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Total 6767 results found since Jan 2013.

Comparative Effectiveness of Lumbar Transforaminal Epidural Steroid Injections with Particulate Versus Nonparticulate Corticosteroids for Lumbar Radicular Pain due to Intervertebral Disc Herniation: A Prospective, Randomized, Double-Blind Trial.
CONCLUSIONS: Transforaminal epidural corticosteroid injections are an effective treatment for acute radicular pain due to disc herniation, and frequently only require 1 or 2 injections for symptomatic relief. Dexamethasone appears to possess reasonably similar effectiveness when compared with triamcinolone. However, the dexamethasone group received slightly more injections than the triamcinolone group to achieve the same outcomes. PMID: 24393129 [PubMed - as supplied by publisher]
Source: Pain Physician - January 2, 2014 Category: Anesthesiology Authors: Kennedy DJ, Plastaras C, Casey E, Visco CJ, Rittenberg JD, Conrad B, Sigler J, Dreyfuss P Tags: Pain Med Source Type: research

Prescribing Trends of Palliative Care Team's Use of Dexamethasone for Cancer-Related Pain.
Authors: Barghi K, Edmonds KP, Ajayi TA, Atayee RS Abstract Opioids are first-line therapy for cancer-related pain. In addition, corticosteroids are commonly utilized as adjuvant analgesics for pain and other symptoms in the oncology setting with limited supporting data. A retrospective analysis was conducted evaluating adult hospitalized patients receiving opioids who received once-daily dexamethasone on the recommendation of a specialty palliative care team during their hospitalization from January 1, 2015, to January 1, 2016. Primary end point was to describe prescribing patterns of dexamethasone in this patient...
Source: Journal of Pain and Palliative Care Pharmacotherapy - May 9, 2018 Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research

Early Treatment of Acute Complex Regional Pain Syndrome after Fracture or Injury with Prednisone: Why Is There a Failure to Treat? A Case Series.
Conclusion. Corticosteroids can be an effective treatment option for CRPS after fracture. PMID: 27445622 [PubMed - in process]
Source: Pain Research and Management - July 26, 2016 Category: Anesthesiology Authors: Winston P Tags: Pain Res Manag Source Type: research

Local Drug Infiltration Analgesia During Knee Surgery to Reduce Postoperative Pain in Rats
Conclusions: Our animal study suggests that clinical trials with LIA combinations of local anesthetic, nonsteroidal anti-inflammatory drug, and corticosteroid might be useful for reducing postoperative pain after knee surgery, with the nonsteroidal anti-inflammatory drug having the greatest effect. Perioperative physicians should consider delivering LIA earlier during the procedure as opposed to solely at the time of wound closure.
Source: Regional Anesthesia and Pain Medicine - April 21, 2016 Category: Anesthesiology Tags: Regional Anesthesia and Acute Pain: Original Articles Source Type: research

Prospective, Multicenter, Randomized, Crossover Clinical Trial Comparing the Safety and Effectiveness of Cooled Radiofrequency Ablation With Corticosteroid Injection in the Management of Knee Pain From Osteoarthritis
This study compared long-term clinical safety and effectiveness of cooled radiofrequency ablation (CRFA) with intra-articular steroid (IAS) injection in managing OA-related knee pain. Methods This is a prospective, multicenter, randomized trial with 151 subjects with chronic (≥6 months) knee pain that was unresponsive to conservative modalities. Knee pain (Numeric Rating Scale [NRS]), Oxford Knee Score, overall treatment effect (Global Perceived Effect), analgesic drug use, and adverse events were compared between CRFA and IAS cohorts at 1, 3, and 6 months after intervention. Results There were no differences in de...
Source: Regional Anesthesia and Pain Medicine - December 29, 2017 Category: Anesthesiology Tags: Chronic and Interventional Pain: Original Article Source Type: research

Comparing pain relief and functional improvement between methylprednisolone and dexamethasone lumbosacral transforaminal epidural steroid injections: a self-controlled study.
Conclusions: These findings support the use of non-particulate corticosteroids for lumbosacral TFESIs in the context of documented safety concerns with particulate corticosteroids. PMID: 32235020 [PubMed]
Source: Korean Journal of Pain - April 4, 2020 Category: Anesthesiology Tags: Korean J Pain Source Type: research

New Wrinkle for Old Drug It’s not just for smoothing laugh lines. Botulinum toxin may have the potential to ease OA pain.| Arthritis Today Magazine
Widely used by doctors to soften forehead wrinkles and reduce uncontrollably sweaty armpits, researchers now are exploring botulinum toxin as a potential therapy for osteoarthritis (OA) pain. Although botulinum toxin (Botox, Dysport, Myobloc) has been studied since the 1950s, recent studies on its use in osteoarthritis pain suggest it could be a new analgesic option for a group of patients that's been hard to treat. "The Botox story is very intriguing," says David Felson, MD, professor of medicine and epidemiology at Boston University. "It isn't just muscles. It can paralyze nerves. Just like celeb...
Source: Psychology of Pain - October 30, 2013 Category: Psychiatrists and Psychologists Source Type: blogs

