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Exponential Medicine 2017 Day 1 & 2 Conference Overview: Virtual Reality, Transcriptomics, and an Exciting Announcement by the ACS
Welcome to Medgadget’s overview of this year’s Exponential Medicine (ExMed) conference by Singularity University (SU), which took place, for its fifth year in a row, in San Diego, CA at the Hotel Del Coronado last month. This year ExMed ...
Source: Medgadget - December 21, 2017 Category: Medical Devices Authors: Michael Batista Tags: Exclusive Medicine Source Type: blogs

Recent Advances and Trends in Pediatric Cardiac Imaging
AbstractCardiac imaging is central to today ’s pediatric cardiology practice not only to diagnose structural congenital defects and delineate cardiac and extracardiac anatomy but also for determining the hemodynamic impact of the structural defects and acquired pediatric diseases. Not so long ago, clinicians had to heavily rely on angiograp hy as the main cardiac imaging modality to visualize the heart. Particularly, the development of echocardiography in the 1970s and 1980s together with the development of magnetic resonance imaging (MRI) and computed tomography (CT) resulted in a non-invasive diagnostic revolution with...
Source: Current Treatment Options in Cardiovascular Medicine - February 21, 2018 Category: Cardiology Source Type: research

Evidence-based guideline of the European Association of Nuclear Medicine (EANM) on imaging infection in vascular grafts
ConclusionComputed tomography angiography (CTA) is the first-line imaging modality in suspected VGEI but nuclear medicine modalities are often needed to confirm or exclude the infection. Positron emission tomography/computed tomography (PET/CT) with 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) has very high negative predictive value but it should be performed preferably at least 4  months after surgery to avoid false positive results. Radiolabelled white blood cell (WBC) scintigraphy, given its high diagnostic accuracy, can be performed at any time after surgery.PreambleThe European Association of Nuclear Medicine (EANM) is...
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 4, 2022 Category: Nuclear Medicine Source Type: research

TCCD Fusion Imaging to Estimate Intracranial Pressure and Tissue Displacement with Large Hemispheric Infarction
ConclusionsFusion imaging is an easy method to access and acquire measurements for critical care patients and follow-up of tissue and vascular displacement after stroke. Fusion imaging may be a decisive support for indicating hemicraniectomy.
Source: Neurocritical Care - July 6, 2023 Category: Neurology Source Type: research

Prevalence and Risk Factors of Stress Cardiomyopathy After Convulsive Status Epilepticus in ICU Patients
Objective: Although stress cardiomyopathy has been described in association with epilepsy, its frequency in patients with convulsive status epilepticus remains unknown. Accordingly, we sought to determine the prevalence and risk factors of stress cardiomyopathy in patients admitted to the ICU for convulsive status epilepticus. Design: Prospective, descriptive, single-center study. Setting: Medical-surgical ICU of a teaching hospital. Patients: Thirty-two consecutive ventilated patients (21 men; age, 50 ± 18 yr; Simplified Acute Physiology Score II, 53 ± 15; Sequential Organ Failure Assessment, 6 ± 2) hospitalized in the...
Source: Critical Care Medicine - September 18, 2015 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Vertebral Artery Dissection Causing Stroke After Trampoline Use
Conclusions: Vertebral artery dissection is a relatively common cause of stroke in the pediatric age group. Trampoline use has been associated with significant risk of injury to the head and neck. Patients who are small and/or young are most at risk. In this case, minor trauma secondary to trampoline use could be a possible mechanism for vertebral artery dissection and subsequent strokes. The association in this case warrants careful consideration because trampoline use could pose a significant risk to pediatric users.
Source: Pediatric Emergency Care - November 1, 2015 Category: Emergency Medicine Tags: Illustrative Cases Source Type: research

Acute Thrombotic Occlusion of the Left Brachial Artery After Intra-Arterial Administration of Amiodarone
Conclusions: This is the first report of an acute thrombotic vessel occlusion leading to a compartment syndrome upon accidental intra-arterial injection of amiodarone in an emergency setting. In the hemodynamically unstable patient healthcare providers should be aware of arterial miscanulation and its consequences. Upon intra-arterial injection, a direct antithrombotic and vasodilative therapy should be administered via the initially misplaced arterial access, which may include a gpIIb/IIIa inhibitor.
Source: Critical Care Medicine - March 15, 2016 Category: Emergency Medicine Tags: Online Case Report Source Type: research

