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Total 80128 results found since Jan 2013.
Concepts require flexible grounding
Brain Lang. 2023 Sep 13;245:105322. doi: 10.1016/j.bandl.2023.105322. Online ahead of print.ABSTRACTResearch on semantic memory has a problem. On the one hand, a robust body of evidence implicates sensorimotor regions in conceptual processing. On the other hand, a different body of evidence implicates a modality independent semantic system. The standard solution to this tension is to posit a hub-and-spoke system with modality independent hubs and modality specific spokes. In this paper, I argue in support of an alternative view of grounding which remains committed to neural reenactment but emphasizes the multimodal and mul...
Source: Brain and Language - September 15, 2023 Category: Neurology Authors: Guy Dove Source Type: research
Neurological presentation of profound hypothyroidism
Pract Neurol. 2023 Sep 15:pn-2023-003859. doi: 10.1136/pn-2023-003859. Online ahead of print.NO ABSTRACTPMID:37714702 | DOI:10.1136/pn-2023-003859
Source: Practical Neurology - September 15, 2023 Category: Neurology Authors: Christopher Paisey Gurjit Chohan Source Type: research
Concepts require flexible grounding
Brain Lang. 2023 Sep 13;245:105322. doi: 10.1016/j.bandl.2023.105322. Online ahead of print.ABSTRACTResearch on semantic memory has a problem. On the one hand, a robust body of evidence implicates sensorimotor regions in conceptual processing. On the other hand, a different body of evidence implicates a modality independent semantic system. The standard solution to this tension is to posit a hub-and-spoke system with modality independent hubs and modality specific spokes. In this paper, I argue in support of an alternative view of grounding which remains committed to neural reenactment but emphasizes the multimodal and mul...
Source: Brain and Language - September 15, 2023 Category: Neurology Authors: Guy Dove Source Type: research
Rhein attenuates cerebral ischemia-reperfusion injury via inhibition of ferroptosis through NRF2/SLC7A11/GPX4 pathway
CONCLUSION: Rhein attenuates cerebral I/R injury by inhibiting ferroptosis via the NRF2/SLC7A11/GPX4 axis, highlighting its potential as a therapeutic agent for ischemic stroke.PMID:37714424 | DOI:10.1016/j.expneurol.2023.114541
Source: Experimental Neurology - September 15, 2023 Category: Neurology Authors: Hua Liu Tian-Ai Zhang Wen-Yue Zhang Si-Rui Huang Yue Hu Jia Sun Source Type: research
Concepts require flexible grounding
Brain Lang. 2023 Sep 13;245:105322. doi: 10.1016/j.bandl.2023.105322. Online ahead of print.ABSTRACTResearch on semantic memory has a problem. On the one hand, a robust body of evidence implicates sensorimotor regions in conceptual processing. On the other hand, a different body of evidence implicates a modality independent semantic system. The standard solution to this tension is to posit a hub-and-spoke system with modality independent hubs and modality specific spokes. In this paper, I argue in support of an alternative view of grounding which remains committed to neural reenactment but emphasizes the multimodal and mul...
Source: Brain and Language - September 15, 2023 Category: Neurology Authors: Guy Dove Source Type: research
MicroRNA-125a-3p modulate amyloid β-protein through the MAPK pathway in Alzheimer's disease
CONCLUSION: Our study indicates that targeting miR-125a-3p may be an applicable therapy for AD in the future. However, more in vitro and in vivo studies with more samples are needed to confirm these results.PMID:37711111 | DOI:10.2174/1567205020666230913105811
Source: Current Alzheimer Research - September 15, 2023 Category: Neurology Authors: Xi-Chen Zhu Meng-Zhuo Zhu Jing Lu Qing-Yu Yao Jia-Wei Hu Wen-Jun Long Sha-Sha Ruan Wen-Zhuo Dai Rong Li Source Type: research
Early Detection of Dementia using Risk Classification in MCI: Outcomes of Shanghai Mild Cognitive Impairment Cohort Study
CONCLUSION: A simple risk classification using the rt. HV and neuropsychological test scores, including those from the ADAS-Cog-C and PACC, could be a practicable and efficient approach to identifying individuals at risk of all-cause dementia.PMID:37711110 | DOI:10.2174/1567205020666230914161034
Source: Current Alzheimer Research - September 15, 2023 Category: Neurology Authors: Bin Zhou Qianhua Zhao Shinsuke Kojima Ding Ding Satoshi Higashide Masanori Fukushima Zhen Hong Source Type: research
A rehabilitative approach beyond the acute stroke event: a scoping review about functional recovery perspectives in the chronic hemiplegic patient
ConclusionThe literature analyzed invites us to reflect respect to neurorehabilitation approach to the patient with chronic stroke sequelae often considered to have as its objective the maintenance of the present motor function and contain disability: instead, the review reports how, even in chronicity, the patient always reports margins of statistically and clinically significant improvement. The chronic stroke rehabilitation over 6 months has been proved effective in obtaining recovery in different settings.