If you have low back pain try these steps first
Low back pain, the scourge of mankind: it is the second leading cause of disability here in the United States, and the fourth worldwide. It’s also one of the top five medical problems for which people see doctors. Almost every day that I see patients, I see someone with back pain. It’s one of the top reasons for lost wages due to missed work, as well as for healthcare dollars spent, hence, a very expensive problem. Looking at two kinds of back pain Let’s talk about the most common forms of back pain: acute (which lasts less than four weeks) and subacute (which lasts four to 12 weeks). Most of these cases (approximate...
Source: Harvard Health Blog - April 3, 2017 Category: Consumer Health News Authors: Monique Tello, MD, MPH Tags: Back Pain Managing your health care Pain Management Source Type: blogs

Taming the pain of sciatica: For most people, time heals and less is more
Despite being a less common cause of low back pain, sciatica is still something I regularly see as a general internist. Primary care doctors can and should manage sciatica, because for most individuals the body can fix the problem. My job is to help manage the pain while the body does its job. When a person’s symptoms don’t improve, I discuss the role of surgery or an injection to speed things up. What is sciatica? Sciatica refers to pain caused by the sciatic nerve that carries messages from the brain down the spinal cord to the legs. The pain of sciatica typically radiates down one side from the lower back into the l...
Source: Harvard Health Blog - July 12, 2017 Category: Consumer Health News Authors: Steven J. Atlas, MD, MPH Tags: Back Pain Health Pain Management Source Type: blogs

Physical therapy as good as surgery and less risky for one type of lower back pain
One type of lower back pain, called lumbar spinal stenosis, is sometimes treated with surgery. But physical therapy works just as well, and comes with fewer unwanted complications — some of them life-threatening — than surgery, according to a study published yesterday in Annals of Internal Medicine. Stenosis means narrowing. In lumbar spinal stenosis, the space inside the lowest part of the spinal canal has narrowed. This puts pressure on the spinal cord and the nerves extending from the lumbar vertebrae, the five bones between the rib cage and the pelvis that make up the lower part of the spine. Spinal stenosis usuall...
Source: New Harvard Health Information - April 9, 2015 Category: Consumer Health News Authors: Howard LeWine, M.D. Tags: Back Pain Pain Management lower back pain lumbar spinal stenosis physical therapy Source Type: news

Beating osteoarthritis knee pain: Beyond special shoes
We have plenty of fairy tales about shoes that work magic in people’s lives: glass slippers that brought love to Cinderella, and sparkly red heels that gave Dorothy powers in MGM’s version of The Wizard of Oz. In real life, footwear magic is limited to “unloading” shoes that may help relieve knee pain from osteoarthritis. These unloading shoes have stiffer soles, and slightly tilted insoles that reposition the foot, intended to reduce (or unload) strain on the knee. But a study published online July 12, 2016, in Annals of Internal Medicine suggests that unloading shoes are no better than a good pair of walking shoe...
Source: New Harvard Health Information - August 1, 2016 Category: Consumer Health News Authors: Heidi Godman Tags: Exercise and Fitness Health Osteoarthritis Pain Management Source Type: news

Nonopioid Drugs in the Treatment of Cancer Pain REVIEW ARTICLES
The WHO analgesic ladder for the treatment of cancer pain provides a three-step sequential approach for analgesic administration based on pain severity that has global applicability. Nonopioids were recommended for mild pain, with the addition of mild opioids for moderate pain and strong opioids for severe pain. Here, we review the evidence for the use of nonopioid analgesic agents in patients with cancer and describe the mode of action of the main drug classes. Evidence supports the use of anti-inflammatory drugs such as acetaminophen/paracetamol and nonsteroidal anti-inflammatory drugs (NSAIDs) for mild cancer pain. Addi...
Source: Journal of Clinical Oncology - May 27, 2014 Category: Cancer & Oncology Authors: Vardy, Agar Tags: Pain Control, Pain Control REVIEW ARTICLES Source Type: research

The Pain Quality Response Profile of a Corticosteroid Injections and Heated Lidocaine/Tetracaine Patch in the Treatment of Shoulder Impingement Syndrome
This study presents pain quality data from a randomized open-label study comparing the effects of an injection of triamcinolone and up to twice daily application of a heated lidocaine/tetracaine (Trilexis) patch in individuals with SIS. Study participants completed a measure of pain quality at baseline and again on study days 14, 28, and 42 following initiation of 2 treatments for SIS. Baseline and posttreatment pain quality scores were graphed to provide a visual representation of treatment-associated changes. Analyses of variance were used to examine the differences between treatment conditions in changes in pain quality...
Source: The Clinical Journal of Pain - March 9, 2015 Category: Anesthesiology Tags: Original Articles Source Type: research

Efficacy of a Subacromial Corticosteroid Injection for Persistent Pain After Arthroscopic Rotator Cuff Repair
Conclusion: A subacromial corticosteroid injection can be considered as a useful and safe modality for the treatment of patients having severe persistent pain during the recovery phase after arthroscopic rotator cuff repair.
Source: The American Journal of Sports Medicine - August 31, 2016 Category: Sports Medicine Authors: Shin, S.-J., Do, N.-H., Lee, J., Ko, Y.-W. Tags: Tennis, Shoulder, rotator cuff, Anesthesia/pain management, Baseball/Softball, Golf Source Type: research