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Male kidney-specific BMAL1 knockout mice are protected from Potassium-deficient, high salt diet-induced blood pressure increases
Am J Physiol Renal Physiol. 2023 Sep 14. doi: 10.1152/ajprenal.00126.2023. Online ahead of print.ABSTRACTThe circadian clock protein BMAL1 is a transcription factor that impacts kidney function, including blood pressure (BP) control. Previously, we showed that male, but not female, kidney-specific cadherin Cre positive BMAL1 knockout mice (KS-BMAL1 KO) exhibit lower BP compared to littermate controls. The goal of this study was to determine the BP phenotype and immune response in male KS-BMAL1 KO in response to a low potassium, high salt diet (LKHS). BP, renal inflammatory markers and immune cells were measured in male mic...
Source: American Journal of Physiology. Renal Physiology - September 14, 2023 Category: Physiology Authors: G Ryan Crislip Hannah M Costello Alexandria Juffre Kit-Yan Cheng I Jeanette Lynch Jermaine G Johnston Charles B Drucker Phillip Bratanatawira Annanya Agarwal Victor M Mendez Ryanne S Thelwell Lauren G Douma Charles S Wingo Abdel A Alli Yogesh M Scindia Mi Source Type: research
AEE alleviates ox-LDL-induced lipid accumulation and inflammation in macrophages
Biomed Pharmacother. 2023 Sep 12;167:115486. doi: 10.1016/j.biopha.2023.115486. Online ahead of print.ABSTRACTAtherosclerosis is a chronic immune inflammatory disease. Aspirin eugenol ester (AEE) is a novel safe and non-toxic compound with many pharmacological effects such as anti-inflammatory, anti-hyperlipidemic and anti-thrombotic action. In order to investigate the effect of AEE on the inhibition of aortic lipid plaque formation and macrophage-derived foam cell formation induced by oxidized low density lipoprotein (ox-LDL), in vivo atherosclerosis model by feeding ApoE-/- mice with a high-fat diet and foam cells format...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 14, 2023 Category: Drugs & Pharmacology Authors: Ya-Xian Liu Xi-Wang Liu Ya-Jun Yang Shi-Hong Li Li-Xia Bai Wen-Bo Ge Xiao Xu Cun Li Jian-Yong Li Zhe Qin Source Type: research
Intestinal microbiota: A bridge between intermittent fasting and tumors
Biomed Pharmacother. 2023 Sep 12;167:115484. doi: 10.1016/j.biopha.2023.115484. Online ahead of print.ABSTRACTIntestinal microbiota and their metabolites are essential for maintaining intestinal health, regulating inflammatory responses, and enhancing the body's immune function. An increasing number of studies have shown that the intestinal microbiota is tightly tied to tumorigenesis and intervention effects. Intermittent fasting (IF) is a method of cyclic dietary restriction that can improve energy metabolism, prolong lifespan, and reduce the progression of various diseases, including tumors. IF can affect the energy meta...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 14, 2023 Category: Drugs & Pharmacology Authors: Jing Liu Nan Shao Hui Qiu Juanjuan Zhao Chao Chen Jiajia Wan Zhixu He Xu Zhao Lin Xu Source Type: research
Zinc intake, SLC30A8 rs3802177 polymorphism, and colorectal cancer risk in a Korean population: a case-control study
CONCLUSIONS: In summary, our findings suggest an inverse association between dietary zinc intake and CRC risk, and this relationship may be modified by SLC30A8 rs3802177 polymorphism.PMID:37707576 | DOI:10.1007/s00432-023-05381-y
Source: Clinical Colorectal Cancer - September 14, 2023 Category: Cancer & Oncology Authors: Linh Thi Dieu Nguyen Madhawa Gunathilake Jeonghee Lee Jae Hwan Oh Hee Jin Chang Dae Kyung Sohn Aesun Shin Jeongseon Kim Source Type: research
Appearance comparison on Instagram: The impact of fitspiration and transformation imagery on young women's body satisfaction
Eat Behav. 2023 Sep 12;51:101812. doi: 10.1016/j.eatbeh.2023.101812. Online ahead of print.ABSTRACTFitspiration, or imagery of thin muscular individuals that displays their physiques while posing or exercising, is a popular type of content on Instagram which ostensibly exists to encourage individuals to engage in a healthy lifestyle. A subtype of fitspiration imagery, "transformation" imagery, depicts physical changes following a "lifestyle change" involving diet and exercise. Despite its intentions, fitspiration imagery largely promotes one idealized body type (the fit ideal) and can be accompanied by messages encouraging...
