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Procedure: Liver Transplant

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Total 21872 results found since Jan 2013.

Where did platelets go in 2012? A survey of platelet transfusion practice in the North of England
ConclusionThe commonest indication for platelet use, where reinforcement of guidelines will be productive, is prophylaxis in haematological disease. Use of platelets in cardiac surgery is also worthy of close scrutiny.
Source: Transfusion Medicine - June 23, 2014 Category: Hematology Authors: A. Charlton, J. Wallis, J. Robertson, D. Watson, A. Iqbal, H. Tinegate Tags: TRANSFUSION PRACTICE Source Type: research

Acute liver failure
(ALF) is a rare condition, associated with high mortality and high healthcare cost. Common causes of acute liver injury leading to ALF are viral infection or specific drugs, with significant geographic variation in epidemiology. The most frequent cause of ALF in the UK is paracetamol (acetaminophen) toxicity. Advances in the critical care management of ALF, as well as surgical techniques and organ selection for transplantation, have improved outcomes for patients with ALF over recent decades.
Source: Medicine - September 24, 2015 Category: Internal Medicine Authors: Stewart Macdonald, Gautam Mehta, Rajiv Jalan Tags: Management problems in liver disease Source Type: research

Association of Postoperative Hypoalbuminemia With Acute Kidney Injury Following Liver Transplantation
No abstract available
Source: Critical Care Medicine - December 18, 2015 Category: Emergency Medicine Tags: Online Letters to the Editor Source Type: research

Hepatic Compartment Syndrome Following Percutaneous Cholecystostomy: A Case Report
Conclusions: Hepatic compartment syndrome must be suspected when acute liver failure occurs in patients with subcapsular hematoma. Only early management may avoid a fatal outcome or the need for an emergency liver transplantation.
Source: Critical Care Medicine - February 24, 2016 Category: Emergency Medicine Tags: Online Case Report Source Type: research

Is size the only determinant of delayed abdominal closure in pediatric liver transplant?
In conclusion, ALF was the main determinant of delayed abdominal closure rather than GRWR. The optimal time for delayed closure is within 6 weeks. The use of delayed abdominal closure does not adversely affect graft/child survival. This article is protected by copyright. All rights reserved.
Source: Liver Transplantation - December 26, 2016 Category: Transplant Surgery Authors: Shirin Elizabeth Khorsandi, Arthur William Raven Day, Miriam Cortes, Akash Deep, Anil Dhawan, Hector Vilca ‐Melendez, Nigel Heaton Tags: Original Article Source Type: research

Critically ill children can still undergo liver transplantation and survive
(American College of Surgeons) Advancements in critical care make it possible for even the sickest children to successfully undergo liver transplantation. According to a new study published online as an 'article in press' in the Journal of the American College of Surgeons (JACS), children who are sick enough to require mechanical ventilation or dialysis before transplantation achieve the same survival benefit as children who are stable prior to the surgical procedure.
Source: EurekAlert! - Medicine and Health - February 7, 2017 Category: Global & Universal Source Type: news

After the American Health Care Act
BY JOHN IRVINE We asked THCB’s editors and bloggers for their reactions to Friday’s news. Here are their reactions. DANIEL STONE, MD The late UCLA Professor Richard Brown, once commented that the Clinton healthcare initiative failed because the status quo was everyone’s second choice. Some of that logic applies to today’s failure to vote on the AHCA. Additionally, no one ever lost money betting against the rollback of an established entitlement program. The Republicans opponents of the ACA have not yet faced the fact that the reason coverage is so expensive is because the care is so expensive. You can’t ...
Source: The Health Care Blog - March 26, 2017 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized John Irvine Source Type: blogs

Pediatric Liver Transplantation
This article reviews updates and new development in pediatric liver transplan tation.
Source: Pediatric Clinics of North America - May 12, 2017 Category: Pediatrics Authors: Nidhi Rawal, Nada Yazigi Source Type: research

Long ‐term outcomes of de novo autoimmune hepatitis in pediatric liver transplant recipients
Abstract The long‐term course and outcome of DAIH is unknown. A retrospective multicenter study assessing associations and long‐term consequences of DAIH developing in a transplanted allograft is presented. Children with DAIH were followed from diagnosis until death, re‐LT, or transfer of care and for a minimum of 1 year. A total of 31 patients of 1833 (1.7%) LT were identified; 29 followed for a median of 7.1 years (range, 1.6‐15); 52% had no rejection preceding diagnosis of DAIH. Transaminases fell following treatment with steroids and antimetabolites (ALT 108 vs 39 U/L (P=.002); AST 112 vs 52 U/L (P=.003); GGT...
Source: Pediatric Transplantation - May 29, 2017 Category: Transplant Surgery Authors: Udeme D. Ekong, Patrick McKiernan, Mercedes Martinez, Steven Lobritto, Deirdre Kelly, Vicky L. Ng, Estella M. Alonso, Yaron Avitzur Tags: ORIGINAL ARTICLE Source Type: research

