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Vaccination: Cancer Vaccines

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Total 7677 results found since Jan 2013.

Immune response to anti-SARS-CoV-2 prime-vaccination in patients with cancer: a systematic review and meta-analysis
CONCLUSION: This meta-analysis provides compelling evidence of humoral and adaptive immune responses against SARS-CoV-2 in patients with cancer, which last for at least 2 months following complete prime-vaccination.PMID:35867203 | PMC:PMC9304540 | DOI:10.1007/s00432-022-04185-w
Source: Clinical Genitourinary Cancer - July 22, 2022 Category: Cancer & Oncology Authors: Diogo Martins-Branco Guilherme Nader-Marta Ana Tecic Vuger Veronique Debien Lieveke Ameye Mariana Brand ão Kevin Punie Angela Loizidou Karen Willard-Gallo Chloe Spilleboudt Ahmad Awada Martine Piccart Evandro de Azambuja Source Type: research

Debulking hysterectomy followed by chemoradiotherapy versus chemoradiotherapy for FIGO stage (2019) IB3/II cervical cancer
CONCLUSIONS: There was no evidence for or against debulking hysterectomy followed by CCRT versus CCRT alone for FIGO (2019) stage IB3/II cervical cancer.PMID:36111784 | PMC:PMC9479467 | DOI:10.1002/14651858.CD012246.pub2
Source: Cochrane Database of Systematic Reviews - September 16, 2022 Category: General Medicine Authors: Manas Chakrabarti Andy Nordin Juneida Khodabocus Source Type: research

Meta-analysis and Critical Review: Association Between Radio-induced Lymphopenia and Overall Survival in Solid Cancers
CONCLUSIONS: RIL is a significant prognostic factor for mortality in virtually all solid cancers. Pooled-effect estimates indicate a significantly reduced risk of death in patients without RIL. Tailoring RT regimens to spare the immune system and updating dosimetric constraints for new organs at risk, such as major blood vessels, organs with rich blood supplies, bones, and all lymph node areas, may improve prognoses.PMID:36561078 | PMC:PMC9763695 | DOI:10.1016/j.adro.2022.101038
Source: Adv Data - December 23, 2022 Category: Epidemiology Authors: Yasmine El Houat Christophe Massard Veronique Quillien Renaud de Crevoisier Jo ël Castelli Source Type: research

Developments in targeted therapy & amp; immunotherapy-how non-small cell lung cancer management will change in the next decade: a narrative review
CONCLUSIONS: This review encompasses the latest updates in targeted therapy and immunotherapy in lung cancer management and discusses the future direction in the field.PMID:37675321 | PMC:PMC10477626 | DOI:10.21037/atm-22-4444
Source: Cancer Control - September 7, 2023 Category: Cancer & Oncology Authors: Molly S C Li Kevin K S Mok Tony S K Mok Source Type: research

Prevalence of hepatitis B infection in the Gambian population: A narrative review of recent developments
This study reviewed the recent trends in the epidemiological characteristics of HBV in the Gambia. The researchers conducted an online literature search for primary studies on HBV prevalence published in the past two decades from Jan 1992 to Feb 2022 inclusive on Google Scholar, PubMed, and Scopus. All retrieved studies were assessed for eligibility according to specific inclusion/exclusion criteria, data completeness, and methodological coherence. We found that HBV infection prevalence is above 8% in The Gambia. Moreover, HBV is the most common cause of hepatocellular carcinoma (HCC) in Gambia. Liver cirrhosis and HCC hav...
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Muhammed Camara Marcarious M Tantuoyir SeyedAhmad SeyedAlinaghi Fereshteh Ghiasvand Zahra Ahmadinejad Source Type: research

Some Authoritative Skepticism about the "Triumph" of Sovaldi to Add to Outrage about "Blood Money"
This report just appeared online in JAMA Internal Medicine [Ollendorf DA, Tice JA et al.  The comparative clinical effectiveness and value of simeprevir and sofosbuvir in chronic hepatitis C viral infection.  JAMA Inte Med 2014.  Link here.] The review found again that there were major limitations in the available data, and so much of it was based on a network meta-analysis and simulation studies,The review was limited to patients with genotype 1, 2, and 3 infections, which account for most HCV cases in the United States. At the time of the review, no head-to-head trials of the direct-acting antiviral d...
Source: Health Care Renewal - May 7, 2014 Category: Health Management Tags: evidence-based medicine Gilead health care prices manipulating clinical research pharmaceuticals Sovaldi Source Type: blogs

Dobbs Roundup Week of 16/6/2014 – 20/6/2014)
Dear Dobber,   Hope you’ve had a great week but not lost too much sleep watching the World Cup matches (fans check out this thread). Here’s an update for the weekend to tell you of what’s fresh in Dobbs. Feel free to click on the links if anything interests you. Picks of the week from the Forums MOH to restructure Medical Certificate System MOH plans to put in place a system to tackle fake MCs and medical absenteeism. Will it work? Prophylactic corticosteroids – any guidelines @mrnginbox had a question about prophylactic steroids for contrast MRI scans. Dobber radiologists answer. Dad puts sons through med sch...
Source: Malaysian Medical Resources - June 21, 2014 Category: Global & Universal Authors: palmdoc Tags: - Dobbs forum Source Type: blogs

Can Gingko and Turmeric Help Stop Ebola?
Summary There is no known pharmaceutical currently available that specifically treats Ebola disease. One treatment modality that should be considered is the use of herbal medicines, which have both centuries old anecdotal success as well as recent modern biochemical and formal research rationales for their use. Five areas of action that could be addressed by the herbal medicines as it relates to Ebola would be: VP24/immune system evasion GP protein/replicatio; herbal strategies effective against similar hemorrhagic disease beneficial modulation of patient immune and inflammatory response systems prophylactic use for heal...
Source: Inside Surgery - August 1, 2014 Category: Surgery Authors: Editor Tags: Infectious Disease ayurvedic baicalen cathepsin b dengue Ebola gingko herb Quercetin resveratrol rosemary sage st johns work turmeric Source Type: blogs

Antigen-specific active immunotherapy for ovarian cancer.
CONCLUSIONS: We conclude that despite promising immunological responses, no clinically effective antigen-specific active immunotherapy is yet available for ovarian cancer. Results should be interpreted cautiously as there was a significant lack of relevant information for the assessment of risk of bias in both RCTs and non-RCTs. PMID: 25229990 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - September 17, 2014 Category: Journals (General) Authors: Leffers N, Daemen T, Helfrich W, Boezen HM, Cohlen BJ, Melief CJ, Nijman HW Tags: Cochrane Database Syst Rev Source Type: research

Emerging Therapies for Glioblastoma
Conclusions and RelevanceGlioblastoma is an aggressive tumor with heterogeneous molecular features and complex host interactions, many of which are amenable to therapeutic intervention. Meaningful treatment advances will depend on identifying agents that target mechanistic vulnerabilities that are relevant to specific subgroups of patients; increasing patient enrollment into clinical trials is essential to accelerate the development of patient-tailored treatments.
Source: JAMA Neurology - November 1, 2014 Category: Neurology Source Type: research