Source: Eating Behaviors - September 14, 2023 Category: Eating Disorders & Weight Management Authors: Lindsay Samson Shannon L Zaitsoff Source Type: research
Confounding Effects of Tamoxifen: Cautionary and Practical Considerations for the Use of Tamoxifen-Inducible Mouse Models in Atherosclerosis Research
CONCLUSIONS: In this study, we establish that tamoxifen administration results in decreased serum cholesterol, decreased plaque formation, and increased hepatic lipid accumulation. These alterations represent significant confounding variables in atherosclerosis research, and we urge future investigators to take these findings into consideration when planning and executing their own atherosclerosis experiments.PMID:37706321 | DOI:10.1161/ATVBAHA.123.319922
Source: Arteriosclerosis, Thrombosis and Vascular Biology - September 14, 2023 Category: Cardiology Authors: Allison M Dubner Sizhao Lu Austin J Jolly Tysen Noble Tyler Hinthorn Raphael A Nemenoff Karen S Moulton Mark W Majesky Mary C M Weiser-Evans Source Type: research
The effects of brief diet and anti-diet social media videos on body image and eating concerns among young women
Eat Behav. 2023 Sep 12;51:101811. doi: 10.1016/j.eatbeh.2023.101811. Online ahead of print.ABSTRACTThe effects of photo-based platforms on body image concerns are well documented, yet it is unknown whether these effects replicate across video-based platforms such as TikTok. Thus, this experimental study aimed to examine the relationship between video-based platform use and body image. Women aged 18 to 21 (n = 421) were randomly assigned to watch two brief, consecutive TikTok videos in one of three conditions: (1) diet culture, (2) anti-diet, (3) neutral. Participants allocated to the anti-diet condition reported greater in...
Source: Eating Behaviors - September 14, 2023 Category: Eating Disorders & Weight Management Authors: Angelica Fiuza Rachel F Rodgers Source Type: research
Dietary intake in individuals with phenylketonuria: an integrative review
CONCLUSION: most individuals with PKU have low energy, protein and fiber intake, adequate lipid intake, and high carbohydrate intake. Metabolic control of the disease is still a challenge in all countries. Nutritional strategies to improve dietary nutritional composition and phenylalanine blood levels in individuals with PKU remain an urgent issue.PMID:37705455 | DOI:10.20960/nh.04579
Source: Nutricion Hospitalaria - September 14, 2023 Category: Nutrition Authors: Thais Regina Mezzomo Marcia Regina Messaggi Gomes Dias Tatiane Santos Rosana Marques Pereira Source Type: research
Effect of a personalized nutritional intervention program on nutritional status, quality of life and mortality in hemodialysis patients
CONCLUSION: the results of this study suggest that personalized NIP contributed to improved nutritional status, QoL and survival in HD patients.PMID:37705451 | DOI:10.20960/nh.04756
Source: Nutricion Hospitalaria - September 14, 2023 Category: Nutrition Authors: Luc ía Visiedo Francisca L ópez Francisco Rivas-Ruiz Bego ña Tortajada Rafael Gim énez Martínez Jimena Abil és Source Type: research
Optimizing carbohydrate intake from drugs in epileptic patients on a ketogenic diet
Nutr Hosp. 2023 Sep 1. doi: 10.20960/nh.04798. Online ahead of print.NO ABSTRACTPMID:37705443 | DOI:10.20960/nh.04798
Source: Nutricion Hospitalaria - September 14, 2023 Category: Nutrition Authors: Javier Coraz ón Villanueva Mar ía de la Torre Ortíz Virg ínia Puebla García Jos é Manuel Martínez Sesmero Source Type: research
