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Merck locates frozen batch of undisclosed Ebola vaccine, will donate for testing in Uganda ’s outbreak
In a revelation that may help Uganda combat its outbreak of Ebola, the pharmaceutical giant Merck has acknowledged to Science— after repeated inquiries — that it has up to 100,000 doses of an experimental vaccine for the deadly viral disease in its freezers in Pennsylvania and will donate them. The World Health Organization (WHO) and the Ugandan government are discussing if and how these doses can be incorporated into one or more clinical trials of other candidate Ebola vaccines that could launch as soon as next month. The Merck vaccine targets Sudan ebolavirus, the pathogen currently circulating...
Source: ScienceNOW - October 23, 2022 Category: Science Source Type: news

TWiV 939: From lizards to Lassa with Tom Monath
Tom Monath joins TWiV to discuss his wide-ranging career that includes medicine, field work and vaccine development while working for the US government, the US military, and multiple biotechnology companies. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit Guest: Tom Monath Click arrow to playDownload TWiV 939 (73 MB .mp3, 121 min)Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email […]
Source: virology blog - September 25, 2022 Category: Virology Authors: Vincent Racaniello Tags: This Week in Virology Acambis COVID-19 dengue vaccine ebola virus Lassa virus NewLink Genetics vaccine platform viral viruses yellow fever virus Source Type: blogs

The Evolution of Medical Countermeasures for Ebola Virus Disease: Lessons Learned and Next Steps
Vaccines (Basel). 2022 Jul 29;10(8):1213. doi: 10.3390/vaccines10081213.ABSTRACTThe Ebola virus disease outbreak that occurred in Western Africa from 2013-2016, and subsequent smaller but increasingly frequent outbreaks of Ebola virus disease in recent years, spurred an unprecedented effort to develop and deploy effective vaccines, therapeutics, and diagnostics. This effort led to the U.S. regulatory approval of a diagnostic test, two vaccines, and two therapeutics for Ebola virus disease indications. Moreover, the establishment of fieldable diagnostic tests improved the speed with which patients can be diagnosed and publi...
Source: Cancer Control - August 26, 2022 Category: Cancer & Oncology Authors: Ian Crozier Kyla A Britson Daniel N Wolfe John D Klena Lisa E Hensley John S Lee Larry A Wolfraim Kimberly L Taylor Elizabeth S Higgs Joel M Montgomery Karen A Martins Source Type: research

He battled AIDS, COVID-19, and Trump. Now, Anthony Fauci is stepping down
Anthony Fauci, the renowned physician-scientist who has led the $6.3 billion National Institute of Allergy and Infectious Diseases (NIAID) for nearly 4 decades and since early 2020 has been the U.S. government’s voice of scientific reason during the COVID-19 pandemic, will step down from government service in December. Fauci, 81, had said in recent interviews that he planned to retire from the government by the end of President Joe Biden’s administration, but did not give a date until today. He said in a statement that although leading NIAID “has been the honor of a lifetime,” he plans to “pursue...
Source: Science of Aging Knowledge Environment - August 22, 2022 Category: Geriatrics Source Type: research

The Virus Hunters Trying to Prevent the Next Pandemic
Nobody saw SARS-CoV-2 coming. In the early days of the pandemic, researchers were scrambling to collect samples from people who had mysteriously developed fevers, coughs, and breathing problems. Pretty soon, they realized that the disease-causing culprit was a new virus humans hadn’t seen before. And the world, lacking a coordinated global response, was unprepared. Some countries acted quickly to develop tests for the novel coronavirus, while others with fewer resources were left behind. With a virus oblivious to national borders, and with travel between countries and continents more common than it had been in previo...
Source: TIME: Health - August 1, 2022 Category: Consumer Health News Authors: Alice Park and Video by Andrew D. Johnson Tags: Uncategorized Disease Frontiers of Medicine 2022 healthscienceclimate Source Type: news

