• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Evaluation the effect of dietary vitamin E, sesamin and thymoquinone bioactive compounds on immunological response, intestinal traits and MUC-2 gene expression in broiler Japanese quails ( < em > Coturnix japonica < /em > )
Anim Biotechnol. 2023 Sep 20:1-11. doi: 10.1080/10495398.2023.2259437. Online ahead of print.ABSTRACTThe current study was performed to determine the effect of dietary vitamin E, sesamin and thymoquinone bioactive lignans derived from sesame and black seed on immunological response, intestinal traits and Mucin2 gene expression in broiler quails. Three hundred and fifty (one days-old) quails were allotted to seven dietary treatments with five replicates as an experimental randomized design study. Treatments were basal diet as a control, control +100 and +200 mg of vitamin E, sesamin and thymoquinone per each kg of diet resp...
Source: Animal Biotechnology - September 20, 2023 Category: Biotechnology Authors: Yaser Rahimian Farshid Kheiri Mostafa Faghani Source Type: research

Fight Aging! Newsletter, August 14th 2023
This study demonstrates just how vital the thymus is to maintaining adult health." « Back to Top Does Amyloid-β Aggregation Cause Broad Disruption of Proteostasis? https://www.fightaging.org/archives/2023/08/does-amyloid-%ce%b2-aggregation-cause-broad-disruption-of-proteostasis/ Researchers here speculate on the ability of insoluble amyloid-β aggregates to be broadly disruptive of the solubility of many other proteins, and thus disruptive to cell and tissue function. Is this important in aging? The evidence here shows the existence of the mechanism in a lower species, but that doesn't n...
Source: Fight Aging! - August 13, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, June 19th 2023
In conclusion, among Swedish middle-aged subjects, nearly two-thirds showed complete fatty degeneration of thymus on CT. Age-Related Dysfunction of Water Homeostasis https://www.fightaging.org/archives/2023/06/age-related-dysfunction-of-water-homeostasis/ Dehydration can be an issue in older people. As in every complex system in the body, the mechanisms by which hydration is regulated become dysfunctional with advancing age. Researchers here look at the brain region responsible for regulating some of the response to dehydration, cataloging altered gene expression in search of the more important mechani...
Source: Fight Aging! - June 18, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, January 16th 2023
Conclusions Implanted Hair Follicle Cells Produce Remodeling of Scar Tissue Assessment of Somatic Mosaicism as a Biomarker of Aging The Gut Microbiome of Centenarians https://www.fightaging.org/archives/2023/01/the-gut-microbiome-of-centenarians/ The state of the gut microbiome is arguably as influential on health as exercise. Various microbial species present in the gut produce beneficial metabolites, such as butyrate, or harmful metabolites, such as isoamylamine, or can provoke chronic inflammation in a variety of ways. An individual can have a better or worse microbiome, assessing these and other fu...
Source: Fight Aging! - January 15, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, May 23rd 2022
In conclusion, remofuscin activates the lysosome-to-nucleus pathway in C. elegans, thereby increasing the expression levels of xenobiotic detoxification genes resulted in extending their lifespan. Naked Mole-Rat Skin Shows Fewer Signs of Aging https://www.fightaging.org/archives/2022/05/naked-mole-rat-skin-shows-fewer-signs-of-aging/ Naked mole-rats exhibit a maximum life span that is many times longer than is the case for similarly sized mammals. Further, they are negligibly senescent, showing few age-related declines in function across much of that lengthy life span. That includes maintenance of stem c...
Source: Fight Aging! - May 22, 2022 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

SHEDDING LIGHT ON THE TOXICITY OF SARS-CoV-2-DERIVED PEPTIDE IN NON-TARGET COVID-19 ORGANISMS: A STUDY INVOLVING INBRED AND OUTBRED MICE
Neurotoxicology. 2022 Apr 5:S0161-813X(22)00048-1. doi: 10.1016/j.neuro.2022.03.012. Online ahead of print.ABSTRACTDespite advances in research on the vaccine and therapeutic strategies of COVID-19, little attention has been paid to the possible (eco)toxicological impacts of the dispersion of SARS-CoV-2 particles in natural environments. Thus, in this study, we aimed to evaluate the behavioral and biochemical consequences of the short exposure of outbred and inbred mice (male Swiss and C57Bl/6J mice, respectively) to PSPD-2002 (peptide fragments of the Spike protein of SARS-CoV-2) synthesized in the laboratory. Our data de...
Source: Neurotoxicology - April 8, 2022 Category: Neurology Authors: Thiarlen Marinho da Luz Amanda Pereira da Costa Ara újo Fernanda Neves Estr êla Rezende Abner Marcelino Silva Ives Charlie-Silva Helyson Lucas Bezerra Braz Paulo R S Sanches Md Mostafizur Rahman Dami à Barceló Guilherme Malafaia Source Type: research

Dietary carob fruit (Ceratonia siliqua L.) supplementation improves spermatogenesis, semen quality and embryonic death via antioxidant effect in aging broiler breeder roosters
In conclusion, CF supplementation in aging roosters' diet enhanced the sperm motility, seminal and blood antioxidant capacity, and testicular spermatogenenic indexes.PMID:35299115 | DOI:10.1016/j.anireprosci.2022.106967
Source: Animal Reproduction Science - March 17, 2022 Category: Zoology Authors: Zabihollah Nemati Parviz Dehgani Maghsoud Besharati Saeid Amirdahri Source Type: research

Quercetin ameliorates ochratoxin A-Induced immunotoxicity in broiler chickens by modulation of PI3K/AKT pathway
Chem Biol Interact. 2021 Oct 27:109720. doi: 10.1016/j.cbi.2021.109720. Online ahead of print.ABSTRACTOchratoxin A (OTA) is a fungal secondary metabolite produced by certain species of Aspergillus and Penicillium, and exerts immunosuppressive effect on humans and animals. Quercetin (QUE) is one of the flavonoids produced as a plant-secondary metabolite. The present study was designed to evaluate the efficacy of QUE against the immunotoxic hazard of OTA in broiler chickens. Forty one-day-old broiler chicks were randomly and equally allocated into four groups; control, OTA (0.5 mg/kg feed), QUE (0.5 g/kg feed) and OTA + QUE ...
Source: Chemico-Biological Interactions - October 31, 2021 Category: Molecular Biology Authors: Rehab E Abdelrahman Abdel Azeim A Khalaf Mohamed A Elhady Marwa A Ibrahim Eman I Hassanen Peter A Noshy Source Type: research

Pages: 1  2  3