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Nutrition: Vitamin A
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Total 19019 results found since Jan 2013.
Overexpression of microRNA-130a-3p suppresses glucose lipid levels and oxidative damage in diabetic retinopathy mice via modulating cell division cycle 42
J Genet. 2023;102:41.ABSTRACTMicroRNA (miR)-130a-3p has been unraveled to exert effects on diabetes. However, the research for probing its role in diabetic retinopathy (DR) is limited. Our study intends to unravel the regulatory effects of miR-130a-3p on DR development via cell division cycle 42 (CDC42). The DR mouse model was established and the serum sample of DR patients was collected. The levels of miR- 130a-3p and CDC42 in DR mice and patients were detected. The nucleic acids modified miR-130a-3p or CDC42 were injected into DR mice to examine the change of glucose lipid levels, visual acuity, oxidative response and th...
Source: Journal of Genetics - September 12, 2023 Category: Genetics & Stem Cells Authors: Hui Wang Xu Dong Jing Zhou Caoyu Sun Source Type: research
Immunoregulation mechanism of VEGF signaling pathway inhibitors and its efficacy on the kidney
Am J Med Sci. 2023 Sep 10:S0002-9629(23)01330-7. doi: 10.1016/j.amjms.2023.09.005. Online ahead of print.ABSTRACTAngiogenesis and immunosuppression are closely related pathophysiologic processes. Widely prescribed in malignant tumor and proliferative retinal lesions, VEGF signaling pathway inhibitors may cause hypertension and renal injury in some patients, presenting with proteinuria, nephrotic syndrome, renal failure and thrombotic microangiopathy. VEGF signaling pathway inhibitors block the action of both VEGF-A and VEGF-C. However, VEGF-A and VEGF-C produced by podocytes are vital to maintain the physiological function...
Source: The American Journal of the Medical Sciences - September 12, 2023 Category: General Medicine Authors: Jun Li Xiao-Lin Li Chun-Qing Li Source Type: research
Overexpression of microRNA-130a-3p suppresses glucose lipid levels and oxidative damage in diabetic retinopathy mice via modulating cell division cycle 42
J Genet. 2023;102:41.ABSTRACTMicroRNA (miR)-130a-3p has been unraveled to exert effects on diabetes. However, the research for probing its role in diabetic retinopathy (DR) is limited. Our study intends to unravel the regulatory effects of miR-130a-3p on DR development via cell division cycle 42 (CDC42). The DR mouse model was established and the serum sample of DR patients was collected. The levels of miR- 130a-3p and CDC42 in DR mice and patients were detected. The nucleic acids modified miR-130a-3p or CDC42 were injected into DR mice to examine the change of glucose lipid levels, visual acuity, oxidative response and th...
Source: Journal of Genetics - September 12, 2023 Category: Genetics & Stem Cells Authors: Hui Wang Xu Dong Jing Zhou Caoyu Sun Source Type: research
Immunoregulation mechanism of VEGF signaling pathway inhibitors and its efficacy on the kidney
Am J Med Sci. 2023 Sep 10:S0002-9629(23)01330-7. doi: 10.1016/j.amjms.2023.09.005. Online ahead of print.ABSTRACTAngiogenesis and immunosuppression are closely related pathophysiologic processes. Widely prescribed in malignant tumor and proliferative retinal lesions, VEGF signaling pathway inhibitors may cause hypertension and renal injury in some patients, presenting with proteinuria, nephrotic syndrome, renal failure and thrombotic microangiopathy. VEGF signaling pathway inhibitors block the action of both VEGF-A and VEGF-C. However, VEGF-A and VEGF-C produced by podocytes are vital to maintain the physiological function...
Source: The American Journal of the Medical Sciences - September 12, 2023 Category: General Medicine Authors: Jun Li Xiao-Lin Li Chun-Qing Li Source Type: research
Overexpression of microRNA-130a-3p suppresses glucose lipid levels and oxidative damage in diabetic retinopathy mice via modulating cell division cycle 42
J Genet. 2023;102:41.ABSTRACTMicroRNA (miR)-130a-3p has been unraveled to exert effects on diabetes. However, the research for probing its role in diabetic retinopathy (DR) is limited. Our study intends to unravel the regulatory effects of miR-130a-3p on DR development via cell division cycle 42 (CDC42). The DR mouse model was established and the serum sample of DR patients was collected. The levels of miR- 130a-3p and CDC42 in DR mice and patients were detected. The nucleic acids modified miR-130a-3p or CDC42 were injected into DR mice to examine the change of glucose lipid levels, visual acuity, oxidative response and th...