Inside the Global Quest to Trace the Origins of COVID-19 —and Predict Where It Will Go Next
It wasn’t greed, or curiosity, that made Li Rusheng grab his shotgun and enter Shitou Cave. It was about survival. During Mao-era collectivization of the early 1970s, food was so scarce in the emerald valleys of southwestern China’s Yunnan province that farmers like Li could expect to eat meat only once a year–if they were lucky. So, craving protein, Li and his friends would sneak into the cave to hunt the creatures they could hear squeaking and fluttering inside: bats. Li would creep into the gloom and fire blindly at the vaulted ceiling, picking up any quarry that fell to the ground, while his companion...
Source: TIME: Health - July 23, 2020 Category: Consumer Health News Authors: Charlie Campbell/ Yuxi, Yunnan and Alice Park Tags: Uncategorized COVID-19 feature Magazine Source Type: news

Neglected Diseases Kill More People than COVID-19 – It’s Time to Address Them
Credit: UNBy Ifeanyi Nsofor and Adaeze OrehABUJA, Mar 30 2020 (IPS) As COVID-19 surges globally and leaves fear and panic in its wake, global efforts are underway to find a cure. Yet, the same level of response is lacking for several other infectious diseases that kill millions annually. These kinds of neglected tropical diseases (NTDs) are a broad group of communicable diseases which affect more than two billion people and cost developing economies billions of dollars every year. Lassa Fever is an example and is endemic in Nigeria and other West African countries such as Benin, Ghana, Guinea, Liberia, Mali and Sierra ...
Source: IPS Inter Press Service - Health - March 30, 2020 Category: International Medicine & Public Health Authors: Ifeanyi Nsofor and Adaeze Oreh Tags: Global Headlines Health TerraViva United Nations Neglected Tropical Diseases (NTDs) Source Type: news

Digital Health And The Ebola Epidemic: How Not To Let It Go Viral
More than 1,500 deaths and 2,500 people sickened – that’s the recent account of the ebola outbreak in the Democratic Republic of Congo (DRC) raging in the country since last August, and recently declared a public health emergency of international concern. Experts say efforts to contain the virus are hindered by biological, public health, political, and cultural issues, but we looked around what digital health technologies could do to mitigate the spread and the devastation of the infectious disease. The Spaghetti-like virus… The lethal Ebola virus first appeared in 1976 around a river in Congo – it was named ...
Source: The Medical Futurist - August 1, 2019 Category: Information Technology Authors: nora Tags: Future of Medicine Africa AI artificial intelligence Congo digital digital health digital maps disease disease outbreak ebola epidemic Innovation technology Source Type: blogs

TWiV 533: Recurring threads
The TWiVosophers review the Chinese plasma virome revealed by non-invasive prenatal testing, and a new filovirus genome from bats in China. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ASV 2019 European Congress of Virology 2019 ASM Clinical Virology Symposium Intel ISEF judges needed Jerard Hurwitz age 90 RIP Paul has Measles now in French (virology blog) Chinese plasma virome (Cell) Blood virome of 8000 humans (TWiV 435) Měnglà filovirus from bats in China (Nat Microbiol) How to w...
Source: This Week in Virology - MP3 Edition - February 3, 2019 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Top 12 Global Health Moments of 2018
By The Editorial Team, IntraHealth InternationalDecember 14, 2018A month-by-month guide to the moments that captivated us most throughout the year.As 2018 comes to an end, we ’re looking back on the moments this year that filled us with joy, wonder, sorrow, and fear.These are some of the ones we won ’t forget:January: A mother and daughter assassinated in Pakistan for delivering polio vaccinesThis was the year we were supposed to eradicate polio, according to thePolio Eradication and Endgame Strategic Plan 2013 –2018. But there were27 new cases of wild poliovirus this year and it remains endemic in Afghanistan, Pak...
Source: IntraHealth International - December 14, 2018 Category: International Medicine & Public Health Authors: mnathe Tags: Capacity Building for Fistula Treatment and Prevention in Mali (Fistula Mali) Family Planning & Reproductive Health Infectious Diseases Ebola obstetric fistula technology Policy Advocacy Health Workforce Systems Primary Health Care Source Type: news

