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Management: Hospitals
Nutrition: Probiotics
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Total 669 results found since Jan 2013.
Understanding mechanisms of virulence in MRSA: implications for anti-virulence treatment strategies
Expert Rev Anti Infect Ther. 2023 Jul 27. doi: 10.1080/14787210.2023.2242585. Online ahead of print.ABSTRACTINTRODUCTION: Methicillin-resistant Staphylococcus aureus (MRSA) is a widespread pathogen, often causing recurrent and deadly infections in the hospital and community. Many S. aureus virulence factors have been suggested as potential targets for antivirulence therapy to decrease the threat of diminishing antibiotic availability. Antivirulence methods hold promise due to their adjunctive and prophylactic potential and decreased risk for selective pressure.AREAS COVERED: This review describes the dominant virulence mec...
Source: Expert Review of Anti-Infective Therapy - July 28, 2023 Category: Infectious Diseases Authors: Roger C Hsieh Ryan Liu Dylan J Burgin Michael Otto Source Type: research
How to reduce the colorectal anastomotic leakage? The MIRACLe protocol experience in a cohort in a single high-volume centre
This article reports the results of a novel perioperative treatment implementing the gut microbiota to prevent anastomotic fistula and leakage (AL) in patients undergoing laparoscopic colorectal resections for cancer and represents the continuation of our pilot study on 60 cases. A series of 131 patients underwent elective colorectal surgery at the S. Eugenio Hospital (Rome-Italy) between December 1, 2020, and November 30, 2022, and received a perioperative preparation following the Microbiota Implementation to Reduce Anastomotic Colorectal Leaks (MIRACLe) protocol comprising oral antibiotics, mechanical bowel preparation ...
Source: Cancer Control - July 15, 2023 Category: Cancer & Oncology Authors: Rosa Marcellinaro Michele Grieco Domenico Spoletini Raffaele Troiano Pasquale Avella Gioia Brachini Andrea Mingoli Massimo Carlini Source Type: research
Oral konjac glucomannan for prevention of ionizing radiation-induced injury by regulating gut microbiota and increasing short chain fatty acids
Int J Biol Macromol. 2023 Apr 10:124402. doi: 10.1016/j.ijbiomac.2023.124402. Online ahead of print.ABSTRACTIonizing radiation-induced injury commonly happens in radiotherapy, leading to damages of the hematopoietic and gastrointestinal systems. Radioprotective medications are mainly applied in hospitals, although only injections are available and their gut protection is limited. Here, oral konjac glucomannan (KGM), a natural macromolecule and soluble dietary fiber, was used against ionizing radiation-induced injury. The mice were fed with KGM (0.4 g/kg) for 3 days or injected with a clinical medication amifostine before 6...
Source: International Journal of Biological Macromolecules - April 12, 2023 Category: Biochemistry Authors: Dongdong Liu Bo Zhuang Meng Wei Tianyu Yuan Jian Li Pei Deng Lina Du Bochuan Yuan Yiguang Jin Source Type: research
Bifidobacterium bacteraemia is rare with routine probiotics use in preterm infants: A further case report with literature review
Anaerobe. 2023 Feb 6:102713. doi: 10.1016/j.anaerobe.2023.102713. Online ahead of print.ABSTRACTProphylactic administration of oral probiotics is associated with significant reductions in the morbidity and mortality of necrotising enterocolitis in preterm infants. We document the first case of Bifidobacterium longum subsp. infantis sub-clinical bacteraemia, in an extremely low birth weight preterm infant, since introduction of routine probiotic treatment at the Norfolk and Norwich University Hospital 10 years ago. Whole genome comparisons confirmed the isolated strain likely originated from the probiotic product.PMID:36754...
Source: Anaerobe - February 8, 2023 Category: Microbiology Authors: Antia Acuna-Gonzalez Magdalena Kujawska Mayada Youssif Thomas Atkinson Sara Grundy Alexandra Hutchison Catherine Tremlett Paul Clarke Lindsay J Hall Source Type: research
Rectal stimulation with prebiotics and probiotics before ileostomy reversal: a study protocol for a randomized controlled trial
This study is registered in the Brazilian Trial Registry (ReBEC) under RBR-366n64w. Registration date: 19/07/2022.PMID:36647079 | DOI:10.1186/s13063-023-07065-x
Source: Cancer Control - January 16, 2023 Category: Cancer & Oncology Authors: Mar ília Marcelino Francisco Tustumi Lucas Soares Gerbasi Rafael Vaz Pandini Rafaela de Souza Novo Marleny Novaes Figueiredo de Araujo Elis Oliveira Victor Edmond Seid Sergio Eduardo Alonso Araujo Source Type: research
Breast microecology improvement using probiotics following needle aspiration in patients with lactational breast abscess: a multi-center randomized double-blind controlled trial
This study was registered in the Chinese Clinical Trial Registry ( http://www.chictr.org.cn ), registration number: ChiCTR2000032682, registration date: 6/May/ 2020; first entry date: 11/May/2020.PMID:36202884 | DOI:10.1038/s41598-022-20756-w
Source: Cancer Control - October 6, 2022 Category: Cancer & Oncology Authors: Yi Zhang Yajun Gao Jing Qin Xiaoting Li Fei Jiang Yuanxuan Cai Hui Feng Xidong Gu Mingze Gao Lijuan Wang Yiqi Lin Yingyi Fan Bucun Xu Enli Wang Qing Shao Source Type: research
Bacterial hydrophilins promote pathogen desiccation tolerance
Cell Host Microbe. 2022 Apr 5:S1931-3128(22)00149-4. doi: 10.1016/j.chom.2022.03.019. Online ahead of print.ABSTRACTAcinetobacter baumannii is a leading cause of hospital-acquired infections, where outbreaks are driven by its ability to persist on surfaces in a desiccated state. Here, we show that A. baumannii causes more virulent pneumonia following desiccation and profile the genetic requirements for desiccation. We find that desiccation tolerance is enhanced upon the disruption of Lon protease, which targets unfolded and aggregated proteins for degradation. Notably, two bacterial hydrophilins, DtpA and DtpB, are transcr...
Source: Cell Host and Microbe - April 12, 2022 Category: Microbiology Authors: Erin R Green Joseph N Fakhoury Andrew J Monteith Hualiang Pi David P Giedroc Eric P Skaar Source Type: research
Lactobacillus spp. derived biosurfactants effect on expression of genes involved in Proteus mirabilis biofilm formation
In this study we showed that biosurfacant treatment can pave the way for a possible control of biofilm development. Based on our findings, we suggest that the prepared biosurfactant may interfere with adhesion of P. mirabilis to catheters and other devices.PMID:35272045 | DOI:10.1016/j.meegid.2022.105264
Source: Infection, Genetics and Evolution - March 10, 2022 Category: Genetics & Stem Cells Authors: Shokouhfard Maliheh Kermanshahi R-Kasra Feizabadi M-Mehdi Teimourian Shahram Safari Fatemeh Source Type: research
