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Morphological and molecular characterization of Chloromyxum dasyatidis n. sp. (Myxosporea: Chloromyxidae) in the common stingray Dasyatis pastinaca (Linnaeus) from Tunisian waters (Central Mediterranean Sea)
Syst Parasitol. 2023 Sep 9. doi: 10.1007/s11230-023-10111-6. Online ahead of print.ABSTRACTA new species of Chloromyxum Mingazzini, 1890, C. dasyatidis n. sp., is described from the gallbladder of the elasmobranch fish Dasyatis pastinaca (Linnaeus) from the Mediterranean coast off Tunisia. Mature myxospores were subspherical measuring 13.0 ± 0.3 (12.5-13.9) µm in length, 11.3 ± 0.5 (10.2-12.2) µm in width, and 11.8 ± 0.5 (11.4-12.7) µm in thickness. Four pyriform polar capsules 4.4 ± 0.3 (4.0-4.9) µm long and 3.5 ± 0.3 (3.0-3.8) µm wide. Valves were ornamented by 5 to 7 elevated surface ridges and displayed short...
Source: Systematic Parasitology - September 9, 2023 Category: Parasitology Authors: Luis F Rangel Amira Elloumi Yann Quilichini Maria J Santos Sihem Bahri Source Type: research
Her work paved the way for blockbuster obesity drugs. Now, she ’s fighting for recognition
When Svetlana Mojsov heard the spring 2021 announcement, she was startled. The Canada Gairdner International Award, a prestigious biomedical research prize, would be bestowed on three scientists for work underpinning the diabetes and obesity drugs that have exploded in popularity in recent years. “I was really upset,” recalls Mojsov, a chemist at Rockefeller University.
The Gairdner award marked the third time in 4 years that the same trio of scientists—Joel Habener at Massachusetts General Hospital (MGH), Daniel Drucker at the University of Toronto, and Jens Juul Holst at the University of Copenhagen—were hon...
Source: Science of Aging Knowledge Environment - September 8, 2023 Category: Geriatrics Source Type: research
Body distribution and ecotoxicological effect of nanoplastics in freshwater fish, Zacco platypus
This study investigated the organ accumulation and toxic effects of 50 nm polystyrene nanoplastics (PS-NPs) in Zacco platypus (Z. platypus; also known as pale chub fish) using pyrolyzer-gas chromatography-mass spectrometry (Pyr-GC/MS). PS-NPs accumulated in Z. platypus' brain, digestive tract, branchia, and liver, causing changes at cellular level. Over a 14-day exposure, the accumulated PS-NPs led to observable changes in fish behavior (e.g., Total traveled distance and maximum velocity). In addition, the oxidative stress in each organ of Z. platypus increased as the exposure concentration of PS-NPs increased. This study ...
Source: Chemosphere - September 8, 2023 Category: Chemistry Authors: Jiwon Choi Yeowool Choi Sang Don Kim Source Type: research
Circular RNA sequencing identified circARNTL2 as a pathogenic factor in psoriasis by facilitating proliferation and cell cycle progression of keratinocytes
Clin Immunol. 2023 Sep 6:109766. doi: 10.1016/j.clim.2023.109766. Online ahead of print.ABSTRACTPsoriasis is a chronic recurrent skin disease, with excessive proliferation of keratinocytes. Recent studies indicated the pathogenic roles of circular RNA (circRNA) in psoriasis. Here, we screened the circRNA profiles from five psoriatic skin lesions and five normal skin tissues by circRNA sequencing and identified 1118 differentially expressed circRNAs (DECs) between psoriatic and normal groups. Among these DECs, high abundant circARNTL2 has been proven upregulated in psoriatic skin lesions by RT-qPCR assay. Then, the head-to-...
Source: Clinical Immunology - September 8, 2023 Category: Allergy & Immunology Authors: Suhan Zhang Yanshan Zhu Siying Li Peng Zhang Min Deng Yuwen Su Ruifang Wu Weiyun Shen Source Type: research
Fish Scale Derived Hydroxyapatite Incorporated 3D Printed PLA Scaffold for Bone Tissue Engineering
New J. Chem., 2023, Accepted Manuscript DOI: 10.1039/D3NJ03005A, PaperNEBU George THOMAS, Yogesh Bharat Dalvi, Natalia Fijol, Joy Shilpa, Rekha Unni, P. K. Binsi, Mekha Grace Varghese, R. Reshmy, Aji Mathew, Anil Sukumaran Bone defect repair, particularly in the alveolar region, remains a significant hurdle in periodontics. In recent years, the spotlight in regenerative medicine has fallen on 3D-printed bone scaffolds, especially those... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - September 8, 2023 Category: Chemistry Authors: NEBU George THOMAS Source Type: research
Exploring the impact of PVC and PVA microplastics on zebrafish tissue using multi-spectral imaging, Optical Coherence Tomography (OCT), and biospeckle OCT (bOCT)
This study investigates the effect of Polyvinyl chloride (PVC) and Polyvinyl alcohol (PVA) microplastics in zebrafish by using multi-spectral imaging (MSI), Optical Coherence Tomography (OCT), and Biospeckle OCT (bOCT). These techniques allow for long-term studies in the fish without invasive procedures in real-time. Zebrafish were exposed to Nile red labeled PVC and PVA for 21 days with 500mg/L concentration. Image acquisition and analysis were performed every five days till the end of the study. MSI images revealed deposition of microplastics in the gills region of the fish; some diffused deposition was seen throughout t...
