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Vaccination: Veterinary Vaccinations
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Total 39 results found since Jan 2013.
Vaccines for prion diseases: a realistic goal?
Cell Tissue Res. 2023 Feb 11. doi: 10.1007/s00441-023-03749-7. Online ahead of print.ABSTRACTPrion diseases are fatal infectious neurodegenerative disorders and prototypic conformational diseases, caused by the conformational conversion of the normal cellular prion protein (PrPC) into the pathological PrPSc isoform. Examples are scrapie in sheep and goat, bovine spongiform encephalopathy (BSE) in cattle, chronic wasting disease (CWD) in cervids, and Creutzfeldt-Jacob disease (CJD) in humans. There are no therapies available, and animal prion diseases like BSE and CWD can negatively affect the economy, ecology, animal healt...
Source: Cell Research - February 10, 2023 Category: Cytology Authors: Scott Napper Hermann M Schatzl Source Type: research
Isolation and Identification of Novel Highly Pathogenic Avian Influenza Virus (H5N8) Subclade 2.3.4.4b from Geese in Northeastern China
Appl Environ Microbiol. 2023 Jan 5:e0157222. doi: 10.1128/aem.01572-22. Online ahead of print.ABSTRACTH5N8, a highly pathogenic avian influenza, has become a new zoonotic threat in recent years. As of December 28, 2021, at least 3,206 H5N8 cases had been reported in wild birds and poultry worldwide. In January 2021, a novel virus strain named A/goose/China/1/2021 was isolated during an H5N8 goose influenza outbreak in northeastern China. The PB2, PB1, HA, and M genes of A/goose/China/1/2021 were highly identical to those of H5N8 strains emerging in Kazakhstan and Russia in Central Asia from August to September 2020, while ...
Source: Applied and Environmental Microbiology - January 5, 2023 Category: Microbiology Authors: Yanting Zhu Yulin Cong Yixue Sun Jinhong Han Lili Gai Tiantian Yang Chang Liu Lifeng Zhao Yanlong Cong Source Type: research
Efficient rescue of a newly classified Ebinur lake orthobunyavirus with GFP reporter and its application in rapid antiviral screening
Antiviral Res. 2022 Sep 20:105421. doi: 10.1016/j.antiviral.2022.105421. Online ahead of print.ABSTRACTOrthobunyaviruses have been reported to cause severe diseases in humans or animals, posing a potential threat to human health and socio-economy. Ebinur lake virus (EBIV) is a newly classified orthobunyavirus, which can induce the histopathogenic change and even the high mortality of infected BALB/c mice. Therefore, it is needed to further study the viral replication and pathogenesis, and develop the therapies to cope with its potential infection to human or animals. Here, through the reverse genetics system, the recombina...
Source: Antiviral Research - September 23, 2022 Category: Virology Authors: Nanjie Ren Fei Wang Lu Zhao Shunlong Wang Guilin Zhang Jiaqi Li Bo Zhang Jinglin Wang Eric Bergeron Zhiming Yuan Han Xia Source Type: research
The Macro View – Health, Economics, and Politics and the Big Picture. What I Am Watching Here And Abroad.
August 04, 2022 Edition-----The war seems to grind on sadly and Pres. Biden is having a second round with COVID as unprecedented weather happens all over the US. It all feels rather like ‘the end of days’!In the UK we see an increasing chance of a third female PM being elected as the country seems to be struggling. We do need to remember however the UK remains a significant power with nuclear weapons and home-grown nuclear submarines!In OZ we have had last week working out how to progress the First Nations ‘Voice’ as we wrap up the 1st session of Parliament for the new Government. Comments welcome on how you think ...
Source: Australian Health Information Technology - August 4, 2022 Category: Information Technology Authors: Dr David G More MB PhD Source Type: blogs
Intranasal administration of a live-attenuated recombinant newcastle disease virus expressing the SARS-CoV-2 Spike protein induces high neutralizing antibody levels and protects from experimental challenge infection in hamsters
Vaccine. 2022 Jul 6:S0264-410X(22)00856-8. doi: 10.1016/j.vaccine.2022.07.005. Online ahead of print.ABSTRACTThe emergence of SARS-CoV-2 in December 2019 resulted in the COVID-19 pandemic. Recurring disease outbreaks repeatedly overloaded the public health sector and severely affected the global economy. We developed a candidate COVID-19 vaccine based on a recombinant Newcastle disease virus (NDV) vaccine vector, encoding a pre-fusion stabilized full-length Spike protein obtained from the original SARS-CoV-2 Wuhan isolate. Vaccination of hamsters by intra-muscular injection or intra-nasal instillation induced high neutrali...
Source: Vaccine - July 12, 2022 Category: Allergy & Immunology Authors: Rik L de Swart Olav S de Leeuw Nadia Oreshkova Nora M Gerhards Irina C Albulescu Sandra Vreman Jos é L Gonzales Riks Maas Frank J M van Kuppeveld Peter Soema Berend-Jan Bosch Ben P H Peeters Source Type: research
JMM Profile: Louping ill virus
J Med Microbiol. 2022 May;71(5). doi: 10.1099/jmm.0.001502.ABSTRACTLouping ill virus (LIV) is a single-stranded, positive-sense RNA virus within the genus Flavivirus that is transmitted to vertebrate hosts by bites from infected ticks, the arthropod vector. The virus affects livestock in upland areas of Great Britain and Ireland, resulting in a febrile illness that can progress to fatal encephalitis. Prevention of the disease is facilitated by combining acaricide treatment, land management and vaccination strategies. However, vaccines have been discontinued in recent years. Although rare, LIV can be transmitted to and caus...
Source: Journal of Medical Microbiology - May 23, 2022 Category: Microbiology Authors: Arran J Folly Lorraine M McElhinney Nicholas Johnson Source Type: research
BCG Vaccination: A potential tool against COVID-19 and COVID-19-like Black Swan incidents
Int Immunopharmacol. 2022 May 17;108:108870. doi: 10.1016/j.intimp.2022.108870. Online ahead of print.ABSTRACTThe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the coronavirus disease 2019 (COVID-19), and its variants have brought unprecedented impacts to the global public health system, politics, economy, and other fields. Although more than ten COVID-19 specific vaccines have been approved for emergency use, COVID-19 prevention and control still face many challenges. Bacille Calmette-Guérin (BCG) is the only authorized vaccine used to fight against tuberculosis (TB), it has been hy...
Source: International Immunopharmacology - May 21, 2022 Category: Allergy & Immunology Authors: Wenping Gong Yingqing Mao Yuexi Li Yong Qi Source Type: research