Source: Frontiers in Neurology - September 15, 2023 Category: Neurology Source Type: research
Retinal microvasculature features in patients with migraine: a systematic review and meta-analysis
ConclusionMigraine patients are prone to retinal microcirculation disorders, such as decreased blood vessel density and increased avascular area in the fovea. This provides a theoretical basis for OCTA as a candidate for rapid, non-invasive diagnosis of migraine.
Source: Frontiers in Neurology - September 15, 2023 Category: Neurology Source Type: research
Success of conservative therapy for chronic subdural hematoma patients: a systematic review
ConclusionConservative therapy is reported to be successful in the majority of cSDH patients who have either no, or only mild symptoms. Hematoma volume, low hematoma density and absence of paresis could be factors associated with success. However, further research is warranted in order to establish factors consistently associated with a successful conservative therapy.OtherNo funding was acquired for this study. The study was not registered nor was a study protocol prepared.
Source: Frontiers in Neurology - September 15, 2023 Category: Neurology Source Type: research
When Does Intervention End and Surgery Begin? The Role of Interventional Pain Management in the Treatment of Spine Pathology
AbstractPurpose of ReviewRecent advances in the field of interventional pain management (IPM) involve minimally invasive procedures such as percutaneous lumbar decompression, interspinous spacer placement, interspinous-interlaminar fusion and sacroiliac joint fusion. These developments have received pushback from surgical professional societies, who state spinal instrumentation and arthrodesis should only be performed by spine surgeons. The purpose of this review is to evaluate the validity of this claim. A literature search was conducted on Google Scholar and PubMed databases. Articles were included which examined IPM in ...
Source: Current Pain and Headache Reports - September 15, 2023 Category: Neurology Source Type: research
Lumateperone Monotherapy for Treatment-Resistant OCD in an Adolescent
CNS Spectr. 2023 Sep 14:1-6. doi: 10.1017/S1092852923002468. Online ahead of print.NO ABSTRACTPMID:37706369 | DOI:10.1017/S1092852923002468
Source: CNS Spectrums - September 14, 2023 Category: Neurology Authors: Ahmed Naguy Saxby Pridmore Mohamed Y Abuzeid Dalal Elsori Bibi Alamiri Source Type: research
Artificial intelligence is set to transform mental health services
CNS Spectr. 2023 Sep 14:1-7. doi: 10.1017/S1092852923002456. Online ahead of print.NO ABSTRACTPMID:37706366 | DOI:10.1017/S1092852923002456
Source: CNS Spectrums - September 14, 2023 Category: Neurology Authors: Seithikurippu R Pandi-Perumal Meera Narasimhan Mary V Seeman Haitham Jahrami Source Type: research
Response to 'Neurologists should retain diagnostic and therapeutic management of migraines'
Neurol Neurochir Pol. 2023 Sep 14. doi: 10.5603/pjnns.97421. Online ahead of print.NO ABSTRACTPMID:37706669 | DOI:10.5603/pjnns.97421
Source: Neurologia i Neurochirurgia Polska - September 14, 2023 Category: Neurology Authors: Magdalena Boczarska-Jedynak Source Type: research
Differences in diffusion tensor imaging parameters of brain white matter tracts between patients with myotonic dystrophy type 1 and type 2 - a retrospective single-centre study
CONCLUSIONS: Our results indicate diffuse disintegration of white matter pathways in DM patients, especially in the DM1 group. The damage to all types of fibres (association, commissural, and projection) may explain the diversity of clinical symptoms, which were more severe in the DM1 group of patients than in the DM2 group.CLINICAL IMPLICATIONS: DTI in patients with DM may help us to understand the neural mechanisms underlying brain involvement during the disease. In future, it may help to identify biomarkers for disease progression and treatment response.PMID:37706668 | DOI:10.5603/pjnns.95587
Source: Neurologia i Neurochirurgia Polska - September 14, 2023 Category: Neurology Authors: Edyta Maj Tomasz Wolak Joanna de Meulder Katarzyna Janiszewska Miko łaj Wojtaszek Anna Kostera-Pruszczyk Marek Go łębiowski Anna Łusakowska Source Type: research