Incidence and predictors of massive bleeding in children undergoing liver transplantation: A single ‐center retrospective analysis
ConclusionsPediatric liver transplantation is associated with substantial blood loss and a significant blood product transfusion burden. A 43% incidence of massive bleeding is reported. Further efforts are needed to improve bleeding management in this high‐risk population.
Source: Pediatric Anesthesia - May 30, 2017 Category: Anesthesiology Authors: Benjamin Kloesel, Pete G. Kovatsis, David Faraoni, Vanessa Young, Heung Bae Kim, Khashayar Vakili, Susan M. Goobie Tags: RESEARCH REPORT Source Type: research

Pediatric liver transplantation
Considerable strides have been made over the last several decades towards improving outcomes in pediatric liver transplantation. Refinements in surgical technique has allowed for the use of living donor and deceased donor split-liver grafts, thus expanding the pool of available organs and reducing waitlist mortality. The use of a multidisciplinary team continues to be paramount in the care of the transplant recipient. With improvements in overall graft and survival, indications for liver transplantation have also broadened.
Source: Seminars in Pediatric Surgery - July 26, 2017 Category: Pediatrics Authors: Alex G. Cuenca, Heung Bae Kim, Khashayar Vakili Tags: 26/4 July/Aug - Transplantation issue Source Type: research

Molecular Adsorbent Recirculating System Can Reduce Short-Term Mortality Among Patients With Acute-on-Chronic Liver Failure—A Retrospective Analysis*
Conclusions: Molecular adsorbent recirculating system treatment was associated with an improved short-term survival of patients with acute-on-chronic liver failure and multiple organ failure. Among these high-risk patients, molecular adsorbent recirculating system treatment might bridge to liver recovery or liver transplantation.
Source: Critical Care Medicine - September 16, 2017 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Impact of Race and Ethnicity on Outcomes for Children Waitlisted for Pediatric Liver Transplantation
ABSTRACTObjective:African Americans and other minorities are known to face barriers to health care influencing their access to organ transplantation but it is not known whether these barriers exist among pediatric liver transplant waitlist candidates. We sought to determine whether outcomes on the waitlist (ie, mortality, deceased donor liver transplantation [DDLT], and living-donor liver transplantation [LDLT]) varied by race/ethnicity.Methods:National registry data were studied to estimate the race/ethnicity-specific risk of waitlist mortality, DDLT and LDLT in children (
Source: Journal of Pediatric Gastroenterology and Nutrition - February 24, 2018 Category: Gastroenterology Tags: Original Articles: Hepatology Source Type: research

Correction and Control of Hyperammonemia in Acute Liver Failure: The Impact of Continuous Renal Replacement Timing, Intensity, and Duration
Objectives: Hyperammonemia is a key contributing factor for cerebral edema in acute liver failure. Continuous renal replacement therapy may help reduce ammonia levels. However, the optimal timing, mode, intensity, and duration of continuous renal replacement therapy in this setting are unknown. We aimed to study continuous renal replacement therapy use in acute liver failure patients and to assess its impact on hyperammonemia. Design: Retrospective observational study. Setting: ICU within a specialized liver transplant hospital. Patients: Fifty-four patients with acute liver failure. Interventions: Data were ...
Source: Critical Care Medicine - January 16, 2020 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

DISIDA scans for the detection of biliary leaks following pediatric liver transplantation
Conclusions: DISIDA scans are useful in detecting biliary leaks following liver transplant in children. Inspection of the dynamic imaging during the first 60 minutes of a DISIDA scan to detect free tracer pooling adjacent to the grafted liver or tracer passing through in-situ surgical drains are important diagnostic features of bile leaks. Low flow rate biliary leaks may not be evident in the first 60 minutes and require further delayed imaging. We suggest that for maximal diagnostic accuracy a three phase imaging protocol is used consisting of (1) initial anterior dynamic planar imaging with surgical drains on free draina...
Source: Journal of Nuclear Medicine - May 14, 2020 Category: Nuclear Medicine Authors: London, K., Hettige, S., Thomas, G. Tags: Pediatrics Source Type: research