Prediction of Large Vessel Occlusions in Acute Stroke: National Institute of Health Stroke Scale Is Hard to Beat*
Objectives: Endovascular treatment for acute ischemic stroke with a large vessel occlusion was recently shown to be effective. We aimed to develop a score capable of predicting large vessel occlusion eligible for endovascular treatment in the early hospital management. Design: Retrospective, cohort study. Setting: Two tertiary, Swiss stroke centers. Patients: Consecutive acute ischemic stroke patients (1,645 patients; Acute STroke Registry and Analysis of Lausanne registry), who had CT angiography within 6 and 12 hours of symptom onset, were categorized according to the occlusion site. Demographic and clinical informati...
Source: Critical Care Medicine - May 17, 2016 Category: Emergency Medicine Tags: Online Clinical Investigations Source Type: research

Diaphragm Activation in Ventilated Patients Using a Novel Transvenous Phrenic Nerve Pacing Catheter
Objectives: Over 30% of critically ill patients on positive-pressure mechanical ventilation have difficulty weaning from the ventilator, many of whom acquire ventilator-induced diaphragm dysfunction. Temporary transvenous phrenic nerve pacing using a novel electrode-bearing catheter may provide a means to prevent diaphragm atrophy, to strengthen an atrophied diaphragm, and mitigate the harms of mechanical ventilation. We tested the initial safety, feasibility, and impact on ventilation of this novel approach. Design: First-in-Humans case series. Setting: Angiogram suite. Patients: Twenty-four sedated, mechanically venti...
Source: Critical Care Medicine - June 17, 2017 Category: Emergency Medicine Tags: Online Clinical Investigations Source Type: research

Out-of-hospital cardiac arrest: always coronary angiography?
Authors: Rognoni A, Cavallino C, Mennuni MG, Barbieri L, Rosso R, Rametta F, Nardi F, Lupi A, Bongo AS Abstract INTRODUCTION: Out-of-hospital cardiac arrest (OHCA) remains one of the principle challenges in the setting of critical care medicine and emergency cardiology. Areas covered: Long-term survival rates even after successful resuscitation are variable but increasing in the recent years; due to the improvement of base and advanced cardiac life support techniques an increasing number of resuscitated patients are admitted to the hospital. Some recent data have suggested that patients surviving to hospital discha...
Source: Expert Review of Cardiovascular Therapy - September 10, 2017 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research

Lack of Early Improvement Predicts Poor Outcome Following Acute Intracerebral Hemorrhage
Conclusions: Lack of clinical improvement at 24 hours robustly predicted poor outcome and showed good discrimination for individual patients who would do poorly. These findings are useful for prognostication and may also present as a potential early surrogate outcome for future intracerebral hemorrhage treatment trials.
Source: Critical Care Medicine - March 15, 2018 Category: Emergency Medicine Tags: Online Clinical Investigations Source Type: research

The Five-Year Clinical and Angiographic Follow-Up Outcomes of Intracoronary Transfusion of Circulation-Derived CD34+ Cells for Patients With End-Stage Diffuse Coronary Artery Disease Unsuitable for Coronary Intervention—Phase I Clinical Trial
This study investigated the clinical and angiographic long-term outcomes of intracoronary transfusion of circulation-derived CD34+ cells for patients with end-stage diffuse coronary artery disease unsuitable for coronary intervention. Design and Setting: A single-center prospective randomized double-blinded phase I clinical trial. Thirty-eight patients undergoing CD34+ cell therapy were allocated into groups 1 (1.0 × 107 cells/each vessel; n = 18) and 2 (3.0 × 107 cells/each vessel; n = 20). Patients: Those with end-stage diffuse coronary artery disease were unsuitable for percutaneous and surgical coronary...
Source: Critical Care Medicine - April 14, 2018 Category: Emergency Medicine Tags: Online Clinical Investigations Source Type: research

Development of massive pulmonary embolism during echocardiographic imaging: A case report
Rationale: Pulmonary embolism (PE) is a common diagnostic consideration for patients who present to the emergency department (ED) with chest pain, dyspnea, or both. In addition, PE has a very high mortality in patients who are hemodynamically unstable. An electrocardiography, bedside transthoracic echocardiogram, and computed tomography pulmonary angiogram are usually performed to confirm the diagnosis. Patient concerns: A 53-year-old man was admitted to the cardiology clinic with complaints of dyspnea, chest pain, and general weakness after walking. He had a history of hypertension and smoking. Diagnosis: During s...
Source: Medicine - April 1, 2018 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Presepsin and Inflammatory Markers Correlate With Occurrence and Severity of Nonocclusive Mesenteric Ischemia After Cardiovascular Surgery
Conclusions: Elevated postoperative plasma presepsin concentrations are an independent predictor of mild and severe nonocclusive mesenteric ischemia. The established inflammatory blood markers significantly correlate with the development and severity of nonocclusive mesenteric ischemia.
Source: Critical Care Medicine - May 17, 2018 Category: Emergency Medicine Tags: Online Clinical Investigations Source Type: research