Filtered By:
Vaccination: Veterinary Vaccinations

This page shows you your search results in order of relevance. This is page number 14.

Order by Relevance | Date

Total 8918 results found since Jan 2013.

Researchers uncover earliest events following HIV infection, before virus is detectable
(Beth Israel Deaconess Medical Center) New research in monkeys exposed to SIV, the animal equivalent of HIV, reveals what happens in the very earliest stages of infection, before virus is even detectable in the blood, which is a critical but difficult period to study in humans. The findings, published online today in the journal Cell, have important implications for vaccine development and other strategies to prevent infection.
Source: EurekAlert! - Medicine and Health - April 13, 2016 Category: Global & Universal Source Type: news

The Development of Small Animal Models for Zika Virus Vaccine Efficacy Testing and Pathological Assessment.
Abstract Zika virus (ZIKV) is a mosquito-borne flavivirus serologically grouped within the family Flaviviridae, which was initially isolated from a febrile sentinel monkey in the Zika Forest of Uganda in 1947. Subsequent genetic analyses have demonstrated the presence of two distinctive African and Asian viral genotypes. After years of being associated only with sporadic human illness, the first outbreak of ZIKV disease was reported in 2007, on the island of Yap in the Federated States of Micronesia (with 49 laboratory confirmed cases documented). In subsequent years, ZIKV was associated with outbreaks in French P...
Source: The American Journal of Tropical Medicine and Hygiene - May 1, 2016 Category: Tropical Medicine Authors: Brault AC, Bowen RA Tags: Am J Trop Med Hyg Source Type: research

Antibody Appears to Attack Cancer Cells, Leaving Other Cells Unscathed
Contact: Sarah Avery Phone: 919-660-1306 Email: sarah.avery@duke.edu https://www.dukehealth.org EMBARGOED FOR RELEASE until 12 p.m. noon (ET) on Thursday, May 5, 2016 DURHAM, N.C. -- A research team from Duke Health has developed an antibody from the body’s own immune system that preferentially attacks cancer cells. The antibody works by targeting a natural defense mechanism that cancer tumors exploit. Cells in the body essentially use a home security system that relies on certain proteins to protect the cell surface and keep it safe. These proteins help the cell avoid injury and even death from unwanted activation of th...
Source: DukeHealth.org: Duke Health Features - May 6, 2016 Category: Pediatrics Tags: Duke Medicine Source Type: news

An Important Step Forward Towards a Vaccine for Periodontal Disease
The various types of gum disease and periodontal conditions create insidious forms of damage, caused by the presence of unwanted but very persistent species of bacteria found in the mouth. Most people suffer inflammation of the gums to some degree, and this is due to the activities of bacteria such as Porphyromonas gingivalis. While it is true that there are a large number of ways to remove the bacterial species found in the mouth, the challenge is that they always return, and do so very quickly, often within days. This is obviously important from the point of view of the quality of your teeth over the long term, but argua...
Source: Fight Aging! - December 6, 2016 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

“We’ve learned to live with it” − A qualitative study of Australian horse owners’ attitudes, perceptions and practices in response to Hendra virus
Publication date: Available online 12 March 2017 Source:Preventive Veterinary Medicine Author(s): Anke K. Wiethoelter, Kate Sawford, Nicole Schembri, Melanie R. Taylor, Navneet K. Dhand, Barbara Moloney, Therese Wright, Nina Kung, Hume E. Field, Jenny-Ann L.M.L. Toribio Hendra virus causes sporadic zoonotic disease in Australia following spill over from flying foxes to horses and from horses to people. Prevention and risk mitigation strategies such as vaccination of horses or biosecurity and property management measures are widely publicised, but hinge on initiative and action taken by horse owners as they mediate managem...
Source: Preventive Veterinary Medicine - March 11, 2017 Category: Veterinary Research Source Type: research

“We’ve learned to live with it”—A qualitative study of Australian horse owners’ attitudes, perceptions and practices in response to Hendra virus
Publication date: 1 May 2017 Source:Preventive Veterinary Medicine, Volume 140 Author(s): Anke K. Wiethoelter, Kate Sawford, Nicole Schembri, Melanie R. Taylor, Navneet K. Dhand, Barbara Moloney, Therese Wright, Nina Kung, Hume E. Field, Jenny-Ann L.M.L. Toribio Hendra virus causes sporadic zoonotic disease in Australia following spill over from flying foxes to horses and from horses to people. Prevention and risk mitigation strategies such as vaccination of horses or biosecurity and property management measures are widely publicised, but hinge on initiative and action taken by horse owners as they mediate management, car...
Source: Preventive Veterinary Medicine - May 2, 2017 Category: Veterinary Research Source Type: research

Neutralizing the Threat: Pan-Ebolavirus Antibodies Close the Loop.
Abstract The glycoprotein (GP) of ebolaviruses participates in a critical membrane fusion process to establish infection of a cell and therefore, represents an important target of both vaccines and antivirals. The latest reports on pan-ebolavirus monoclonal antibodies in small animal models may offer promising outcomes and insight into how best to target the GP in vaccine and antiviral discovery. PMID: 28697885 [PubMed - as supplied by publisher]
Source: Trends in Molecular Medicine - July 8, 2017 Category: Molecular Biology Authors: Mire CE, Geisbert TW Tags: Trends Mol Med Source Type: research

