Research Using Fetal Tissue

Hello HuffPo! Some of you may know me from junkscience.com or healthnewsdigest.com. My main focus here will be on science, or what passes for science these days. Many people of good will are not aware that our government spends more than $400 billion per year on R &D. Regrettably, a substantial amount of that ends of being little more than a form of academic welfare, for research that has almost no chance of ever leading to anything practical, and in many cases does not even add to so-called "basic knowledge." By way of example (and I will have many more), let's take a look at a current hot topic: Research using fetal tissue. This is hardly a new phenomenon. Fetal tissue has been harvested for medical research for years. Even before abortion was legalized, other sources were tapped, and according to an article by AP science writer Malcolm Ritter, this practice dates back to the 1930s. Ritter, and many others, like to invoke the 1954 Nobel Prize for Physiology or Medicine. As Ritter puts it, "The 1954 Nobel Prize in medicine was awarded for work with fetal tissue that led to developing a vaccine against polio." Not so fast... According to the Nobel Foundation, that particular prize was awarded jointly to John Franklin Enders, Thomas Huckle Weller, and Frederick Chapman Robbins "for their discovery of the ability of poliomyelitis viruses to grow in cultures of various types of tissue." Indeed, many types of tissue were used besides human embryo...
Source: Science - The Huffington Post - Category: Science Source Type: news

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Authors: Kim SE, Lee SJ, Cha JY, Yi SW, Kim TS, Cho IL, Kwak JY, Oh KH Abstract Colon cancer is very rarely accompanied by tumor thrombosis of the superior mesenteric vein (SMV). A 46-year-old patient had been diagnosed with SMV tumor thrombosis related to colon cancer without hepatic metastasis and underwent right hemicolectomy with SMV tumor thrombectomy. Tumor thrombosis was pathologically confirmed as metastatic colon cancer. There has been no recurrence for 12 months with 12 cycles of adjuvant-chemotherapy. PMID: 30992420 [PubMed - as supplied by publisher]
Source: Clinical Endoscopy - Category: Gastroenterology Tags: Clin Endosc Source Type: research
Publication date: Available online 18 April 2019Source: Pathology - Research and PracticeAuthor(s): Xiao-Jie Chen, Ya-Qin Tan, Na Zhang, Ming-Jing He, Gang ZhouAbstractObjectiveIn recent years, monoclonal antibodies targeting programmed cell death-ligand 1 (PD-L1) have become a promising cancer immunotherapy. However, the role of PD-L1 in oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMDs), including oral leukoplakia (OLK), remains controversial. The aim of the present study was to investigate the expression level of PD-L1 in OSCC and OPMDs, and examine its relationship with CD8 expression ...
Source: Pathology Research and Practice - Category: Pathology Source Type: research
In conclusion, our findings indicate that targeting miR-142-5p may provide a novel strategy for the treatment of pancreatic cancer.
Source: Pathology Research and Practice - Category: Pathology Source Type: research
Conclusions: Our study demonstrated that TRIP13 might be a tumor promoting factor in ESCC and a promising prognostic indicator for ESCC patient.
Source: Pathology Research and Practice - Category: Pathology Source Type: research
In conclusion, B7-H3 could be a target of bone cancers.
Source: Pathology Research and Practice - Category: Pathology Source Type: research
ConclusionCircRNAs have high sensitivity and specificity in the diagnosis of gastric cancer, and it may become an auxiliary diagnostic biomarker of gastric cancer.
Source: Pathology Research and Practice - Category: Pathology Source Type: research
This study aimed to investigate the role and regulatory mechanism of CypB in NSCLC progression. The expression levels of CypB was detected in NSCLC samples and cell lines by ELISA, western blot and immunohistochemistry assay. In addition, CCK8, colony formation, scratch and transwell assays were used to evaluate the proliferation, migration and invasion of A549 cells with CypB silencing. The expression of angiogenesis related proteins and pathway-related factors were detected by western blot. In NSCLC samples, CypB expression was upregulated. The expression of CypB was significantly reduced in the siRNA-cyclophilin B group...
Source: Pathology Research and Practice - Category: Pathology Source Type: research
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
Conclusion The use of specific mobile applications should be en couraged to attain a better quality and accuracy in prescriptions and to include strategies that not only reduce the risk of negative outcomes, but also improve the quality of care and treatment for maintaining the health both of the mother and of the baby.Resumo Objetivo Analisar a prescri ção de antimicrobianos para gestantes admitidas no serviço de obstetrícia que apresentaram pielonefrite aguda. Métodos Foram realizados três estudos transversais comparando a prescrição de antimicrobianos para pielonefr...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
Publication date: Available online 17 April 2019Source: Gynecologic Oncology ReportsAuthor(s): Dimitrios Nasioudis, Emily M. Ko, Ashley F. Haggerty, Robert Giuntoli, Robert Burger, Mark A. Morgan, Nawar A. LatifAbstractObjectiveThe aim of the present study is to investigate the patterns of use and prognostic significance of adjuvant chemotherapy (CT) for patients with stage IC ovarian granulosa cell tumors (GCTs).MethodsWe identified patients with stage IC GCTs diagnosed between 2004 and 2015 in the National Cancer Data Base (NCDB). Logistic regression was performed to identify variables independently associated with chemo...
Source: Gynecologic Oncology Reports - Category: OBGYN Source Type: research
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