Factors associated with academic performance in adolescents from La Rioja (Spain): lifestyle habits, health indicators, and sociodemographic factors
CONCLUSIONS: interventions aimed at combating academic failure should take into account the aforementioned associated factors, with special emphasis on the most vulnerable groups such as males, those with lower socioeconomic status, and those who follow unhealthy lifestyle habits.PMID:37705442 | DOI:10.20960/nh.04599
Source: Nutricion Hospitalaria - September 14, 2023 Category: Nutrition Authors: Ra úl Jiménez Boraita Josep Mar ía Dalmau Torres Esther Gargallo Ibort Daniel Arriscado Alsina Source Type: research
Protective effect of dietary micronutrients on gastric cancer risk among Jordanians
CONCLUSIONS: our data support favorable effects of dietary consumption of some vitamins and minerals against GC risk.PMID:37705441 | DOI:10.20960/nh.04547
Source: Nutricion Hospitalaria - September 14, 2023 Category: Nutrition Authors: Sabika Allehdan Shatha S Hammad Razan M Alatrash Tareq Al-Jaberi Ahmad Hushki Shirin Yacoub Mohammad Dahoud Tahra Elobeid Reema Tayyem Tayyem Source Type: research
Effect of various dietary fructose concentrations on the gallstone formation process in mice
CONCLUSION: changes in plasma, liver and bile lipids were only observed at very high fructose concentrations diets. We conclude that fructose apparently does not alter the gallstone formation process in our experimental model.PMID:37705438 | DOI:10.20960/nh.04610
Source: Nutricion Hospitalaria - September 14, 2023 Category: Nutrition Authors: Reginald Del Pozo Iribarren Lorena Mardones Marcelo Villagr án Katia Mu ñoz Luciano Troncoso Maximiliano Mellado Mirna Mu ñoz Source Type: research
AEE alleviates ox-LDL-induced lipid accumulation and inflammation in macrophages
Biomed Pharmacother. 2023 Sep 12;167:115486. doi: 10.1016/j.biopha.2023.115486. Online ahead of print.ABSTRACTAtherosclerosis is a chronic immune inflammatory disease. Aspirin eugenol ester (AEE) is a novel safe and non-toxic compound with many pharmacological effects such as anti-inflammatory, anti-hyperlipidemic and anti-thrombotic action. In order to investigate the effect of AEE on the inhibition of aortic lipid plaque formation and macrophage-derived foam cell formation induced by oxidized low density lipoprotein (ox-LDL), in vivo atherosclerosis model by feeding ApoE-/- mice with a high-fat diet and foam cells format...
Source: Atherosclerosis - September 14, 2023 Category: Cardiology Authors: Ya-Xian Liu Xi-Wang Liu Ya-Jun Yang Shi-Hong Li Li-Xia Bai Wen-Bo Ge Xiao Xu Cun Li Jian-Yong Li Zhe Qin Source Type: research
Confounding Effects of Tamoxifen: Cautionary and Practical Considerations for the Use of Tamoxifen-Inducible Mouse Models in Atherosclerosis Research
CONCLUSIONS: In this study, we establish that tamoxifen administration results in decreased serum cholesterol, decreased plaque formation, and increased hepatic lipid accumulation. These alterations represent significant confounding variables in atherosclerosis research, and we urge future investigators to take these findings into consideration when planning and executing their own atherosclerosis experiments.PMID:37706321 | DOI:10.1161/ATVBAHA.123.319922
Source: Atherosclerosis - September 14, 2023 Category: Cardiology Authors: Allison M Dubner Sizhao Lu Austin J Jolly Tysen Noble Tyler Hinthorn Raphael A Nemenoff Karen S Moulton Mark W Majesky Mary C M Weiser-Evans Source Type: research
