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Total 113 results found since Jan 2013.
Omega-3 nanoemulgel in prevention of radiation-induced oral mucositis and its associated effect on microbiome: a randomized clinical trial
CONCLUSIONS: Topical Omega-3 nanoemulgel demonstrated a beneficial effect in prevention of radiation-induced oral mucositis with a possibility of regulating oral microbial dysbiosis.PMID:37648997 | DOI:10.1186/s12903-023-03276-5
Source: Cancer Control - August 30, 2023 Category: Cancer & Oncology Authors: Basma M Morsy Shahira El Domiaty Mohamed A M Meheissen Lamia A Heikal Marwa A Meheissen Nourhan M Aly Source Type: research
Fight Aging! Newsletter, June 12th 2023
In this study, we investigated the effect of NXP032 on neurovascular stabilization through the changes of PECAM-1, PDGFR-β, ZO-1, laminin, and glial cells involved in maintaining the integrity of the blood-brain barrier (BBB) in aged mice. NXP032 was orally administered daily for 8 weeks. Compared to young mice and NXP032-treated mice, 20-month-old mice displayed cognitive impairments in Y-maze and passive avoidance tests. NXP032 treatment contributed to reducing the BBB damage by attenuating the fragmentation of microvessels and reducing PDGFR-β, ZO-1, and laminin expression, thereby mitigating astrocytes and microglia ...
Source: Fight Aging! - June 11, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Candidate SNP Markers Significantly Altering the Affinity of TATA-Binding Protein for the Promoters of Human Hub Genes for Atherogenesis, Atherosclerosis and Atheroprotection
Int J Mol Sci. 2023 May 19;24(10):9010. doi: 10.3390/ijms24109010.ABSTRACTAtherosclerosis is a systemic disease in which focal lesions in arteries promote the build-up of lipoproteins and cholesterol they are transporting. The development of atheroma (atherogenesis) narrows blood vessels, reduces the blood supply and leads to cardiovascular diseases. According to the World Health Organization (WHO), cardiovascular diseases are the leading cause of death, which has been especially boosted since the COVID-19 pandemic. There is a variety of contributors to atherosclerosis, including lifestyle factors and genetic predispositio...
Source: Atherosclerosis - May 27, 2023 Category: Cardiology Authors: Anton Bogomolov Sergey Filonov Irina Chadaeva Dmitry Rasskazov Bato Khandaev Karina Zolotareva Anna Kazachek Dmitry Oshchepkov Vladimir A Ivanisenko Pavel Demenkov Nikolay Podkolodnyy Ekaterina Kondratyuk Petr Ponomarenko Olga Podkolodnaya Zakhar Mustafin Source Type: research
Utilization of Marine Seaweeds as a Promising Defense Against COVID-19: a Mini-review
Mar Biotechnol (NY). 2023 May 27. doi: 10.1007/s10126-023-10214-7. Online ahead of print.ABSTRACTCOVID-19 is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which mainly affects the respiratory system. It has been declared as a "pandemic" in March 2020 by the World Health Organization due to the high spreading rate. SARS-CoV-2 binds with the angiotensin-converting enzyme 2 (ACE2) receptors on the cell surface which leads to the downregulation of ACE2 and upregulation of angiotensin-converting enzyme (ACE) receptors. The elevated level of cytokines and ACE receptors leads to the ...
Source: Marine Biotechnology - May 27, 2023 Category: Biotechnology Authors: M D T L Gunathilaka Source Type: research
Candidate SNP Markers Significantly Altering the Affinity of TATA-Binding Protein for the Promoters of Human Hub Genes for Atherogenesis, Atherosclerosis and Atheroprotection
Int J Mol Sci. 2023 May 19;24(10):9010. doi: 10.3390/ijms24109010.ABSTRACTAtherosclerosis is a systemic disease in which focal lesions in arteries promote the build-up of lipoproteins and cholesterol they are transporting. The development of atheroma (atherogenesis) narrows blood vessels, reduces the blood supply and leads to cardiovascular diseases. According to the World Health Organization (WHO), cardiovascular diseases are the leading cause of death, which has been especially boosted since the COVID-19 pandemic. There is a variety of contributors to atherosclerosis, including lifestyle factors and genetic predispositio...
Source: Atherosclerosis - May 27, 2023 Category: Cardiology Authors: Anton Bogomolov Sergey Filonov Irina Chadaeva Dmitry Rasskazov Bato Khandaev Karina Zolotareva Anna Kazachek Dmitry Oshchepkov Vladimir A Ivanisenko Pavel Demenkov Nikolay Podkolodnyy Ekaterina Kondratyuk Petr Ponomarenko Olga Podkolodnaya Zakhar Mustafin Source Type: research
Utilization of Marine Seaweeds as a Promising Defense Against COVID-19: a Mini-review
Mar Biotechnol (NY). 2023 May 27. doi: 10.1007/s10126-023-10214-7. Online ahead of print.ABSTRACTCOVID-19 is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which mainly affects the respiratory system. It has been declared as a "pandemic" in March 2020 by the World Health Organization due to the high spreading rate. SARS-CoV-2 binds with the angiotensin-converting enzyme 2 (ACE2) receptors on the cell surface which leads to the downregulation of ACE2 and upregulation of angiotensin-converting enzyme (ACE) receptors. The elevated level of cytokines and ACE receptors leads to the ...
Source: Marine Biotechnology - May 27, 2023 Category: Biotechnology Authors: M D T L Gunathilaka Source Type: research
Potential Of Angiotensin-(1-7) In Covid-19 Treatment
Curr Protein Pept Sci. 2022 Nov 30. doi: 10.2174/1389203724666221130140416. Online ahead of print.ABSTRACTThe new coronavirus currently named SARS-CoV-2 was announced by the World Health Organization as the virus causing the COVID-19 pandemic. The pathogenesis of SARS-CoV-2 initiates upon contact of a structural spike protein with the angiotensin II-converting enzyme receptor, leading to the induction of inflammatory mechanisms and progression to severe disease in some cases. Currently, studies have emerged linking COVID-19 with angiotensin-(1-7), demonstrating the potential of angiotensin-(1-7)/Mas Receptor axis induction...
Source: Current Protein and Peptide Science - December 1, 2022 Category: Biochemistry Authors: Patricia Luna Mar ía Fernanda Pérez Jairo Castellar Aileen Chang Yuliet Montoya John Bustamante Wendy Rosales Rada Evelyn Mendoza-Torres Source Type: research
Pathophysiological Abnormalities in Migraine Ameliorated by Ketosis: A Proof-of-Concept Review
J Integr Neurosci. 2022 Oct 11;21(6):167. doi: 10.31083/j.jin2106167.ABSTRACTMigraine is a prevalent heterogeneous neurological disorder, enumerated as the eighth most disabling neurological disorder by the World Health Organization. The growing advancement in technology and investigation of various facets of cerebral metabolism in migraine has shed light to metabolic mechanisms in migraine pathophysiology. A growing number of clinical research postulates migraine as a reaction to oxidative stress levels that go beyond antioxidant capacity or cerebral energy deficiency. This has become an extremely attractive subject area ...
Source: Journal of Integrative Neuroscience - November 25, 2022 Category: Neuroscience Authors: Panitda Huynh Pasquale Calabrese Source Type: research