Source: Journal of Genetics - September 12, 2023 Category: Genetics & Stem Cells Authors: Hui Wang Xu Dong Jing Zhou Caoyu Sun Source Type: research
Vitamin A biomarkers were associated with AGP and CRP over the course of a human norovirus challenge infection
Br J Nutr. 2023 Sep 11:1-19. doi: 10.1017/S0007114523002076. Online ahead of print.ABSTRACTRetinol binding protein (RBP) is used as a proxy for retinol in population-based assessments of vitamin A deficiency (VAD) for cost-effectiveness and feasibility. When the cutoff of <0.7 mol/L for retinol is applied to RBP to define VAD, an equivalence of the two biomarkers is assumed. Evidence suggests that the relationship between retinol and RBP is not 1:1, particularly in populations with a high burden of infection or inflammation. The goal of this analysis was to longitudinally evaluate the retinol:RBP ratio over one month of...
Source: The British Journal of Nutrition - September 11, 2023 Category: Nutrition Authors: Courtney P Victor Juan S Leon Anne M Williams Source Type: research
Optical Coherence Tomography Angiography Metrics in Diabetes: Focusing on Diabetic Retinopathy and Carotid Atherosclerosis
CONCLUSIONS: Focusing on IRBFD and CRBFD in the 3*3 window of OCTA allows for a more sensitive prediction of the occurrence of DR in diabetic patients. Meanwhile, the quantitative microvascular information provided by OCTA and the occurrence of DPVD may be crucial for diagnosing carotid atherosclerosis. For T2DM patients, we also propose the possibility of FAZ in the 3*3 window as a potential diagnostic indicator.PMID:37696316 | DOI:10.1016/j.pdpdt.2023.103799
Source: Atherosclerosis - September 11, 2023 Category: Cardiology Authors: Xiongyi Yang Guoguo Yi Yanxia Chen Kedi Ma Bingxu Chen Shilong Liang Cong Zheng Shibei Ai Mingzhe Cao Min Fu Source Type: research
The profile of adipokines associated with fibrosis and impaired microcirculation in systemic sclerosis
CONCLUSION: Adipsin may be considered a pivotal protein in the development of both fibrosis and impaired microcirculation. Its abnormal concentration reflects the intensity of skin thickening and the presence of pulmonary arterial hypertension. Adipsin, visfatin, and apelin are adipose tissue-derived molecules associated with digital vasculopathy.PMID:37696138 | DOI:10.1016/j.advms.2023.09.001
Source: Advances in Medical Sciences - September 11, 2023 Category: Biomedical Science Authors: Anna Niemczyk Anna Wa śkiel-Burnat Micha ł Zaremba Joanna Czuwara Lidia Rudnicka Source Type: research
Role of Vitamins in Cardiovascular Health: Know Your Facts-Part 2
Curr Vasc Pharmacol. 2023 Sep 11. doi: 10.2174/1570161121666230911115725. Online ahead of print.ABSTRACTCardiovascular disease (CVD) is a major cause of morbidity/mortality world-wide, hence preventive interventions are crucial. Observational data showing beneficial CV-effects of vitamin supplements, promoted by self-proclaimed experts, have led to ~50% of Americans using multivitamins; this practice has culminated into a multi-billion-dollar business. However, robust evidence is lacking, and certain vitamins might incur harm. This two-part review focuses on the attributes or concerns about specific vitamin consumption on ...
Source: Current Vascular Pharmacology - September 11, 2023 Category: Drugs & Pharmacology Authors: Antonis A Manolis Theodora A Manolis Helen Melita Antonis S Manolis Source Type: research
Evaluation of Long-Term Nutrition Outcomes After Duodenal Switch: A Systematic Review and Meta-Analysis
CONCLUSIONS: Despite displaying comparable nutrition-related outcomes to mid-term follow-up, our study demonstrated that BPD-DS could result in a high level of long-term nutrition deficiency after BPD-DS for selected patients. However, further randomized controlled studies with standardized supplementation regimens and improvement in compliance are necessary to evaluate and prevent long-term nutritional deficiencies after BPD-DS.PMID:37694730 | DOI:10.1177/00031348231201886
Source: The American Surgeon - September 11, 2023 Category: Surgery Authors: Hayato Nakanishi Kamal Abi Mosleh Mohammad Al-Kordi Katie Marrero Mohammad Kermansaravi S Scott Davis Benjamin Clapp Omar M Ghanem Source Type: research
A Review on the Cytotoxicity and Antibacterial Effect of Marine Organisms of Persian Gulf
Adv Biomed Res. 2023 Jul 27;12:195. doi: 10.4103/abr.abr_290_22. eCollection 2023.ABSTRACTMarine organisms contain several natural products and bioactive compounds, including hydrolyzed proteins, antioxidant peptides, gelatin, collagen, ω-3 unsaturated fatty acids, vitamin A, vitamin D, calcium phosphate, hydroxyapatite, chitosan, lectin, and various toxins. They can inhibit diverse diseases, be used in pharmaceutical compounds, or as antibiotics and pigments. In this regard, these microorganisms are of crucial medicinal and economical importance. Thanks to new technologies and advanced laboratory methods, bioactive compo...
Source: Biomed Res - September 11, 2023 Category: Research Authors: Seyed Erfan Mousavi Sheyda Razaghi Nafiseh Emami Afsaneh Yegdaneh Source Type: research
