neotricitrinols A-C, unprecedented citrinin trimers with anti-osteoporosis activity from the deep-sea-derived Penicillium citrinum W23
Bioorg Chem. 2023 Jul 25;139:106756. doi: 10.1016/j.bioorg.2023.106756. Online ahead of print.ABSTRACTMarine fungi are prolific source for the discovery of structurally diverse and bioactive molecules. In our search for new anti-osteoporosis compounds from deep-sea-derived fungi, we prioritized a fungus whose extract exhibited moderate activity and rich chemical diversity. The investigation of this strain afforded a class of citrinins, including three new citrinin trimers, neotricitrinols A-C (1-3), and three known dimeric/monomeric precursors (4-6). Neotricitrinols A-C (1-3) feature a unique octacyclic carbon scaffold amo...
Source: Bioorganic Chemistry - August 6, 2023 Category: Chemistry Authors: Zhi-Hui He Chun-Lan Xie Taizong Wu Yong Zhang Zheng-Biao Zou Ming-Min Xie Lin Xu Robert J Capon Ren Xu Xian-Wen Yang Source Type: research
Promoting Neurite Outgrowth and Neural Stem Cell Migration using Aligned Nanofibers Decorated with Protrusions and Galectin-1 Coating
Chem. Commun., 2023, Accepted Manuscript DOI: 10.1039/D3CC02869K, CommunicationYingnan Liu, Xiaopei Zhang, Yawen Wang, Mingxia Guo, Junyue Sheng, Yuanfei Wang, Tong Wu Biomaterials integrated with both topological cues and biological modifications are urgently needed in regenerative medicine. Here, aligned nanofibrous scaffolds decorated with nanoscale SiO2 protrusions and galectin-1 coating are reported. Prospects... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - August 4, 2023 Category: Chemistry Authors: Yingnan Liu Source Type: research
