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Total 3838 results found since Jan 2013.

Effect of Acacia catechu and alum hot sitzbath on post-operative pain in patients treated with herbal seton
ConclusionOn comparative analysis Acacia and Alum hot sitzbath was more effective in outcomes like pain, surgical satisfaction, burning sensation and discharge. There was no difference in the effect of both interventions with respect to outcome measures like constipation, itching and incontinence.ResumoJustificativaA dor pós-operatória é a principal consequência da técnica que utiliza seton de Kṣārasūtra no tratamento ayurvédico de fístula anal baixa. Os cirurgiões são impelidos a prescrever opiáceos e AINEs que possuem efeitos indesejáveis pronunciados. Medidas não farmacológicas como a balneoterapia são...
Source: Journal of Coloproctology - December 19, 2019 Category: Gastroenterology Source Type: research

Efficacy, safety, and cost-effectiveness analysis of adjuvant herbal medicine treatment, Palmijihwang-hwan, for chronic low back pain: a study protocol for randomized, controlled, assessor-blinded, multicenter clinical trial
This study is a randomized, assessor-blinded, multicenter, clinical trial with two parallel groups. Four Korean medicine hospitals will recruit 84 participants and randomly allocate them into the control or treatment group in a 1:1 ratio. The control group will receive acupuncture treatment at 11 local and 4 distal acupuncture points for 20  min twice a week for 6 weeks. The treatment group will receive the same acupuncture treatment as the control group and also take Palmijihwang-hwan for 6 weeks. The primary outcome will be the change in visual analog scale (VAS) score between baseline (visit 1) and completion of the i...
Source: Trials - December 26, 2019 Category: Research Source Type: clinical trials

A study on the effectiveness of pharmacopuncture for chronic neck pain: A protocol for a pragmatic randomized controlled trial
This study is a 2-armed, parallel, multi-center RCT. The participants will be randomly assigned to pharmacopuncture or physical therapy group to receive their respective 8-session treatments for 4 weeks. The primary outcome is the visual analogue scale of neck pain. Secondary outcomes is the Northwick Park questionnaire, visual analogue scale of radiating arm pain, numeric rating scale of the neck and arm bothersomeness, neck disability index, patient global impression of change, short form-12 health survey version 2, and 5-level EuroQol-5 dimension. Discussion: This is a protocol for a pragmatic RCT that would attempt ...
Source: Medicine - July 31, 2020 Category: Internal Medicine Tags: Research Article: Study Protocol Clinical Trial Source Type: research

Icariin Ameliorates Lower Back Pain in Rats via Suppressing the Secretion of Cytokine-Induced Neutrophil Chemoatractant-1.
Conclusion: ICA is a novel herbal extract to relieve LBP, and it may be a promising alternative pain killer in the future. PMID: 32802846 [PubMed - in process]
Source: Biomed Res - August 19, 2020 Category: Research Authors: Li J, Luo M, Wang S, Jin G, Han Z, Ma Y, Tang G, Guo Z Tags: Biomed Res Int Source Type: research

Analgesic effects of cuminic alcohol (4-isopropylbenzyl alcohol), a monocyclic terpenoid, in animal models of nociceptive and neuropathic pain: Role of opioid receptors, L-arginine/NO/cGMP pathway, and inflammatory cytokines
Eur J Pharmacol. 2021 Mar 31:174075. doi: 10.1016/j.ejphar.2021.174075. Online ahead of print.ABSTRACTCuminic alcohol (4-isopropylbenzyl alcohol; 4-IPBA) is a monocyclic terpenoid found in the analgesic medicinal plants Cuminum cyminum and Bunium persicum. The current study assessed the analgesic effects of 4-IPBA in different animal models of pain. Hot plate, formalin, and acetic acid tests were used to evaluate nociceptive pain in mice. The involvement of opioid receptors and the L-arginine/NO/cGMP/K+ channel pathway in 4-IPBA effects were investigated. Allodynia and hyperalgesia were assessed following peripheral neurop...
Source: European Journal of Pharmacology - April 3, 2021 Category: Drugs & Pharmacology Authors: Mohammad Abbas Sheikholeslami Shiva Ghafghazi Siavash Parvardeh Sheida Koohsari Saeed Haji Aghajani Ramin Pouriran Leila Alipour Vaezi Source Type: research

Herbal nutraceutical treatment of chronic prostatitis –chronic pelvic pain syndrome: a literature review
AbstractChronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is the most frequent form of prostatitis, and has a serious impact on patients ’ quality of life, and causes severe symptoms. The pain in the pelvic, perineal and penile areas, lower abdominal pain, and pain during urination or ejaculation are the main complaints of CP/CPPS. The underlying complex and unknown pathophysiology of this syndrome have made the management of CP/CP PS and the availability of monotherapy challenging. To identify an effective monotherapy, a plethora of clinical trials failed due to its puzzling etiology. Antibiotics, anti-inflamma...
Source: International Urology and Nephrology - April 27, 2021 Category: Urology & Nephrology Source Type: research