Source: Chemosphere - September 7, 2023 Category: Chemistry Authors: Pooja C Asani Zoya Alam Raju Poddar Source Type: research
Relationship of Mercury and Selenium in Ocean Fish Frequently Consumed in the Seychelles: A Comparison to Levels in Ocean Fish Consumed in the US
Neurotoxicology. 2023 Sep 5:S0161-813X(23)00108-0. doi: 10.1016/j.neuro.2023.09.001. Online ahead of print.ABSTRACTWe characterized mercury and selenium in the fish consumed in the Seychelles Islands to determine if their levels are similar to fish consumed in the US. A secondary aim was to examine whether fish weight and species predict mercury and selenium in fish consumed in the Seychelles. We measured total mercury (THg) and selenium (Se) content of 10 samples from each of the 19 most frequently consumed fish species in Seychelles and for each calculated the Se:Hg molar ratios and the Selenium Health Benefit Value Inde...
Source: Neurotoxicology - September 7, 2023 Category: Neurology Authors: Grazyna Zareba Donald Harrington Tom Scrimale Aubrey LeEsperance Gene E Watson Edwin van Wijngaarden Conrad F Shamlaye Tyler Nicholas Gary J Myers Sally W Thurston Source Type: research
Exploring the impact of PVC and PVA microplastics on zebrafish tissue using multi-spectral imaging, Optical Coherence Tomography (OCT), and biospeckle OCT (bOCT)
This study investigates the effect of Polyvinyl chloride (PVC) and Polyvinyl alcohol (PVA) microplastics in zebrafish by using multi-spectral imaging (MSI), Optical Coherence Tomography (OCT), and Biospeckle OCT (bOCT). These techniques allow for long-term studies in the fish without invasive procedures in real-time. Zebrafish were exposed to Nile red labeled PVC and PVA for 21 days with 500mg/L concentration. Image acquisition and analysis were performed every five days till the end of the study. MSI images revealed deposition of microplastics in the gills region of the fish; some diffused deposition was seen throughout t...
Source: Chemosphere - September 7, 2023 Category: Chemistry Authors: Pooja C Asani Zoya Alam Raju Poddar Source Type: research
Effects of microfiber and bead microplastic exposure in the goldfish Carassius auratus: Bioaccumulation, antioxidant responses, and cell damage
Aquat Toxicol. 2023 Sep 4;263:106684. doi: 10.1016/j.aquatox.2023.106684. Online ahead of print.ABSTRACTWe confirmed antioxidant-related gene expression, bioaccumulation, and cell damage following exposure to various microplastics in vivo and in vitro in the goldfish Carassius auratus. Exposure of C. auratus to a 500 µm fiber-type microplastic environment (MF; 10 and 100 fibers/L) and two sizes (0.2 and 1.0 µm) of beads (MB; 10 and 100 beads/L) for 120 h increased superoxide dismutase (SOD) mRNA expression in the liver until 24 h followed by a decrease. Whereas, catalase (CAT) mRNA expression increased from 12 h to the e...
Source: Aquatic Toxicology - September 7, 2023 Category: Toxicology Authors: Jin A Kim Min Ju Kim Young-Su Park Chang-Keun Kang Jun-Hwan Kim Cheol Young Choi Source Type: research
The ghrelin receptor GHSR has two efficient agonists in the lobe-finned fish Latimeria chalumnae
Biochem Biophys Res Commun. 2023 Sep 3;679:110-115. doi: 10.1016/j.bbrc.2023.09.002. Online ahead of print.ABSTRACTThe peptide hormone ghrelin (an agonist) and LEAP2 (an antagonist) play important functions in energy metabolism via their receptor GHSR, an A-class G protein-coupled receptor. Ghrelin, LEAP2, and GHSR are widely present from fishes to mammals. However, our recent study suggested that fish GHSRs have different binding properties to ghrelin: a GHSR from the lobe-finned fish Latimeria chalumnae (coelacanth) is efficiently activated by ghrelin, but GHSRs from the ray-finned fish Danio rerio (zebrafish) and Larimi...
Source: Biochemical and Biophysical Research communications - September 7, 2023 Category: Biochemistry Authors: Hao-Zheng Li Ya-Fen Wang Yong-Shan Zheng Ya-Li Liu Zeng-Guang Xu Zhan-Yun Guo Source Type: research
A hybrid RNA FISH immunofluorescence protocol on Drosophila polytene chromosomes
BMC Res Notes. 2023 Sep 7;16(1):197. doi: 10.1186/s13104-023-06482-0.ABSTRACTOBJECTIVES: Investigating protein-DNA interactions is imperative to understanding fundamental concepts such as cell growth, differentiation, and cell development in many systems. Sequencing techniques such as ChIP-seq can yield genome-wide DNA binding profiles of transcription factors; however this assay can be expensive, time-consuming, may not be informative for repetitive regions of the genome, and depend heavily upon antibody suitability. Combining DNA fluorescence in situ hybridization (FISH) with immunofluorescence (IF) is a quicker and inex...
Source: Cell Research - September 7, 2023 Category: Cytology Authors: Hannah E Gilbonio Gwyn L Puckett Erica Nguyen Leila E Rieder Source Type: research