Philanthropists Join Forces to Fund Africa ’s Cash-Strapped Health Sector
Tristate Heart and Vascular Centre in Nigeria. Credit: Tristate Heart and Vascular CentreBy Pavithra Rao, Africa Renewal*NEW YORK, Sep 28 2017 (IPS)In the 2017 World Happiness Report by Gallup, African countries score poorly. Of the 150 countries on the list, the Central African Republic, Tanzania and Burundi rank as the unhappiest countries in the world. Some of the factors driving unhappiness are the poor state of the continent’s health care systems, the persistence of HIV/AIDS, malaria and tuberculosis, and the growth of lifestyle diseases such as hypertension, heart disease and diabetes.Few African countries make sig...
Source: IPS Inter Press Service - Health - September 28, 2017 Category: International Medicine & Public Health Authors: Pavithra Rao Tags: Development & Aid Featured Global Headlines Health TerraViva United Nations Source Type: news

Why Doctors should read books by Nassim Taleb
By SAURABH JHA, MD     “There are some enterprises in which a careful disorderliness is the true method” Herman Melville, Moby Dick Asymmetry of Error During the Ebola epidemic calls to ban flights from Africa from some quarters were met by accusations of racism from other quarters. Experts claimed that Americans were at greater risk of dying from cancer than Ebola, and if they must fret they should fret more about cancer than Ebola. One expert, with a straight Gaussian face, went as far as saying that even hospitals were more dangerous than Ebola. Pop science reached an unprecedented fizz. Trader and mathem...
Source: The Health Care Blog - September 12, 2017 Category: Consumer Health News Authors: at RogueRad Tags: Economics The Business of Health Care Source Type: blogs

Why Doctors (And Everybody Else) Should Read Books by Nassim Taleb
By SAURABH JHA, MD “There are some enterprises in which a careful disorderliness is the true method” – Herman Melville, Moby Dick Asymmetry of Error During the Ebola epidemic calls to ban flights from Africa from some quarters were met by accusations of racism from other quarters. Experts claimed that Americans were at greater risk of dying from cancer than Ebola, and if they must fret they should fret more about cancer than Ebola. One expert, with a straight Gaussian face, went as far as saying that even hospitals were more dangerous than Ebola. Pop science reached an unprecedented fizz. Trader and mathematicia...
Source: The Health Care Blog - September 12, 2017 Category: Consumer Health News Authors: at RogueRad Tags: Economics The Business of Health Care Source Type: blogs

Research Using Fetal Tissue
Hello HuffPo! Some of you may know me from junkscience.com or healthnewsdigest.com. My main focus here will be on science, or what passes for science these days. Many people of good will are not aware that our government spends more than $400 billion per year on R & D. Regrettably, a substantial amount of that ends of being little more than a form of academic welfare, for research that has almost no chance of ever leading to anything practical, and in many cases does not even add to so-called "basic knowledge." By way of example (and I will have many more), let's take a look at a current hot topic: Research using fetal tis...
Source: Science - The Huffington Post - September 1, 2015 Category: Science Source Type: news

Innovations in Science: The Cuban Research Connection
On July 20, 2015 the governments of the United States and Cuba officially re-established diplomatic ties by opening embassies in Washington DC and Havana, after a 55 year embargo initiated by the Kennedy Administration in 1960. The full impact of US re-engagement with Cuba has yet to be determined, but two business sectors have been quick to take advantage of this nascent relationship: travel and academia. While there are still travel restrictions between the two countries, direct US to Cuba flights are already being offered through JetBlue and others will no doubt follow suit, as will the major hotel chains. It's also go...
Source: Science - The Huffington Post - August 26, 2015 Category: Science Source Type: news