Molecules, Vol. 26, Pages 5434: Antinociceptive Synergism of Pomegranate Peel Extract and Acetylsalicylic Acid in an Animal Pain Model
o-Morales Several modern drugs, which are derived from traditional herbal medicine are used in contemporary pharmacotherapy. Currently, the study of drug–plant interactions in pain has increased in recent years, looking for greater efficacy of the drug and reduce side effects. The antinociception induced by intragastric co-administration of the combination of pomegranate peel extract (PoPEx) and acetylsalicylic acid (ASA) was assessed using the isobolographic analysis in formalin test (nociceptive and inflammatory pain). The effective dose that produced 30% of antinociception (ED30) was calculated for both drugs from...
Source: Molecules - September 7, 2021 Category: Chemistry Authors: Jos é Antonio Guerrero-Solano Mirandeli Bautista Claudia Vel ázquez-González Minarda De la O-Arciniega Luis Guillermo Gonz ález-Olivares Monserrat Fern ández-Moya Osmar Antonio Jaramillo-Morales Tags: Article Source Type: research

The Effects of Elgucare on Degenerated Intervertebral Disc-Induced Low Back Pain and Disc Regeneration: A Clinical Trial
CONCLUSIONS: Elgucare can increase the water retention and height of IVDs and reduce LBP, thereby enhancing quality of life. Therefore, Elgucare can potentially be used as a clinical supplement.PMID:34790253 | PMC:PMC8592736 | DOI:10.1155/2021/5824956
Source: Computational and Mathematical Methods in Medicine - November 18, 2021 Category: Statistics Authors: Wen-Cheng Lo Yu Ting Chen Chen Ching Chen Source Type: research

East Asian herbal medicine for cancer pain: A protocol for systematic review and meta-analysis with using association rule analysis to identify core herb pattern
Conclusions: Based on the results of this review, it is expected that the efficacy and safety of East Asian herbal medicine for cancer pain may be confirmed. In addition, it will be possible to derivation of a core herb pattern related to this research topic through additional association rule mining analysis.
Source: Medicine - November 12, 2021 Category: Internal Medicine Tags: Research Article: Study Protocol Systematic Review Source Type: research

The Effects of Elgucare on Degenerated Intervertebral Disc-Induced Low Back Pain and Disc Regeneration: A Clinical Trial
CONCLUSIONS: Elgucare can increase the water retention and height of IVDs and reduce LBP, thereby enhancing quality of life. Therefore, Elgucare can potentially be used as a clinical supplement.PMID:34790253 | PMC:PMC8592736 | DOI:10.1155/2021/5824956
Source: Computational and Mathematical Methods in Medicine - November 18, 2021 Category: Statistics Authors: Wen-Cheng Lo Yu Ting Chen Chen Ching Chen Source Type: research

Tamarindus indica Seed Extract-Based Botanical Compositions Alleviate Knee Pain and Improve Joint Function in Mild-to-Moderate Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Clinical Study
Evid Based Complement Alternat Med. 2022 Jan 19;2022:2226139. doi: 10.1155/2022/2226139. eCollection 2022.ABSTRACTOBJECTIVE: Knee pain and reduced joint function affect the quality of life of subjects suffering from knee osteoarthritis (KOA). The present randomized, double-blind, placebo-controlled study aimed to assess the clinical efficacy of two botanical compositions, NXT15906F6 and NXT19185, in pain relief and improvement in the musculoskeletal function of knee osteoarthritis (KOA) subjects. NXT15906F6 contains ethanol/aqueous extract of Tamarindus indica seeds and aqueous ethanol extract of Curcuma longa rhizome, and...
Source: Evidence-based Complementary and Alternative Medicine - January 31, 2022 Category: Complementary Medicine Authors: Sanjeev Kumar Kare Vineet Vinay Katarzyna Maresz Victor Prisk Hogne Vik Source Type: research

< em > Angelica dahurica < /em > Extracts Attenuate CFA-Induced Inflammatory Pain via TRPV1 in Mice
In this study, we used behavioral tests to assess the analgesic effect of the ADE (Angelica dahurica extracts) on CFA (complete Freund's adjuvant)-induced inflammatory pain mice models. TRPV1 (Transient Receptor Potential Cation Channel Subfamily V Member 1) protein activity in dorsal root ganglion (DRG) was assessed with a calcium imaging assay. TRPV1 expression was detected with western blot and immunohistochemistry. Then, we examined the constituents of ADE using combined ultra-performance liquid chromatography-quadrupole time-of-light mass spectrometry (UPLC/Q-TOF-MS). Our results showed that ADE effectively attenuated...
Source: Evidence-based Complementary and Alternative Medicine - June 3, 2022 Category: Complementary Medicine Authors: Chan Zhu Meiyuan Wang Jun Guo Shu Lan Su Guang Yu Yan Yang Yuan Zhou Zongxiang Tang Source Type: research