Retrospective evaluation of 155 adult equids and 21 foals with tetanus from Western, Northern, and Central Europe (2000 –2014). Part 2: Prognostic assessment
ConclusionsPrognosis for equine tetanus is poor with similar outcome and prognostic factors in foals and adults. The prognostic assessment of cases with tetanus provides clinicians with new evidence‐based information related to patient management. Several prognostic indicators relate to the ability to eat or drink, and more severe clinical signs relate to poor outcome. Increasing intravenous dosages of TAT has no significant effect on outcome, but the positive trend identified may support a recommendation for high intravenous TAT dosages. Further evaluation is warranted.
Source: Journal of Veterinary Emergency and Critical Care - September 1, 2017 Category: Veterinary Research Authors: Gaby Galen, Joke Rijckaert, Tim Mair, Helene Amory, Lara Armengou, Barbora Bezdekova, Inge Durie, Rikke Findsh øj Delany, Nathalie Fouché, Laura Haley, Michael Hewetson, Rene den Hoven, Anna Kendall, Fernando Malalana, Jessika Muller Cavalleri, Tresemie Tags: Retrospective Study Source Type: research

Safety Analysis of Leishmania Vaccine Used in a Randomized Canine Vaccine/Immunotherapy Trial.
Abstract In Leishmania infantum-endemic countries, controlling infection within dogs, the domestic reservoir, is critical to public health. There is a need for safe vaccines that prevent canine progression with disease and transmission to others. Protective vaccination against Leishmania requires mounting a strong, inflammatory, Type 1 response. Three commercially available canine vaccines on the global veterinary market use saponin or inflammatory antigen components (Letifend) as a strong pro-inflammatory adjuvant. There is very little information detailing safety of saponin as an adjuvant in field trials. Safety...
Source: The American Journal of Tropical Medicine and Hygiene - March 5, 2018 Category: Tropical Medicine Authors: Toepp A, Larson M, Grinnage-Pulley T, Bennett C, Anderson M, Parrish M, Fowler H, Wilson G, Gharpure R, Cotter C, Petersen C Tags: Am J Trop Med Hyg Source Type: research

Gas ‑filled ultrasound microbubbles enhance the immunoactivity of the HSP70‑MAGEA1 fusion protein against MAGEA1‑expressing tumours.
Gas‑filled ultrasound microbubbles enhance the immunoactivity of the HSP70‑MAGEA1 fusion protein against MAGEA1‑expressing tumours. Mol Med Rep. 2018 May 09;: Authors: Gao X, Nan Y, Yuan Y, Gong X, Sun Y, Zhou H, Zong Y, Zhang L, Yu M Abstract Advanced malignant melanoma is characterized by rapid development, poor prognosis and insensitivity to chemoradiotherapy. Immunotherapy has become one of the primary clinical treatments for malignant melanomas. In recent decades, identifying specific tumour antigens and the enhanced immunoactivity of tumour vaccines has become critical for engineering succe...
Source: Molecular Medicine Reports - May 12, 2018 Category: Molecular Biology Tags: Mol Med Rep Source Type: research

Development and assessment of management practices in a flock-specific lameness control plan; a stepped-wedge trial on 44 English sheep flocks
In conclusion, separating lame sheep at treatment, culling sheep lame ≥2 occasions per year, and only using a footbath to treat outbreaks of interdigital dermatitis are flock managements that contribute to improved control of lameness in flocks with part-time farmers.
Source: Preventive Veterinary Medicine - July 1, 2018 Category: Veterinary Research Source Type: research

Development and assessment of management practices in a flock-specific lameness control plan: A stepped-wedge trial on 44 English sheep flocks
In conclusion, separating lame sheep at treatment, culling sheep lame ≥2 occasions per year, and only using a footbath to treat outbreaks of interdigital dermatitis are flock managements that contribute to improved control of lameness in flocks with part-time farmers.
Source: Preventive Veterinary Medicine - July 8, 2018 Category: Veterinary Research Source Type: research

Undoing Aging: Doug Ethell ' s Presentation on the Leucadia Therapeutics Approach to Treating Alzheimer ' s Disease
Doug Ethell has a clear and comparatively easily tested hypothesis on an important cause of Alzheimer's disease: that it results from the progressive failure of drainage of cerebrospinal fluid through one particularly crucial pathway in the skull. This traps ever greater levels of metabolic waste in the brain, such as amyloid-β, tau, and α-synuclein, and leads to the spectrum of well-known neurodegenerative diseases characterized by protein aggregates and resultant dysfunction and death of neurons. Dave Gobel of the Methuselah Foundation backed the first work on this hypothesis a few years back, and the result is ...
Source: Fight Aging! - August 1, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Examining Mitochondrial Dysfunction in Old T Cells
In older mice and humans, the immune system becomes dysfunctional. It is overactive, producing chronic inflammation that leads to harmful cellular behavior throughout the body, but at the same time it is much less capable when it comes to destroying pathogens and errant cells. In today's open access research, scientists investigate the incapacity of naive T cells in older mice. This population of T cells is necessary for a strong immune response, but their numbers decline due to the involution of the thymus. T cells begin life as thymocytes in the bone marrow, and then migrate to the thymus where they mature into T cells o...
Source: Fight Aging! - December 14, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs